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find Author "张亚梅" 2 results
  • Glucometabolic State of Patients with Coronary Artery Disease but without Diagnosed Diabetes

    Objective?To explore the glucometabolic state of angiographically documented inpatients with coronary artery disease (CAD) but without diagnosed diabetes mellitus (DM). Methods?The study recruited 449 patients, who were performed a coronary angiography as well as an oral glucose tolerance test (OGTT) when admitted in the cardiovascular medical ward in our hospital from January 2007 to May 2009. According to the results of coronary angiography, the patients were divided into a coronary artery disease (CAD) group and a non-coronary artery disease (non-CAD) group, and abnormal glucose metabolism (AGM) status was compared between the two groups. Results?The random plasma glucose (RPG) and fasting plasma glucose (FPG) had no significant differences (P values were 0.249 and 0.444, respectively) in the two groups, while the OGTT 2-hour plasma glucose (2hPG) was much higher in the CAD group, with a significant difference (Plt;0.001) compared with the non-CAD group. The CAD group had a prevalence of AGM up to 74.0%, of which 32.1% were newly diagnosed DM patients, and 39.0% were impaired glucose tolerance (IGT) patients, much higher than that in the non-CAD group, respectively, there being a significant difference (P=0.006). Logistic regression analyses revealed that the risk of IGT and newly diagnosed DM was 1.6 times (OR=1.603, 95% CI 1.023 to 2.512, P=0.04) and 2.3 times (OR=2.292, 95% CI 1.391 to 3.777, P=0.001) as much as that in non-CAD patients, respectively; when adjusted for the factors such as hypertension, dyslipidemia, BMI, hs-CRP, and other factors, CAD patients still had a higher risk of newly diagnosed DM (OR=1.852, 95%CI 1.064 to 3.223, P=0.029), compared with the non-CAD patients. Conclusion?AGM is common in the admitted patients with CAD but undiagnosed diabetes, most of whom need an OGTT to be diagnosed timely and accurately. OGTT should be considered to be a routine inspection item to diagnose AGM in the inpatients with CAD; if possible, all hospitalized patients with cardiovascular disease should be performed an OGTT routinely.

    Release date:2016-09-07 11:23 Export PDF Favorites Scan
  • 地震致颅脑伤患者早期血凝机制探讨

    【摘要】 目的 总结地震致颅脑伤患者凝血功能及疾病严重程度判别的临床意义。 方法 2008年5月12-30日,对收治的地震致颅脑伤患者按GCS评分分为Ⅰ、Ⅱ、Ⅲ组,Ⅰ组:13~15分10例;Ⅱ组:9~12分21例;Ⅲ组:3~8分9例;另择单纯软组织挫伤患者9例为对照组,分别检测凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)及血小板的指标。 结果 颅脑伤组PT、APTT、TT、FIB、血小板与对照组比较差异有统计学意义;其凝血功能异常变化与疾病严重程度相关。 结论 检测PT、APTT、TT、FIB及血小板变化可以了解颅脑地震伤者的凝血功能及判断疾病的严重程度,有助于颅脑地震伤患者的诊断和治疗。

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
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