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find Keyword "朗格汉斯组织细胞增生症" 3 results
  • 成人单纯颈椎朗格汉斯组织细胞增生症的临床诊疗

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  • Preliminary study on surgical treatment of Erdheim-Chester disease

    Objective To summarize the preliminary effectiveness of surgical treatment of Erdheim-Chester disease (ECD), so as to improve the understanding of the disease by orthopedic surgeons. Methods The clinical data of 9 patients with ECD between December 2012 and October 2017 were retrospectively analysed. There were 6 males and 3 females with an median age of 42 years (range, 8-61 years). The disease duration was 4-59 months (mean, 39 months). There were 2 cases of multiple lesions, including 1 case involving soft tissue of the buttocks and bilateral tibia, 1 case involving the sinus, skull base, and proximal right tibia; 7 cases with single lesion, including 3 cases of right femoral neck, 1 case of proximal right tibia, 1 case of right humerus, and 2 cases of ribs. Nine patients were diagnosed according to clinical manifestations, imaging examination, and pathological diagnosis. Four patients underwent needle biopsy before operation and 5 patients were diagnosed by postoperative pathology examination. Five cases underwent lesional scraping and internal fixation, 1 case underwent bone scraping and bone grafting, and 3 cases underwent lesion resection. One of the multiple lesions was treated with interferon and hormone. Results Nine patients underwent the surgery safely. There was no fever, wound exudation, infection, etc., and the incisions healed by first intention. All the patients were followed up 4-59 months with an average of 31.4 months. One patient with bilateral tibia and hip soft tissue involvement continued to receive medical treatment, and the tumor was controlled without significant increasing. The remaining 8 patients were examined for X-ray films at 3, 6, and 12 months after surgery, the bone has been fused and the steel plate and intramedullary nail were firmly fixed, and no tumor recurrence was observed. At 1 year after surgery, the pain symptoms of the patients improved and returned to normal life; 3 of them who involving the right femoral neck walked freely, and the quality of life improved significantly. Conclusion ECD patients can achieve the purpose of eliminating lesions and relieving pain after surgical treatment, and the surgical treatment has the advantages of quick relief of pain, improved quality of life, small side effects, and low economic cost when compared with medical treatment.

    Release date:2018-07-30 05:33 Export PDF Favorites Scan
  • 吸烟相关间质性肺疾病的对比分析

    目的提高对不同类型的吸烟相关间质性肺疾病的临床、影像及病理学特点的认识。方法对诊断为呼吸性细支气管炎伴间质性肺疾病(RB-ILD)、脱屑性间质性肺炎(DIP)、肺朗格汉斯组织细胞增生症(PLCH)患者的临床表现、影像学和组织病理学特点进行分析比较。结果3 例患者,男 2 例,女 1 例,年龄 21~71 岁,吸烟史为 4~50 年,均为慢性起病,主要临床表现为咳嗽、咳痰、活动后气促。胸部高分辨 CT 的主要表现为小叶中央型微结节影、网格影、囊状影。病理学表现:RB-ILD 呼吸性细支气管周围少许炎症渗出、管腔中有少许巨噬细胞;DIP 肺泡腔内巨噬细胞聚集;PLCH 以朗格汉斯细胞组成为主的星状结节,朗格汉斯组织细胞表达 CD1α。结论吸烟相关的间质性肺疾病临床及影像表现各异,增强对这类疾病的认识,结合组织病理学检查有利于及早诊断这类疾病。

    Release date:2020-11-24 05:41 Export PDF Favorites Scan
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