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find Keyword "支架" 478 results
  • The progress of research on three-dimensional printed jaw scaffolds

    Large defects of jaw caused by tumor, trauma and so on in oral and maxillofacial region lead to facial deformity, language and chewing dysfunction, which severely damage the patient’s life quality. Three-dimensional printing (3DP) is also named additive manufacturing (AM), which can print materials layer by layer to create three-dimensional objects. The complex shape of jaw defects can be accurately reconstructed using 3DP scaffold combined with image data, computer-aided-design and manufacture. It has specific advantages compared with traditional way of jaw reconstruction and has attracted much attention in the field of jaw tissue engineering recently. This article presented the progress of 3DP scaffold and its application in jaw reconstruction, providing a new idea for jaw reconstruction.

    Release date:2017-12-21 05:21 Export PDF Favorites Scan
  • CLINICAL APPLICATION OF BIO-DERIVED BONE TRANSPLANTATION WITH TISSUE ENGINEERINGTECHNIQUE:YEAR FOLLOW-UP

    To summarize the medium-term cl inical result of bio-derived bone transplantation in orthopedics with tissue engineering technique. Methods From December 2000 to June 2001, 10 cases of various types of bone defect were treated with tissue engineered bone, which was constructed in vitro by allogenous osteoblasts from periosteum (1 × 106/ mL) with bio-derived bone scaffold following 3 to 7 days co-culture. Six men and 4 women were involved in this study, aged from 14 to 70 years with a median of 42 years. Among them, there were 2 cases of bone cyst, 1 case of non-union of old fracture, 6 cases of fresh comminuted fracture with bone defect, and 1 case of chronic suppurative ostemyel itis. The total weight of tissue engineered bone was 3-15 g in all the cases, averaged 7.3 g in each case. Results The wound in all the case healed by first intention. For 7 year follow up, bone union was completed within 3.0 to 4.5 months in 9 cases, but loosening occurred and the graft was taken out 1 year after operation in 1 case. The X-ray films showed that 9 cases achieved union except one who received resection of the head of humerus. No obvious abnormities were observed, and the function of affected l imbs met daily l ife and work. Conclusion Bio-derived tissue engineered bone has good osteogenesis. No obvious rejection and other compl ications are observed in the cl inical appl ication.

    Release date:2016-09-01 09:12 Export PDF Favorites Scan
  • PREPARING TRESTLE OF TISSUE ENGINEERING FOR SKIN WITH COLLAGEN

    OBJECTIVE: To build the trestle of tissue engineering for skin with the collagen. METHODS: The collagen was obtained from the baby cattle hide pretreated by Na2S and elastinase and Protease M, then the collagen was dissolved in 0.5 mol/L acetic acid solution. The collagen was treated with Protease N to minimize its immunogenicity. The resulting collagen could be used to build the trestle of tissue engineering for skin because of good biocompatibility. The collagen molecular weight and structure were analyzed by SDS-PAGE. The bioactivity of trestle was tested in the experiment of the mice wound healing and the cell implantation. RESULTS: The SDS-PAGE result of the collagen treated by Protease M showed the typical spectrum of type I collagen. The built trestle was a collagen sponge matrix in which micropore size was 50-200 microns. It could accelerate wound healing and the implanted fibroblasts could proliferate well. CONCLUSION: The collagen treated by Protease N can get good biocompatibilily and is suitable for building the trestles of tissue engineering for skin with good bioactivity.

    Release date:2016-09-01 09:35 Export PDF Favorites Scan
  • CONSTRUCTION OF THE SCAFFOLD MODEL FROM HETEROGENEOUS SMALL BLOOD VESSELS

    Objective To establish a scaffold model from heterogeneoussmall blood vessels. Methods Caudal arteries from 34 Wistar rats( average length 12.08±1.69 cm) were made into acellular blood vessel scaffolds. Some scaffoldswere observed by electron microscope, and others were transplanted to the cut ends of ear central arteries of male Japanese big ear white rabbits. Results Average external diameter was 0.74±0.08 mm in proximal, and 0.55±0.08 mm in distal end of rat caudal arteries. The small blood vessel scaffolds had shin wall whichwas white and soft, composed of fibrous tissues without cells. On the intima surface the fibrous tissues were arrayed densely in a grid-like pattern. After transplantation, the blood flow was reserved, and kept flowing freely in 24 hours. The pulsation of the transplanted artery was accessible and no blood leakage wasfound.Conclusion The natural scaffolds are composed of fibrous tissues, and can sustain the artery pulse pressure for 24 hours. It is better to suture the blood vessels by sleeve anastomosis. 

