west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "成刚" 6 results
  • Commentary on “Interventions to Improve Outpatient Referrals from Primary Care to Secondary Care”

    Release date:2016-08-25 02:51 Export PDF Favorites Scan
  • Commentary on “Pharmaceutical Policies Effects of Reference Pricing, Other Pricing, and Purchasing Policies”

    Release date:2016-08-25 03:36 Export PDF Favorites Scan
  • Clinical Treatment of Patient with Traumatic Subdural Hygroma

    目的:探讨外伤性硬膜下积液的治疗经验。方法:对 46例外伤性硬膜下积液患者的临床资料进行回顾性分析。结果:非手术治疗20例。手术治疗30例次,其中腰蛛网膜下腔置管持续引流脑脊液5例,钻孔外引流19例,骨窗开颅蛛网膜撕口4例,积液腔腹腔分流2例。结论:对外伤性硬膜下积液患者,应采取个性化的综合治疗方法。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • TRACHEA REPAIR AND RECONSTRUCTION WITH NEW COMPOSITE ARTIFICIAL TRACHEA TRANSPLANTATION

    Objective To construct a new composite artificial trachea and to investigate the feasibility of trachea repair and reconstruction with the new composite artificial trachea transplantation in dogs. Methods The basic skeleton of the new composite artificial trachea was polytetrafluoroethylene vascular prosthesis linked with titanium rings at both ends. Dualmesh was sutured on titanium rings. Sixteen dogs, weighing (14.9 ± 2.0) kg, female or male, were selected. The 5 cm cervical trachea was resected to prepare the cervical trachea defect model. The trachea repair and reconstruction was performed with the new composite artificial trachea. Then fiberoptic bronchoscope examination, CT scan and three-dimensinal reconstruction were conducted at immediate, 1 month, and 6 months after operation. Gross observation and histological examination were conducted at 14 months to evaluate the repair and reconstruction efficacy. Results No dog died during operation of trachea reconstruction. One dog died of dyspnea at 37, 41, 55, 66, 140, and 274 days respectively because of anastomotic dehiscence and artificial trachea displacement; the other 10 dogs survived until 14 months. The fiberoptic bronchoscope examination, CT scan and three-dimensinal reconstruction showed that artificial tracheas were all in good location without twisting at immediate after operation; mild stenosis occurred and anastomoses had slight granulation in 6 dogs at 1 month; severe stenosis developed and anastomosis had more granulation in 1 dog and the other dogs were well alive without anastomotic stenosis at 6 months. At 14 months, gross observation revealed that outer surface of the artificial trachea were encapsulated by fibrous connective tissue in all of 10 dogs. Histological examination showed inflammatory infiltration and hyperplasia of fibrous tissue and no epithelium growth on the inner wall of the artificial trachea. Conclusion The new composite artificial trachea can be used to repair and reconstruct defect of the trachea for a short-term. Anastomotic infection and dehiscence are major complications and problems affecting long survival.

    Release date:2016-08-31 04:07 Export PDF Favorites Scan
  • Experimental Study on Novel Hybrid Artificial Trachea Transplantation

    We developed and designed a new type of artificial trachea. The basic structure of the artificial trachea was polytetrafluoroethylene vascular prosthesis linked with titanium rings on both sides. Dualmesh was sutured on titanium rings. This experimentation follows the replacement of trachea in dogs with a combined artificial trachea to investigate the feasibility of this type of prosthesis. Sixteen dogs were implanted with the combined artificial trachea after resection of 5 cm of cervical trachea. The 5 cm-long trachea of dogs on the necks were resected and the reconstruction of the defect of the trachea was performed with trachea prosthesis. According to the method of trachea reconstruction, the models were divided into 2 groups, artificial trachea implantation group (the control group, n=8) and group of artificial trachea implantation with growth factor (the experimental group, n=8). Then computer tomography scan (CT), bronchoscope and pathologic examination were conducted periodically to observe the healing state of the hybrid artificial trachea. None of the dogs died during operation of cervical segmental trachea construction. But four dogs in the control group died of apnea in succession because artificial trachea was displaced and the lumen was obstructed, while 2 dogs died in the experimental group. In the first month there was granulation around anastomosis with slight stenosis. The rest of dogs were well alive until they were sacrificed 14 months later. The mean survival time of the experimental group was longer than that of the control group. The rate of infection, anastomotic dehiscence, severe stenosis and accidental death in the experimental group were lower than the control group (P<0.05).Artificial trachea was encapsulated by fibrous tissue and no mucous membrane was seen in the lumen of the artificial trachea. The artificial trachea can be used to reconstruction of the defect of the trachea with long-term survival of the animals. The unique design of artificial trachea reduces stenosis around anastomosis effectively but infections and split or displacement of the artificial trachea are still major problems affecting long-term survival of the animals. Application of growth factors to a certain extent promotes tissue healing by changing the local environment.

    Release date: Export PDF Favorites Scan
  • 地震致颅脑伤患者早期血凝机制探讨

    【摘要】 目的 总结地震致颅脑伤患者凝血功能及疾病严重程度判别的临床意义。 方法 2008年5月12-30日,对收治的地震致颅脑伤患者按GCS评分分为Ⅰ、Ⅱ、Ⅲ组,Ⅰ组:13~15分10例;Ⅱ组:9~12分21例;Ⅲ组:3~8分9例;另择单纯软组织挫伤患者9例为对照组,分别检测凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)及血小板的指标。 结果 颅脑伤组PT、APTT、TT、FIB、血小板与对照组比较差异有统计学意义;其凝血功能异常变化与疾病严重程度相关。 结论 检测PT、APTT、TT、FIB及血小板变化可以了解颅脑地震伤者的凝血功能及判断疾病的严重程度,有助于颅脑地震伤患者的诊断和治疗。

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content