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find Author "张铭连" 10 results
  • 先天性视网膜劈裂并玻璃体积血一例

    Release date:2016-09-02 06:12 Export PDF Favorites Scan
  • 前部缺血性视神经病变的图形视觉诱发电位改变

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • 甲醇中毒性视神经病变的图形诱发电位

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  • 原发性双侧血管闭塞性视神经视网膜病变一例

    Release date:2016-09-02 06:21 Export PDF Favorites Scan
  • 非动脉炎性前部缺血性视神经病变患者血液流变学指标观察

    Release date:2016-09-02 05:25 Export PDF Favorites Scan
  • Leber遗传性视神经病变患者线粒体DNA检测分析

    Release date:2016-09-02 05:51 Export PDF Favorites Scan
  • 慢性甲醇中毒性视神经病变26例临床分析

    目的 探讨慢性甲醇中毒性眼部损害的临床特点。 方法 对26例慢性甲醇中毒患者进行了眼底、视野、眼电生理及眼底荧光血管造影检查,分析其结果。 结果 该组患者视力明显受损,早期眼底视盘色泽正常,晚期表现为视神经萎缩,周边视野先受损害,逐渐向中心侵犯,视诱发电位P100波潜伏期延长,振幅值下降。 结论 甲醇中毒性眼损害主要部位在视神经,预后较差。 (中华眼底病杂志,1998,239-240)

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • Clinical features of patients over 30 years old with Leber hereditary optic neuropathy

    ObjectiveTo observe the clinical features of patients over 30 years old with Leber hereditary optic neuropathy (LHON). MethodsNine male LHON patients (18 eyes) were enrolled in this study. The patients aged from 34 to 56 years old, with an average age of (45.22±6.91) years. The course of the disease ranged from 7 days to 21 months, with a mean course of 5 months. Visual acuity, slit lamp microscope, chromoptometry, direct ophthalmoscope and fundus photography were measured for all patients, visual field examined for 6 patients (11 eyes). Mitochondrial DNA mutation was analyzed. The visual acuity was followed-up for 12 months. ResultsSeven of the 9 patients (77.78%) had family history. Five patients (55.56%) had both eyes involved simultaneously, and 4 patients (44.44%) had the eyes involved at different time. Three patients (33.33%) had sudden visual loss, and 6 patients (66.67%) had gradual visual loss. The visual acuity was light perception in 1 eye (5.55%), finger counting in 3 eyes (16.67%), 0.01-0.1 in 7 eyes (38.89%), 0.12-0.3 in 3 eyes (16.67%), equal or greater than 0.4 in 4 eyes (22.22%). Sixteen eyes (88.88%) had normal light reflex, 1 eye (5.55%) had no light reflex, and 1 eye (5.55%) had relative afferent papillary defect. Eight eyes (44.44%) had normal optic disk, 3 eyes (16.67%) had blurred optic disc border and disc telangiectasia, 7 eyes (38.89%) had pale disc and clear boundary. Among 11 eyes underwent visual field examination, 9 eyes (81.82%) had central or paracentral scotoma and 2 eyes (18.18%) had visual field narrowing. Among 9 patients, there were 7 patients (77.78%) with G11778A mutation, 1 patient (11.11%) with G11696A mutation, and 1 patient (11.11%) with T14484C mutation. In the last follow-up, the visual acuity was light perception in 1 eye (5.55%), finger counting in 4 eyes (22.22%), 0.01-0.1 in 6 eyes (33.33%), 0.12-0.3 in 3 eyes (16.67%), equal or greater than 0.4 in 4 eyes (22.22%).The visual acuity was improved in 9 eyes (50.00%), stable in 7 eyes(38.89%), and decreased in 2 eyes (11.11%). ConclusionLHON patients (older than 30 years) are more common in men, mostly with normal light reflex, central or paracentral scotoma and G11778A mutation.

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  • 自身免疫性视神经炎一例

    Release date:2020-10-19 05:11 Export PDF Favorites Scan
  • 以前段缺血性视神经病变为首发症状的多发性骨髓瘤一例

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