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find Author "朱洪玉" 14 results
  • 右腋下直切口手术治疗先天性心脏病

    目的 通过右腋下直切口治疗先天性心脏病可以达到创伤小、疼痛轻、美观的目的.方法 本组40例患者中,进行单纯型继发孔房间隔缺损修复18例,房间隔缺损并二尖瓣关闭不全修复3例,室间隔缺损修复15例,法洛四联症心内根治术2例,心内型完全性肺静脉异位引流和部分房室管畸形修复各1例.结果 全组无手术死亡.体外循环时间18~66分30秒,主动脉阻断时间为3~52分;术后6~12天出院.结论 微创伤切口先天性心脏病手术能达到完全修复的效果.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • Surgical Technique and Outcomes for Supracardiac Total Anomalous Pulmonary Venous Connection

    Objective To summarize the surgical experience of supracardiac total anomalous pulmonary venous connection(S-TAPVC) and study the surgical technique and outcomes for S -TAPVC. Methods Eightysix patients with S-TAPVC underwent the surgical repair from May 1985 to December 2007. There were 49 males and 37 females. The patients aged from 7 months to 35 years (mean 9.6 years) and weighed from 4.9 kg to 68.0 kg (mean 23.8 kg). The patients were divided into three groups by the approach for the anastomosis. There were 20 patients in groupⅠthrough the right atrium incision, 49 patients in group Ⅱ through the right and left atrium incisions and 17 patients in group Ⅲ through the top of the left atrium incision. The interrupt continuous anastomosis between the common pulmonary venous and the left atrium was used in all patients. The enlarged atrial septal defect(ASD) was repaired with autopericardium. The vertical vein was ligated if the postoperative left atrial pressure was less than 15 mm Hg. But the vertical vein was opened or just partialy ligated if the postoperative left atrial pressure was more than 15 mm Hg. Results There was no early operative death. The postoperative left atrial pressure in three groups were 9.3±3.2 mm Hg, 9.9±2.9 mm Hg and 11.6±3.8 mm Hg, respectively. The cases with open or just partly ligated vertical vein in three groups were 0 case (0%), 7 cases (14.3%) and 2 cases (11.8%), respectively. The cases of arrhythmia in three groups were 5 cases (25.0%), 15 cases (30.6%)and 1 case (5.9%). The severely low cardiac output syndrome occurred in 2 patients and reoperation for bleeding in 2 patients. The morbidity of arrhythmia in group Ⅲ was less than in group Ⅱ(P=0.042). Conclusion The outcome of surgical repair for S -TAPVC is satisfactory. The anastomosis through the top of the left atrium incision has low occurrence of arrhythmia. The anastomosis through the right and left atrium incision is easy to expose and to perform surgery, especial for old children and adult patients.

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • 慢性缩窄性心包炎的外科治疗

    目的 总结慢性缩窄性心包炎的外科治疗经验。方法 78例患者术前均被明确诊断为慢性缩窄性心包炎,均在全身麻醉下经胸部正中切口行心包剥脱术。结果 术后中心静脉压6.5~14.0mmHg(1kPa=7.5mmHg),平均8mmHg。死亡1例,再次开胸止血2例,发生低心排血量综合征3例。术后病理检查:心包纤维结缔组织增生、玻璃样变性60例,呈于酪样结核病变18例(伴结核肉芽肿形成7例)。随访65例,随访时间3个月~10年,心功能(NYHA)均为I级,无心包缩窄复发和死亡。结论 手术是治疗慢性缩窄性心包炎惟一有效的方法,胸部正中切口是较佳的手术径路,心包切除范围应根据具体病情而定,力争将心包彻底松解切除。

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • 主动脉窦瘤破裂的外科治疗

    摘要 目的 总结1973~1999年85例主动脉窦瘤破裂的外科治疗经验。 方法 主动脉窦瘤破裂85例,合并室间隔缺损40例(47.1%),主动脉瓣关闭不全15例(17.6%),均以补片行主动脉窦瘤修补,其中40例以同一补片修补主动脉窦瘤和室间隔缺损,5例同期行主动脉瓣置换术,3例行主动脉瓣成形术。 结果 全组死亡3例,死亡率3.5%,无残余分流等并发症,71例随访2个月~24年,心功能恢复良好。 结论 主动脉窦瘤破裂一经确诊,应尽早手术,采用补片修补主动脉窦瘤及用同一乒乓球拍形补片修补窦瘤和室间隔缺损,效果较好。对于严重的主动脉瓣关闭不全,应同期行主动脉瓣置换术,而轻度主动脉瓣关闭不全可不用特殊处理。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • Surgical correction of complete atrioventricular septal defect associated with tetralogy of Fallot

