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find Keyword "抗血管生成" 4 results
  • 抗血管生成与肿瘤微环境关系的研究进展

    血管生成是肿瘤发展、转移的重要条件。以往曾认为抗血管生成可抑制肿瘤生长并减少远处转移。最近的研究表明,抗血管生成治疗不仅可产生耐药,短期应用反而会增加肿瘤转移复发的风险,这与肿瘤微环境的反应性变化密不可分。现就抗血管生成治疗后肿瘤微环境反应性改变的研究进展作一阐述,以期对抗血管生成治疗产生耐药及增加肿瘤转移和复发风险的机制进行更深入的探讨与研究,寻找抗肿瘤治疗的新靶点,从而改善抗肿瘤血管生成治疗的效果。

    Release date:2016-09-07 02:38 Export PDF Favorites Scan
  • Advances of Study on Angiogenesis and Antiangiogenic Therapy in Hepatocellular Carcinoma

    Objective To introduce the possible effects and significances of angiogenesis and antiangiogenic in the development and treatment of hepatocellular carcinoma (HCC). Methods Recently relevant literatures were reviewed. Results Angiogenesis played a significant role in the development and therapy of HCC, and the development and metastasis of HCC could be effectively suppressed by antiangiogenic therapy. This might provide a new approach for the treatment of HCC. Conclusion Comprehending the molecular mechanism of angiogenesis and applying antiangiogenic therapy will contribute a lot for the prevention and treatment of HCC.

    Release date:2016-09-08 10:56 Export PDF Favorites Scan
  • 三阴乳腺癌抗血管生成治疗进展及影像学评价

    三阴乳腺癌(TNBC)是乳腺癌中一个特殊的类型,具有特殊的分子表达类型和生物学特性,内分泌治疗和曲妥珠单抗靶向治疗无效且无明确治疗靶点,复发早、进展快、生存期短、早期易发生远处转移等特点。此类型乳腺癌对常规放射、化学治疗不敏感,导致其预后较其他类型乳腺癌差。对TNBC靶向治疗的深入研究,有助于人们采取更有效的治疗手段来提高疗效。在实体瘤的恶性生长及转移中,肿瘤的新生血管生成起着至关重要的作用,针对新生血管生成靶向治疗的研究成为热点。MRI技术是诊断乳腺癌的最准确的影像学方法,有助于肿瘤诊断、治疗方案制定、治疗反应及预后评估,并能加深对其生物学行为的理解。现对TNBC抗血管生成靶向治疗进展及MRI影像学疗效评价进行综述。

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  • Progress in medical treatment of ovarian cancer

    The mortality rate of ovarian cancer is the highest among female reproductive tract malignancies. Although most patients have undergone recurrent treatments such as surgery, chemotherapy, and targeted therapy, the recurrence rate is still high. The exploration of scholars in this field has never stopped. In recent years, remarkable achievements have been made in the medical treatment of ovarian cancer. The research of poly adenosinediphosphate-ribose polymerase, immunotherapy (immunocheckpoint inhibitor monotherapy, immune checkpoint inhibitor combined with other drugs) and anti-angiogenic drugs have provided new methods for the treatment of this disease, and throughout the whole process of ovarian cancer treatment. This paper summarizes this, and aims to provide a reference for the clinical treatment of ovarian cancer.

    Release date:2021-04-15 05:32 Export PDF Favorites Scan
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