Objective To investigate the MRI characteristics of the tumor of optic pathway and damage degree of visual function. Methods Analysis of 119 cases surgically and pathologically proved tumor suffering from optic pathway was carried out retrospectively. The patients included:36 ones with tumors in anterior segment of optic pathway,70 ones in middle segment of optic pathway,and 13 ones in posterior segment of optic pathway. The MRI examination series were transverse T-1WI SE,transverse and coronal T-2WI TSE,coronal T-2WI SPIR,and transverse,sagittal,coronal T-1WI SE after Gd-DTPA enhancement. Results The tumors of optic pathway included:the primary tumors of the optic pathway and the tumors of any other part of the body which invaded the optic pathway. There was a special MRI feature on the each tumor suffering from optic pathway,but the pituitary adenoma which affects visual function was the most common tumor. Conclusion MRI is an effective method in the diagnosis of optic-pathway tumor. (Chin J Ocul Fundus Dis, 2002, 18: 101-103)
The studies of immunohistochemistry, histochemisu3r and electron microscopy in 50 patients with retinoblastoma were carried out. Our results show that retinoblastoma origin from primitive retinal neuronal cells that can differentiate into nmture neuron (including retinal photoreeeptor) and glial cells.The glial component in the retinoblastoma is mainly reactive glial proliferation.There is a good prognosis in the patients with retinoblastoma in which there are a lot of differiation areas and glial proliferation. （Chin J Ocul Fundus Dis,1993,9:193-197）