    Objective To summarize the experience of surgical correction of complete atrioventricular septal defect associated with tetralogy of Fallot(CAVSD-TOF). Methods Twelve patients aged 6-16(11.1±2.8) years underwent correction of CAVSD-TOF. The atrioventricular septal defect was closed through a right atriotomy and longitudinal right ventriculotomy in each case. The three-patch technique was used for the first 7 cases and two-patch technique for the later 5 cases. The commissure between the superior and inferior bridging leaflets of the left portion of the common atrioventricular valve was closed in each patient. Right ventricular outflow tract obstruction was relieved by a transannular patch. Results There were 4 deaths in the early postoperative period, 3 deaths in the first 7 cases compared to 1 death in the later 5 cases. The causes of death included severe low cardiac output syndrome(3 cases) and perfusion pulmonary edema(1 case). Six survivors were followed up from 3 months to 13.5 years. Heart function (NYHA) was class I or Ⅱ in all cases. Conclusion CAVSD-TOF can be corrected by using the two-patch technique and closure of atrioventricular septal defect through a combined approach through right atriotomy and right ventriculotomy. Routine closure of the commissure of the left portion of the atrioventricular valve achieves a low incidence of regurgitation.

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • Outcome of Short and Middle Term of Right Ventricular Outlet Tract Reconstruction with Gore-Tex Monocusp Valve

    Abstract: Objective To evaluate the outcome of reconstruction of right ventricular outlet tract (RVOT) with 0.1 mm Gore-Tex monocusp valve for short and middle term. Methods Between June 2002 to July 2006, 48 patients underwent reconstruction of RVOT with Gore-Tex monocusp valve to correct cardiac anomalies, including 33 patients with tetralogy of Fallot (TOF) and pulmonary stenosis, 8 patients with TOF and pulmonary atresia, 3 patients with TOF and absent pulmonary valve, 2 patients with double outlet of right ventricle and pulmonary stenosis, 1 patient with truncus arterious and 1 patient with complete transposition of great artery, ventricular septal defect and pulmonary stenosis. Results There was no operative death. The postoperative blood oxygen saturation was up to 1.00. The ratioes of right ventricular systolic pressure and left ventricular systolic pressure were between 0.22 to 0.65.The gradient between right ventricle and left or right pulmonary artery was less than 10 mmHg. All patients were followed up including echocardiography ranged from 3 to 48 months. There were no late death and complication. Trivial and mild pulmonary insufficiency was detected in 18 patients and valvular motion remained competent in 40 patients. Conclusion The results suggest that the reconstruction of RVOT with Gore-Tex monocusp valve can achieve excellent outcome for short and middle term.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • The Long Effect of Nonpulsatile Flow on Changes of Structure and Function in Pulmonary Microcirculation

    Objective To investigate the long effect of nonpulsatile flow on changes of structure and function in pulmonary microcirculation and to identify the pulmonary reconstruction under this blood perfusion. Methods Canine models with nonpulsatile flow in the right lung was established, and sacrificed 6 months later. Compare endothelial nitric oxide synthase (eNOS) in vascular endothelium, apoptosis in smooth muscle cell with immunohistochemistry by streptavidinbioepidermmultienzyme complex methodes, and observe structural changes in pulmonary arterioles with optical microscope. Results The expression of eNOS in the right nonpulsatile flow perfusing lung was weaker as compared to the left lung (10 846.7±177.8 vs. 13 136.1±189.6;t=2.240, P=0.040), the fas was ber as compared to the left lung(14 254.1±217.1 vs. 11 976.7±195.7; t=2.160, P=0.040). The ratio of wall thichness/vessel diameter in the right lung(13.64%±12.80% vs. 14.96%±13.10%) and wall area/vessel area(46.40%±11.70% vs. 47.80%±12.20%) was lower as compared to the left lung(Plt;0.05). Conclusion Longterm nonpulsatile flow can decrease the expression of eNOS, contract the muscles in capillary net, and increase pulmonary vascular resistance. Moreover it canincrease the arteriole apoptosis, leading to vascular structure remodeling.

