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find Author "李畅" 6 results
  • The Diagnosis and Treatment of McKittrick-Wheelock Syndrome

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  • 胃肠吻合术联合术后化疗治疗不能根治切除伴幽门梗阻的进展期胃癌

    目的探讨不能根治性切除伴幽门梗阻进展期胃癌行胃肠吻合结合术后化疗的效果。方法选择 37 例符合纳入及排除标准的病例,进行回顾性研究,分析手术相关数据,化疗效果和生存情况。结果手术后 4 周复查胃出口梗阻评分系统(GOOSS)的评分、体质量指数(BMI)、血红蛋白及白蛋白指标,除 BMI 外,其他 3 项指标均明显好转,与术前比较差异具有统计学意义(P<0.001,P=0.027,P=0.08)。化疗后肿瘤病灶缩小 23 例(62.2%),无明显变化 11 例(29.7%),肿瘤较前增大 3 例(8.1%)。化疗后转移淋巴结缩小或消失 17 例(68.0%),6 例(24.0%)无明显变化,2 例(8.0%)淋巴结较前增大。化疗前有腹水 20 例(54.1%),化疗后腹水减少甚至消失 17 例(85.0%),腹水无明显变化 3 例(15.0%),无腹水增多者。本组 37 例患者中获随访 35 例,随访率为 94.6 %;随访时间 6~30 个月,平均 17.8 个月;本组患者的生存时间 6~30 个月,中位生存时间 11.6 个月。结论对于不能根治性切除的合并幽门梗阻的进展期胃癌,胃肠吻合术后联合化疗可获得较满意的治疗效果。

    Release date:2019-11-25 02:42 Export PDF Favorites Scan
  • Efficacy of Infliximab for Injection in Treatment of Refractory Ulcerative Colitis

    目的 评价注射用英夫利西单抗治疗难治性溃疡性结肠炎(UC) 的疗效。方法 回顾性分析2009年10月至2012年10月期间,在中国医科大学附属第四医院肛肠外科住院并接受注射用英夫利西单抗治疗的9例中重度激素难治性UC患者的临床疗效。结果 经注射用英夫利西单抗治疗后,7例中度UC患者中,1例完全缓解,4例有效,1例疗效不详,1例无效;2例重度UC者中,1例有效,1例无效。临床缓解及治疗有效的6例患者的血红蛋白水平较治疗前上升,红细胞沉降率及C反应蛋白水平均下降。3例具有肠外表现者的肠外症状均得到改善。结论 对于激素抵抗或激素依赖的中重度UC患者,注射用英夫利西单抗可以有效缓解患者的临床症状。

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  • 凝血机制异常致阑尾术后出血2例报道

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  • 肠梗阻导管治疗结直肠癌手术后早期炎症性肠梗阻

    目的探讨肠梗阻导管在非手术治疗结直肠癌术后早期炎症性肠梗阻(EPISBO)中的临床效果。方法选取 2013 年 1 月至 2019 年 7 月期间符合诊断标准的 68 例 EPISBO 患者为研究对象,根据治疗方法的不同分为应用鼻胃管的常规治疗组(简称鼻胃管组)37 例和应用肠梗阻导管治疗组(简称导管组)31 例,观察 2 组患者的日均胃肠减压量、总胃肠减压量以及肠功能恢复时间。结果2 组间手术方式、手术时间、麻醉时间和手术后梗阻发生时间比较差异均无统计学意义(P>0.05);导管组的日均胃肠减压量和总胃肠减压量均多于鼻胃管组(P<0.001);导管组的恢复肛门排气时间(P<0.001)和恢复排便时间(P=0.001)均短于鼻胃管组。结论应用肠梗阻导管治疗结直肠癌手术后 EPISBO,可以提高肠管减压效果,加快肠功能恢复,进而缩短治疗时间。

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  • Single Utility Port Video-assisted Thoracoscopic Lobectomy for Benign Pulmonary Diseases

    ObjectiveTo evaluate the safety and efficacy of single utility port video-assisted thoracoscopic lobec-tomy in the treatment of benign pulmonary diseases. MethodsFrom January 2011 to April 2014, 48 patients with benign pulmonary diseases underwent single utility port video-assisted thoracoscopic lobectomy in the First Affiliated Hospital of Soochow University. The patients included 21 males and 27 females, with their mean age of 47.4 years. There were 5 patients received right upper lobectomy, right middle lobectomy in 5 patients, right lower lobectomy in 5 patients, left upper lobectomy in 8 patients, and left lower lobectomy in 20 patients. the clinical outcomes included operation time, intraoperative blood loss, chest drainage duration, postoperative hospital stay and postoperative complications. ResultsThere were 2 patients conversion to open surgery. The average operation time was 147.2±50.4 min, intraopera-tive blood loss was 160.2±25.3 ml, postoperative chest drainage duration was 4.8±2.8 d, postoperative hospital stay was 7.4±1.9 d. There was no hospital death or serious postoperative complications. Postoperative pathological diagnosis showed bronchiectasis in 17 patients, inflammatory pseudotumor in 11 patients, tuberculosis in 9 patients, aspergillosis in 4 patients, pulmonary sequestration in 3 patients, bronchogenic cyst in 2 patients, pulmonary abscess in 1 patient, and hamartoma in 1 patient. No long-term complications were noticed in 48 patients during a mean follow-up of 6 months. ConclusionSingle utility port video-assisted thoracoscopic lobectomy is safe and feasible in the treatment of benign pulmonary diseases.

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