目的 探讨功能性排便障碍人群心理评估中心理和情绪的变化。方法 采用SCL-90、SAS和SDS量表对72例功能性排便障碍患者进行心理评估并分析结果。结果 便秘组SCL-90测试的总分以及躯体化、抑郁、焦虑及精神病性这4项因子的评分结果均高于对照组（P＜0.001），2组其余各因子的评分结果差异没有统计学意义（P＞0.05）。便秘组SAS和SDS测试的评分结果均高于对照组，表明便秘组焦虑和抑郁的评分均较对照组高（P＜0.001）。结论 功能性便秘患者不同程度伴随有情绪和情感的异常，因此对该部分患者进行药物干预的同时给予其心理辅导是非常有必要的。
ObjectiveThrough neuropsychological assessment, explore the factors that may cause cognitive impairment in patients with focal epilepsy.MethodsCollected 53 epilepsy patients in outpatients and inpatients of Tianjin Medical University General Hospital from March 2016 to January 2020, including 25 males and 28 females, with an average age of (23.58±13.24) years old, and the course of disease (6.49±7.39), all met the 2017 ILEA diagnostic criteria for focal epilepsy, and there was no history of progressive brain disease or brain surgery. Carry out relevant cognitive assessments for the enrolled patients, use SPSS statistical software to conduct Spearman correlation analysis on the cognitive functions of the study subjects, and further analyze the related factors of cognition through Logistic regression analysis to clarify the factors related to cognition whether it may be a risk factor for cognitive impairment in patients with focal epilepsy.Results Spearman correlation analysis showed that the FIQ of patients with focal epilepsy was related to education level, age of onset, seizure pattern, total number of seizures, AEDs and EEG interval discharge side (P<0.05). Binary Logistic regression analysis shows that among all cognitive-related factors, only the number of AEDs (P=0.003) and EEG interval discharge (P=0.013) are the risk of cognitive impairment in patients with focal epilepsy factor.ConclusionIn the clinical treatment of epilepsy, seizures should be actively controlled, but the types of drugs should be minimized. When there are more than 3 kinds of drugs, surgical treatment or other non-surgical treatments can be considered. At the same time, the EEG should be reviewed regularly to understand the changes in epileptiform discharges between episodes.