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find Author "李莎" 5 results
  • 心脏直视手术后早期心肌顿抑的诊断与治疗

    目的探讨心脏瓣膜置换术后早期心肌顿抑的诊断及治疗以及其所引起的低心排血量综合征(LCOS)的诊疗。 方法回顾性分析我院 2011 年 1 月至 2018 年 3 月期间 42 例心脏瓣膜置换术后早期出现心肌顿抑导致 LCOS 患者的临床资料,其中男 19 例、女 23 例,年龄 38~55(47.91±5.51)岁。术前左心室舒张末期内径(LVEDD)3.8~6.5(5.3±0.9)cm,左心室射血分数(EF)45%~60%(51.2%±5.3%);冠状动脉粥样硬化性心脏病筛查均为阴性;其中单纯主动脉瓣置换 12 例,二尖瓣置换合并三尖瓣成形 15 例,二尖瓣和主动脉瓣置换 15 例。 结果42 例患者均在术后早期[10~24(18.83±4.24)h]出现无明确原因的 LCOS,大剂量肾上腺素[0.06~0.10 μg/(kg·min)]和去甲肾上腺素[0.1~0.5 μg/(kg·min)]治疗无效而加用主动脉内球囊反搏(IABP)治疗,其中 25 例患者行肾脏替代治疗(CRRT)。IABP 辅助时间 3~10(5.16±1.95)d,CRRT 治疗时间 22~61(42.17±10.75)h。40 例患者痊愈出院,2 例患者院内死亡,1 例死于脓毒血症,1 例患者死于恶性心律失常。 结论心脏瓣膜置换术后早期出现心肌顿抑引起病情突变恶化,如能早期诊断、早期治疗,将取得好的临床结果。IABP 可以减轻心脏负荷,增加冠状动脉灌注,改善循环,有助于患者渡过心肌顿抑期;CRRT 可以改善 LCOS 患者内环境,减轻肾脏负担。两者是成功救治此类患者的重要手段。

    Release date:2019-03-01 05:23 Export PDF Favorites Scan
  • Efficacy of restrictive bare stent in the treatment of acute Stanford type A aortic dissection

    ObjectiveTo observe the efficacy of restrictive bare stent released on the distal end of the trunk of Stanford type A aortic dissection. Methods The clinical data of 22 patients with Stanford type A aortic dissection requiring aortic arch replacement and trunk surgery and selected for restrictive bare stent placement from November 2016 to February 2018 in our hospital were retrospectively analyzed. Among them, there were 19 males and 3 females, aged 34-68 (49.72±8.05) years. The bare stent was released in the descending thoracic aorta, and the stented elephant trunk was placed in the bare stent. The aortic computerized tomography angiography was reviewed before discharge and the stent position and complications were observed. ResultsOne patient failed to be implanted with bare stents due to a greater resistance and prolapse during implantation. Bare stents were successfully implanted in the remaining 21 patients. One patient died of large-area cerebral infarction after surgery and one patient suffered paraplegia. Twenty patients who survived and successfully implanted bare stents were followed up at regular intervals for 4-21 (13.00±6.14) months. No stroke or death occurred during the follow-up. The computerized tomography angiography showed good stent morphology and position, and no displacement or type Ⅲ endoleak. No stent graft-induced new entry was found. ConclusionAs an adjunct to stented elephant trunk, the use of restrictive bare stents can reduce the possibility of recurrence of a distal stent fracture, significantly expand the narrowest segment and true lumen caliber near the endoluminal graft. Aortic remodeling works well.

