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find Author "曾莉钧" 2 results
  • 心肌致密化不全研究进展

    心肌致密化不全是由胚胎期心肌正常致密化过程失败导致的心肌病,形态学特征为心室腔内突出的肌小梁和与左室腔交通且深陷的小梁间隙,多以心功能不全、体循环栓塞、心律失常为临床表现。诊断主要依靠影像学检查,常用的有超声心动图和核磁共振成像。近年的研究发现心肌致密化不全与左室发育相关的基因突变密切相关。通过简述心肌致密化不全目前的研究进展,为临床诊断及治疗提供依据。

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  • Radiofrequency Catheter Ablation for Atrial Tachycardia in Patients after Radiofrequency Ablation of Atrial Fibrillation during Mitral Valve Replacement

    ObjectiveTo investigate heart rhythm outcomes of radiofrequency ablation (RFA)of atrial fibrillation (AF)during mitral valve replacement (MVR)for patients with rheumatic heart disease (RHD), and explore clinical results of radiofrequency catheter ablation (RFCA)for postoperative atrial tachycardia (AT). MethodsEleven RHD patients who developed AT after RFA of AF during MVR were enrolled in this study. There were 4 males and 7 females with their age of 49±8 years. Electroanatomic mapping of the left or right atrium was conducted with three-dimensional electroana-tomic mapping system during continuous AT. RFCA was performed at the key areas of AT. ResultsFor MVR, operation time was 149±18 minutes, postoperative hospital stay was 9.5±2.9 days, and length of ICU stay was 1.8±0.4 days. During electroanatomic mapping, 17 ATs were recorded in 11 patients. Six ATs (35%)of 5 patients originated from the right atrium and 11 ATs (65%)of 6 patients originated from the left atrium (LA). Among them, AT of 2 patients was related to the mitral valve ring. Immediate success of RFCA was obtained in 91% (10/11). After a mean follow-up of 17±4 months, 2 patients whose AT originated from LA had AT recurrence. ConclusionsMajority of postoperative ATs originate from LA, and majority of ATs are not mitral-dependent. RFCA is an effective and safe procedure for AT in patients after RFA of AF during MVR.

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