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find Author "杨思远" 4 results
  • 心脏机械瓣置换术后使用维生素K1过敏反应一例

    Release date:2016-08-30 06:24 Export PDF Favorites Scan
  • 58例穿透性心脏损伤的临床分析

    目的分析穿透性心脏损伤(PCT)患者的临床特点以及诊治中应注意的问题。方法对13家医院2002年1月至2004年7月的58例PCT患者的临床资料进行回顾性分析。按急诊时临床表现、损伤结局和术前是否进行辅助检查分为临床型和亚临床型,生存组和死亡组,检查组和未检查组三种不同分组,结合临床数据和创伤评分数据对各组的临床分析进行统计学处理。结果PCT发病率仍较高,刀伤是主要致伤原因。临床型患者入院时循环状况更差,损伤严重度更重;死亡组损伤程度重,院内术前时问短,失血休克型患者死亡率更高;检查组院内术前时间更长,能提供确诊线索的价值有限。结论临床分型对PCT患者的临床救治具有很好的指导作用,辅助检查的作用有限,缩短院内术前时间是提高抢救患者成功率的关键。

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • Efficacy of minimally invasive transthoracic closure of atrial and ventricular septal defects

    Objective To evaluate the efficacy and safety of transthoracic minimally invasive occlusion operation for the treatment of congenital atrial and ventricular septal defects. Methods The clinical data of 88 patients who underwent surgical occlusion operation from December 2015 to February 2017 were summarized. There were 52 males and 36 females, aged 6.8±7.5 years ranging from 1.6 to 24.0 years. All the patients were followed up by ultrasound and electrocardiogram at postoperative 3, 6 and 12 months. The efficacy of minimally invasive thoracotomy was analyzed by statistical methods. Results The patients were followed up for 3-15 (6.8±2.3) months, and the follow-up rate was 92.0%. Ultrasound showed occluder fixed well and no residual shunt, valve regurgitation, thrombosis or other complications occurred. The heart was reduced, the ejection fraction was greater than 55%, and heart function rating for all patients was grade Ⅰ. Conclusion Transthoracic mini-invasive surgical occlusion of atrial and ventricular septal defects is safe and effective. The short and middle-term effect is satisfying. It can be widely used in clinical, but multi-center and long-term follow-up and assessment still need to be carried out.

    Release date:2018-07-27 02:40 Export PDF Favorites Scan
  • The relationship between neutrophil elevation and early neurological deterioration after thrombolysis in patients with ischemic stroke

    ObjectiveTo explore the relevance of an increase in neutrophil count and early neurological deterioration (END) after intravenous thrombolysis in patients with acute ischemic stroke.MethodsA retrospective study was conducted on the patients who received thrombolysis treatment of alteplase within 4.5 hours after onset between January 2017 and November 2018. Based on the existence of END, the patients were divided into the END group and the non-END group. Univariate and multivariate logistic regression, and receiver operating characteristic curves were used to analyze the relevances between END and the indexes such as neutrophil count, lymphocyte count, and neutrophil to lymphocyte ratio (NLR) after thrombolysis. Paired sample t test and Wilcoxon signed-rank test were used to compare the changes of neutrophil and lymphocyte before and after thrombolysis.ResultsA total of 187 patients were included, including 48 in the END group and 139 in the non-END group. Before thrombolysis, the differences of total protein (t=2.130, P=0.035) and albumin (t=2.777, P=0.007) between the two groups were statistically significant, but the differences in other clinical indexes between the two groups were not statistically significant (P>0.05). After thrombolysis, white blood cell count, neutrophil count, NLR, fibrinase degradation product, baseline and change of National Institute of Health Stroke Scale score, proportion of cardiogenic embolism, degree of responsible vascular stenosis and anterior circulation cortical infarction site were all higher in the END group than those in the non-END group (P<0.05). The total protein, albumin, lymphocyte count and prealbumin in the END group were lower than those in the non-END group (P<0.05). Neutrophil in the END group increased significantly (Z=−2.314, P=0.021) after thrombolysis. Neutrophil count [odds ratio=1.288, 95% confidence interval (1.069, 1.552)] was one of the independent influencing factors of venous thrombolysis END, and the specificity was the highest (the sensitivity was 62.5%, and the specificity was 71.9%).ConclusionsAfter thrombolysis, elevated neutrophil count has some relevance to END. Dynamic monitoring on neutrophil count after intravenous thrombolysis treatment can predict the occurrence of END.

    Release date:2019-06-25 09:50 Export PDF Favorites Scan
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