    Release date:2019-07-17 04:28 Export PDF Favorites Scan
  • Device and method for evaluating the performance of dry electrode for fabric surface bioelectricity

    In order to quantitatively evaluate the performance of dry electrode for fabric surface bioelectricity, a set of active measuring devices that can simulate electrocardiosignal has been developed on the basis of passive system by our group. Five Ag/AgCl fabric dry electrodes were selected to test and evaluate the devices. The results show that the deviation ratios of peak time interval of the five electrodes are all less than 1%. The maximum voltage amplitude decay rate is 7.2%, and the noise amplitudes are lower than 0.004 mV. The variable coefficient of peak time offset is less than 8%. The variable coefficient of voltage amplitude is less than 2%. The variable coefficient of noise amplitude is less than 10%. Research shows the devices has good repeatability and stability in measuring the simulated electrocardiosignal. The active measuring devices proposed in this paper can provide a new method for performance evaluation and standard formulation of surface bioelectricity dry electrode.

    Release date:2019-06-17 04:41 Export PDF Favorites Scan
  • Interventional Treatment for the Patients with Type 2 Diabetes Combined with Vascular Lesions of Lower Extremities

    【摘要】 目的 探讨2型糖尿病合并下肢血管病变血管内介入治疗的临床意义。 方法 2009年1-5月对4例2型糖尿病合并下肢血管病变患者,根据血管狭窄情况选择不同介入治疗方式,行下肢动脉造影及动脉球囊扩张或支架成形术。 结果 4例患者均有表现静息痛及间歇性跛行,下肢血管超声显示糖尿病下肢动脉有不同程度的斑块、狭窄与血栓形成,病变累及下肢股动脉、髂动脉及胫前、足背动脉。介入治疗后患者下肢血管灌注得到明显改善,静息痛及间歇性跛行明显改善,皮温改善,需要截肢患者截肢平面显著降低。 结论 通过下肢血管DSA造影检查,准确了解糖尿病患者下肢血管的阻塞部位及程度,在保守治疗基础上选择不同方式的介入治疗,有助于下肢血管病变的明显改善。【Abstract】 Objective To investigate the clinical significance of intervention therapy for patients with type 2 diabetes combined with vascular lesions of lower extremities. Methods From January to May, 2009, four diabetic patients with vascular lesions of lower extremities were examined by Doppler ultrasonography and digital subtration angiography (DSA). All patients were treated by percutaneous transluminal angioplasty (PTA) or stenting therapy. Results Stenoses and obstruction of lower extremity blood vessels were observed in all patients. After intervention therapy, vascular perfusion of lower extremities was improved and signs of rest pain and intermittent claudication were relieved; the skin temperature was improved, and the amputation level was apparently decreased. Conclusion It suggests that DSA is effective in judging extend and location of blood vessel stenosis,and the interventional treatment could lead to a satisfying prognosis.

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  • Prognostic Factors of Hospitalized Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

    Objective To investigate the prognostic factors related to in-hospital mortality in patients with acute exacerbation of chronic obstructive pulmonary disease ( AECOPD) . Methods A prospective cohort study was carried out in AECOPD patients admitted in three district general hospitals of Jiangyou city, Sichuan province from February 2007 to February 2008. The clinical and epidemiological data at admission and all-cause death in hospital were recorded. The in-hospital mortality rate and potential determinants of mortality of AECOPD were analyzed using Logistic regression method. Results 257 AECOPD inpatients with AECOPD were recruited into the cohort study. The in-hospital mortality rate was 5.84% (15/257) . Univariate analysis showed in-hospital mortality was significantly associated with age, FEV1% pred, arterial oxygen tension ( PaO2 ) , arterial oxygen saturation ( SaO2 ) , pH, and Charlson’s complication index. Multivariate logistic regression model showed that lower arterial oxygen tension ( OR 4.775;95%CI 1.545 ~14.757; P =0.007) and higher Charlson’s complication index ( OR 4. 608; 95% CI 1. 330 ~15. 966; P =0. 016) were significantly associated with in-hospital mortality after adjustment by age. Conclusion For in-patients with AECOPD, PaO2 and Charlson’s complication index are independent risk factors associated with in-hospital mortality.

    Release date:2016-09-13 03:46 Export PDF Favorites Scan
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