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find Author "景玉婷" 2 results
  • CD90与肿瘤关系的研究进展

    恶性肿瘤作为21世纪威胁人类生存和健康的最主要因素,其发病机制尚不清楚,目前仍缺乏特异的诊断方式及有效的治疗手段。“肿瘤干细胞理论”的提出为人们的研究提供了新思路,而CD90作为“肿瘤干细胞”分选的表面标志物已在肝癌、肺癌、神经母细胞瘤等恶性肿瘤中进行了研究,结果表明其可能参与了细胞坏死、凋亡、转移、黏附等多种与肿瘤进展密切相关的过程。同时,CD90作为一种细胞表面的糖蛋白分子,在成纤维细胞、造血干细胞、神经细胞等许多类型的细胞中均有表达,并对细胞与细胞间,细胞与间质间的反应起着调节作用。然而,CD90在肿瘤中的具体作用及相关机制,目前尚存在着争议。现就CD90在肿瘤中的作用及其机制作一综述。

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  • Clinical and Pathological Characteristics of Lung Carcinoma in Young Adults

    ObjectiveTo explore the clinical and pathological characteristics of lung carcinoma in young adults, and improve the early diagnosis and treatment. MethodsWe retrospectively analyzed 129 patients with lung carcinoma aged from 18 to 35 years old who came to West China Hospital of Siduan University from January 1st 2008 to December 31st 2014.Also we collected 32 young adults with lung benign mass to make the comparison of the clinical and pathological characteristics with the patients. ResultsIn the 129 patients with lung carcinoma, there were 72 females and 57 males.Adenocarcinoma (88/129) was the most common type of pathology, while others included small cell carcinoma (18/129), squamous cell carcinoma (13/129), and other types of carcinoma (10/129).Among patients with lung carcinoma, 41(31.8%) complained of refractory dry cough and another 40(31.0%) presented coughing and expectoration.Twenty-nine patients (22.5%) were misdiagnosed in their first visits.In young adults with lung carcinoma, 55.8% were at the Ⅳ stage with metastasis at the first-time diagnosis.Comparing with patients with benign lung mass, patients with lung carcinoma presented significantly more dry cough (P=0.011), chest distress (P=0.007) and weight loss (P=0.007);while fever was found more patients with lung benign mass (P=0.040).The differences in cough, expectoration, and emptysis between the two groups were not significant (P > 0.05). ConclusionsLung carcinoma in young adults often has atypical clinical presentations.Therefore, it is more commonly misdiagnosed.

    Release date:2016-12-27 11:09 Export PDF Favorites Scan
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