    Release date:2016-09-01 09:29 Export PDF Favorites Scan
  • Treating Distal Radius Fracture Using External Fixator

    目的:评价外固定支架治疗桡骨远端骨折的疗效。方法:2004年3月至2008年8月以外固定支架或辅以克氏针、可吸收螺钉内固定治疗桡骨远端骨折37例。结果:31例获得4~28 个月(平均14 个月)的随访,所有骨折均临床愈合,平均愈合时间8周。腕关节功能按Sarmiento标准进行评定,优17例,良9例,可4例,差1例,优良率839%。结论:外固定支架治疗桡骨远端骨折疗效可靠,值得推广。

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
  • PRODUCTION AND APPLICATION OF BIO-DERIVED SCAFFOLD IN PERIPHERAL NERVE

    Objective To comment on the recent advances of production and application of the bio-derived scaffold in the tissue engineered peripheral nerve. Methods The recent articles were systematically analyzed, and then the production methods of the bio-derived scaffold and its application to the tissue engineered peripheral nerve were evaluated and prospected. Results B iological tissues were processed by some methods to produce the bio-derived materials. These mat erials could maintain the structure and components of the tissues. Moreover, the immunogenicity of these materials was reduced. Conclusion Application of the bio-derived materials is a trend in the fabricating scaffold of the tissue en gineered peripheral nerve.

    Release date:2016-09-01 09:25 Export PDF Favorites Scan
  • 胸主动脉瘤及主动脉夹层外科治疗进展

    胸主动脉瘤及主动脉夹层病情凶险,死亡率和病残率均很高.近几年在保留和不保留主动脉瓣的主动脉根重建术治疗升主动脉瘤,弓部主动脉瘤切除与脑保护,胸主动脉瘤或胸腹主动脉瘤切除与脊髓保护,以及主动脉腔内支架移植术等方面取得了较大的进展.手术死亡率已从31.4%下降至3.3%~4.8%.胸主动脉瘤,特别是主动脉夹层系一全身性主动脉病变,近年来手术疗效有所改善,但远期复发率和再手术率仍较高.主动脉内支架移植与外科手术结合应用,对复杂的伴有降主动脉病变的A型主动脉夹层治疗,可能是一种安全而有效的方法.

    Release date:2016-08-30 06:30 Export PDF Favorites Scan
  • RECENT PROGRESS OF RESEARCHES IN CARTILAGE TISSUE ENGINEERING

    Objective To review the recent progress of the researches in the field of cartilage tissue engineering, and to discuss the challenges in construction of tissue engineered cartilage. Methods Literature related with cartilage tissue engineering was reviewed and analyzed. Results Some techniques have been appl ied in cl inical. As far as the seeding cells, induced pluripotent stem cells have attracted much more attention. Current strategies of scaffold designing are trying to imitate both component and structure of natural extracellular matrix. Cartilage regeneration through the autologous cell homing technique el iminate the transplantation of exotic cells and has become the hot topic. Conclusion Successful treatment of the damaged cartilage using tissue engineering method will depend on the advances of stem cell technology development, biomimetic scaffolds fabrication and proper appl ication of growth factors.

    Release date:2016-08-31 05:42 Export PDF Favorites Scan
  • UNILATERAL EXTERNAL FIXATOR IN THE TREATMENT OF INTERTROCHANTERIC FRACTURES OF FEMUR

    Forty cases of intertrochanteric fractures of femur were treated with percutaneous nonmetallic external fixator. The patients were followed up for 6 months to 3 years, and the fractures were all united without coxa vara or shirtening deformities. There was no mortality in this series. This method had the advantages ofbeing simple, save time and effort, less traumatic and early ambulation. The design of the apparatus tallied with the biomechanics of the neck and shaft of the femur.

    Release date:2016-09-01 11:12 Export PDF Favorites Scan
  • Treatment of the SubAcute and Old Scaphoid Fracture by Internal Fixation with Herbert Screws and Orthopedic External Fixation Support

    【摘要】 目的 评价切开复位Herbert螺钉内固定加外支架治疗对亚急性和陈旧性舟状骨骨折的治疗效果。方法 2008年2月—2009年5月,对15例受伤后4周以上(平均7.6周)入院诊断为亚急性和陈旧性舟状骨骨折的患者均采用Herbert螺钉内固定加外支架治疗,术后随访5~16个月,平均12.5个月,按Gartland amp; Werley和改良Green amp; O’Brein评分系统进行评价治疗效果。结果 15例患者均进行有效随访,末次随访Gartland amp; Werley评分优8例,良5例,中2例,优良率为86.7%,改良Green amp; O’Brein评分优7例,良5例,中3例,优良率为80%。结论 此方法是治疗亚急性和陈旧性舟状骨骨折的有效措施,值得推广。

    Release date:2016-09-08 09:37 Export PDF Favorites Scan
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