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find Author "张明珠" 4 results
  • RESEARCH PROGRESS OF STEM CELLS TRANSPLANTATION FOR TREATING DIABETIC FOOT

    Objective To introduce the basic research and cl inical appl ication of stem cells transplantation for treating diabetic foot. Methods The recent original articles about the stem cells transplantation for treating diabetic foot were extensively reviewed. Results Transplanted different stem cells in diabetic foot could enhanced ulceration heal ing in certain conditions, increase neovascularization and avoid amputation. Conclusion Stem cells transplantation for treating diabeticfoot may be a future approach.

    Release date:2016-09-01 09:05 Export PDF Favorites Scan
  • SURGICAL REPAIR OF CHRONIC TEARS OF THE SECOND PLANTAR PLATE

    Objective To explore the operative methods and the short-term effectiveness to repair chronic tears of the 2nd plantar plate. Methods Between June 2012 and June 2013, 14 patients with chronic tears of the 2nd plantar plate were treated. There were 4 males and 10 females with an average age of 65.9 years (range, 51-82 years) and with an average disease duration of 6.2 years (range, 5-9 years). The left side was involved in 5 cases and the right side in 9 cases. One patient had simple hammer toe; 2 patients had hallux valgus and claw toe; and 11 patients had hallux valgus and hammer toes. All of them had unstable the 2nd metatarsophalangeal joints. The results of modified Lachman test and drawer test were positive. The surgical treatment included a Weil osteotomy and plantar plate repair operation for rupture via dorsal incision after correcting hallux valgus. Results Primary healing of incision was obtained in all patients. Twelve patients were followed up 6-12 months (mean, 8.2 months). Hallux valgus, claw toe, and hammer toe were all corrected. The results of modified Lachman test and drawer test were negative at 3 months after operation. Mild pain of the 2nd metatarsophalangeal joint occurred, but no stiff was observed in 2 cases at 6 months after operation. The midfoot and forefoot score of American Orthopedic Foot and Ankle Society (AOFAS) was 90.50 ± 3.73 at last follow-up, which was significantly higher (t=21.724, P=0.000) than preoperative score (57.33 ± 4.99). Conclusion The plantar plate is the key to maintain the stability of the metatarsophalangeal joints, and surgical repair can achieve good short-term effectiveness in treating chronic tears of the 2nd plantar plate.

    Release date:2016-08-31 10:53 Export PDF Favorites Scan
  • DOUBLE ARTHRODESIS THROUGH A SINGLE MEDIAL INCISION APPROACH FOR FLATFOOT

    ObjectiveTo investigate the effectiveness of double arthrodesis to correct flatfoot deformity with pes valgus. MethodsBetween May 2009 and May 2012, 12 patients with flatfoot deformity and pes valgus were treated using subtalar and talonavicular joints arthrodesis through a single medial incision approach. There were 5 males and 7 females with an average age of 53.3 years (range, 21-78 years), including 5 left feet and 7 right feet. Of them, 11 cases had posterior tibial tendon dysfunctions; 6 cases were at Johnson-Strom stageⅢ, 5 cases at stageⅡ(c); and 1 case had tarsal coal ition. Preoperative American Orthopaedic Foot and Ankle Society (AOFAS) score and visual analogue scale (VAS) score were 48.75±3.46 and 6.08±1.14, respectively. ResultsThe mean operation time was 85.6 minutes (range, 65-125 minutes). Eleven patients were followed up for 19.4 months on average (range, 13-30 months). All of the cases obtained primary healing of incision, with no complication of infection and nerve or blood vessel injury. X-ray film showed that the mean time of bone union was 9.8 weeks (range, 7-18 weeks); no bone nonunion occurred. No loosening or breakage of internal fixation was observed. Pain occurred at the calcaneal-cuboid joint (1 case) and at fixation site (1 case), and was relieved after symptomatic treatment. The mean AOFAS score and VAS score were significantly increased to 81.36±2.98 and 0.72±0.11 respectively, showing significant differences when compared with preoperative scores (t=19.946, P=0.000; t=16.288, P=0.000). ConclusionSubtalar and talonavicular joints arthrodesis by a single medial incision approach is a useful alternative to tri ple arthrodesis for the correction of flatfoot deformity with pes valgus

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  • KL-6联合肺功能在多发性肌炎/皮肌炎合并间质性肺疾病中的应用价值

    目的 探讨血清KL-6和肺功能检测在多发性肌炎(polymyositis,PM)/皮肌炎(dermatomyositis,DM)合并间质性肺疾病(interstitial lung disease,ILD)中的临床应用价值。方法 采用回顾性分析,纳入初发PM/DM患者(n=64)临床资料,分为间质肺组(n=40)和无间质肺组(n=44),另选健康对照组40例,比较三组患者血清KL-6水平及肺功能在两组的差异并分析其在PM/DM-ILD组中的应用价值。结果 间质肺组患者KL-6水平明显高于无间质肺组(P<0.01);间质肺组患者VC%pred、MVV%pred、FEV1%pred、DLCO%pred、DLCO/VA%pred、TLC%pred均低于无间质肺组(P均<0.05);ROC曲线分析得出PM/DM患者中血清KL-6诊断ILD敏感性为84%,特异性为87.5%,DLCO%pred诊断ILD的敏感性为97.7%,特异性为57.5%,而二者联合检测敏感性为90.5%,特异性为82.5%;间质肺组血清KL-6与VC%pred、MVV%pred、FVC%pred、FEV1%pred、DLCO%pred成反比,与FEV1/FVC%pred成正比(P均<0.05);PM/DM发生ILD的危险因素:AST降低、KL-6升高及DLCO%pred降低。结论 PM/DM患者联合检测血清KL-6和肺弥散功能可提高ILD诊断效能,KL-6和肺功能可能预测ILD的发生及疾病活动度,可指导临床。

    Release date:2024-01-06 03:59 Export PDF Favorites Scan
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