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find Keyword "弥漫性肺泡出血" 2 results
  • Clinical Analysis of 17 Patients with DiffuseAlveolar Hemorrhage

    Objetive To investigate the clinical characteristics, diagnosis, and treatment for diffuse alveolar hemorrhage. Methods The clinical data of 17 patients admitted to respiratory ICU with diffuse alveolar hemorrhage from July 1998 to May 2008 were reviewed. Results In the 17 cases, Wegener granulomatosis accounted for 6 cases, microscopic polyangiitis for 3 cases, systemic lupus erythematosis for 4 cases,mitral stenosis for 2 cases, and idiopathic pulmonary hemosiderosis for 1 cases. Clinical presentations included fever ( 76. 4% ) , hemoptysis( 47% ) , anaemia ( 100% ) , dyspnea ( 100% ) , hypoxaemia ( 100% ) ,and elevated total count of white blood cells ( 76. 4% ) . The titer of antineutrophil cytoplasmic antibody ( c-ANCA, p-ANCA) was 1∶( 46. 0 ±3. 7) , 1 ∶( 108. 0 ±16. 1) , respectively. Hemoglobin was ( 78. 0 ±2. 4) g/L. Bronchoalveolar lavage fluid presented with blood accounted for 35. 3% . Siderophages was found in all cases. Computed tomography showed areas of consolidation interspersed with areas of ground-glass attenuation and reticular interstitial opacities. Mortality was 29. 4% . Conclusions Diffuse alveolar hemorrhage is an acute life-threatening event. The clinical presentations of hemoptysis, dyspnea, and anaemia, and chest imaging studies provide clues to diagnosis of diffuse alveolar hemorrhage. Corticosteroids and immunosuppressive agents have proven effective in diffuse alveolar hemorrhage.

    Release date:2016-08-30 11:54 Export PDF Favorites Scan
  • 支气管扩张合并显微镜下血管炎一例并文献复习

    目的报道一例支气管扩张合并显微镜下血管炎的诊治经过并进行文献复习,提高临床医生对此类疾病的认识及诊治水平。方法报道 1 例支气管扩张合并显微镜下血管炎的病史、临床表现及诊治经过,并复习国内外相关文献报道。结果患者女性,68 岁,因“间断咯血 10 余年,乏力 1 个月,发热 3 d”入院,胸部 CT 示支气管扩张合并感染,ANCA 过筛试验阳性(1∶320),抗髓过氧化物酶抗体阳性(++),肾穿刺病理符合显微镜下血管炎。入院后病情进展,出现严重的弥漫性肺泡出血,经气管插管机械通气、糖皮质激素冲击联合环磷酰胺、血浆置换、丙种球蛋白及抗感染等治疗,病情好转出院,随访 1 年病情稳定。国内外文献显示,支气管扩张是显微镜下血管炎患者肺部累及的常见表现,部分患者在血管炎发病之前存在多年的支气管扩张病史,慢性气道感染可能与血管炎的发病有关,合并支气管扩张的血管炎患者出现弥漫性肺出血风险较高。结论支气管扩张与显微镜下血管炎可能存在一定的内在关系。

    Release date:2021-02-08 08:11 Export PDF Favorites Scan
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