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • The Effect of Ischemic Preconditioning on Myocardial Ischemic Reperfusion of Elderly Rats

    Objective To investigate the effect of ischemic preconditioning(IPC) on myocardial ischemic reperfusion injury(I/R) of elderly rats. Methods Fiftysix Wistar rats, of which there were 28 aged from 21-23months(elderly rat) and 28 aged from 4-5months(young rat), were used to build isolated heart perfusion Langendorff model. The rats were divided into 7 groups with random number table(8 in each group): adult control group, adult I/R group, adult IPC group, elderly control group, elderly I/R group, elderly IPC group and elderly enhanced IPC group. The control group underwent a 90-min perfusion without any intervention; the I/R group underwent a 30-min equilibration period, then a 30-min ischemia and a 30-min reperfusion; the IPC group underwent a 10-min equilibration period, then a 5-min ischemia for twice and a 5-min reperfusion, after that a 30-min ischemia and [CM(158-3mm]a 30-min reperfusion; the enhanced IPC group underwent a 10-min equilibration period, then a 5-min ischemia for 4-times and a 5-min reperfusion, after that a 30-min ischemia and a 30-min reperfusion. The recovery rates of cardiac output(CO), left ventricular developed pressure (LVDP), the maximum rising and descending rate of left ventricular pressure (±dp/dtmax) after a 30-min reperfusion were compared among groups. The activity of creatine kinase (CK) in coronary outflow, the level of malonyldialdehyde (MDA) and superoxide dismutase (SOD) before ischemia and after a 30min reperfusion were detected. The myocardial infarction areas were compared among groups. Results After a 30min reperfusion, compared with adult I/R group, in adult IPC group CK reduced significantly(89.48±18.72 U/L vs. 115.76±16.72 U/L,q=6.061,Plt;0.01),the level of MDA decreased significantly(9.53±3.44 nmol/ml vs. 16.84±2.29 nmol/ml,q=7.732,Plt;0.01),the level of SOD increased significantly(584.7±122.62 U/ml vs. 429.46±85.24 U/ml,q=4.754,Plt;0.01),the recovery rates of CO,LVDP,+dp/dtmax and -dp/dtmax increased ignificantly(78.69%±9.68% vs. 65.10%±8.63%,83.61%±8.46% vs. 67.23±8.68%,81.68±8.68% vs. 67.89%±6.89%,89.79%±7.78% vs. 66.79%±8.46%,Plt;0.01), the myocardial infarction areas reduced significantly (5.25%±4.33% vs. 14.75%±8.02%,q=7.458,Plt;0.01)。There was no statistical significance between elderly IPC group and elderly I/R group in the above indexes(Pgt;0.05).However, There was statistical significances between elderly enhanced IPC group and I/R group. CK reduced significantly (88.60±28.32 U/L vs. 105.76±9.64 U/L,q=5.620,Plt;0.01),the level of MDA decreased significantly(8.38±3.36 nmol/ml vs. 16.80±3.06 nmol/ml,q=7.500,Plt;0.01),the level of SOD increased significantly(558.87±78.66 U/ml vs. 433.75±86.65 U/ml,q=7.335,Plt;0.01),the recovery rates of CO,LVDP,+dp/dtmax and -dp/dtmax increased significantly (77.99%±10.02% vs. 66.26%±9.78%,85.59%±6.67% vs. 73.90%±6.66%,83.87%±9.98% vs. 68.90%±8.68%,86.01%±766% vs. 70.39%±7.98%,Plt;0.01), the myocardial infarction areas reduced significantly (795%±6.32% vs. 1568%±10.36%,q=8.680, Plt;0.01). 〖WTHZ〗Conclusion The protective effect of IPC on I/R elderly rat hearts has weakened. The enhanced IPC is able to regain the protective effect of IPC on elderly rat hearts.

    Release date:2016-08-30 06:06 Export PDF Favorites Scan
  • 严重左心室功能不全冠心病患者的外科治疗

    目的总结有严重左心室功能不全[左心射血分数(LVEF)≤0.35]冠状动脉粥样硬化性心脏病(冠心病)患者行冠状动脉旁路移植术(CABG)的临床经验。方法18例有严重左心室功能不全的冠心病患者冠状动脉造影均显示为3支血管病变,在体外循环下行CABG,采用左乳内动脉18支与前降支吻合,采用桡动脉11支及大隐静脉26支与其它血管吻合。所有患者术前、术后均行正电子发射断层18F-脱氧葡萄糖显像(18F-FDGPET)检查,以判定心肌的存活状况。结果手术死亡1例,死于心室颤动。12例使用主动脉内球囊反搏(IABP),术后二次气管内插管3例。随访17例,随访时间14~26个月,所有患者心功能较术前均有不同程度的改善,LVEF(0.51±0.13)较术前(≤0.35)增大。2例出院后出现心绞痛复发。结论CABG是治疗严重左心室功能不全冠心病患者的有效治疗方法,其效果取决于存活心肌的多少及可再血管化的目标血管的数量。术中良好的心肌保护,积极应用IABP及护心通是手术成功的关键。

    Release date:2016-08-30 06:25 Export PDF Favorites Scan
  • 冠状动脉瘘27例

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
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