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Research progress of microRNA-215 gene

At present, there are relatively many clinical gene studies. microRNA -215 (miR-215) is a miRNA induced by p53. It exists in animals and humans. miR-215 can exist not only in tumor tissues, but also in blood, urine and feces. miR-215 is abnormally expressed in a variety of tumors and plays a role in promoting and inhibiting cancer. Therefore, miR-215 may provide a new research direction for tumor diagnosis, treatment and prognosis. This paper reviews the expression of miR-215 as a oncogene and tumor suppressor gene in tumors and in non tumors.

Experience of Prevent Parathyroid Damage During Thyroidectomy

目的　探讨甲状腺手术中预防甲状旁腺损伤的方法。方法 回顾性分析我院从2009年1月至2011年5月期间收治的82例甲状腺手术患者的临床资料。结果　82例中行双叶甲状腺全切除术57例，一侧腺叶切除＋对侧腺叶次全切除术25例。术后甲状旁腺损伤的发生率为0.24% （2/82），无永久性甲状旁腺功能低下病例发生。结论 在甲状腺手术中，保留甲状腺下动脉至关重要。保留甲状腺下动脉可保证甲状旁腺的充足血供，可很好的预防甲状旁腺的损伤。

Clinical Research Status of Auxiliary Heterotopic Liver Transplantation

Objective To summarize clinical application status of auxiliary heterotopic liver transplantation. Methods Reviewed relevant literatures and made a summary. Indications, contraindications, surgical treatment, therapeutic efficacy, and existing problems of auxiliary heterotopic liver transplantation were summed up. Results Main indication of auxiliary heterotopic liver transplantation is fulminant liver failure, and with no absolute contraindications. Partial liver transplantation is more popular. The therapeutic efficacy of auxiliary heterotopic liver transplantation is confirmed, but there are still some problems needed to be solved. Conclusion Auxiliary heterotopic liver transplantation is an effective method and replacement therapy for acute and chronic liver failure.

原发性甲状腺淋巴瘤1例报道

腹腔镜下食管裂孔疝修补术的临床疗效分析

目的 回顾性分析腹腔镜下食管裂孔疝修补术的临床手术效果。 方法 回顾 2013 年 1 月—2015 年 12 月收治的 38 例食管裂孔疝患者的临床资料，其中 21 例行腹腔镜手术（腹腔镜组），17 例行开腹手术（开腹手术组），所有患者均采用食管裂孔疝专用补片修补并加固食管裂孔，缝合膈肌脚，术中行胃底折叠术抗反流（Nissen 胃底折叠术）或改良术式。对比分析两组患者情况。 结果 所有患者手术均顺利完成。腹腔镜组手术时间平均（110±5）min，术中出血量平均（70±6）mL，术后住院时间平均（8±2）d；开腹手术组手术时间平均（150±6）min，术中出血量平均（150±10）mL，术后住院时间平均（12±2）d；两组比较差异有统计学意义（P<0.05）。两组患者随访 3～36 个月，平均（20±3）个月，术后主要症状均得到缓解。腹腔镜组术后仍有术前不适症状 2 例，烧心反酸1 例，胸骨后疼痛 1 例。开腹手术组复发 1 例，胸骨后疼痛不适 4 例，反酸 3 例。 结论 腹腔镜下食管裂孔疝修补术相对开腹手术具有手术时间短、术中出血量少及并发症少等优点，值得临床推广应用。