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find Author "杨春梅" 4 results
  • Clinical Efficacy of Sphincter-retaining and Loose-seton Therapy in Treating Patients with High Perianal Abscess

    目的 探讨保留括约肌虚挂线法治疗高位肛周脓肿的临床疗效。 方法 2009年10月-2010年10月采用随机对照试验,对52例高位肛周脓肿患者施行手术治疗,其中保留括约肌虚挂线法(治疗组)26例,切开挂线引流法(对照组)26例。对两组患者术后6个月肛瘘发生率、切口愈合时间、术后1~15 d每晚疼痛视觉模拟评分(VAS)和术后6个月痊愈患者肛门功能后遗症发生率进行比较。 结果 术后6个月,治疗组和对照组肛瘘发生率分别为4.0%和3.8%,差异无统计学意义(P>0.05)。术后7~15 d治疗组VAS评分均低于对照组,差异有统计学意义(P<0.05)。两组切口愈合时间分别为(19.05 ± 6.71)d和(21.42 ± 8.40)d,差异有统计学意义(P<0.05)。术后6个月治疗组痊愈患者肛门功能全部正常,对照组后遗症发生率为12.0%,两组比较差异有统计学意义(P<0.05)。 结论 保留括约肌虚挂线治疗在术后疼痛、切口愈合时间和保护肛门功能等方面明显优于切开挂线引流治疗,是一种治疗高位肛周脓肿较为理想的方法。

    Release date:2016-09-08 09:14 Export PDF Favorites Scan
  • 药物临床试验中的几个重要环节

    我国对新药临床研究有严格的审批制度。临床试验以前,需要一系列有关药学、药效、毒理、动物药代动力学等试验结果和文献资料为药物进入临床研究提供充分的理由和依据,保证进入临床试验时受试者得到最大的效益,并将可能遇到的风险降到最低限度,最大程度保护受试者的权益。安全和健康必须高于对科学和社会利益的考虑,因此规范的临床试验尤为重要。这就要求临床试验的各个环节都必须按照标准操作规程进行,且在科学与伦理道德两方面都合格,既要保护受试者的权益,又要保证其安全。

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  • Clinical Study on Divided Excision and Plastic Combined with Procedure for Prolapse and Hemorrhoids in Treatment for Circular Mixed Hemorrhoids

    Objective To investigate the clinical curative effect of divided excision and plastic combined with procedure for prolapse and hemorrhoids (PPH) in treatment for circular mixed hemorrhoids. Methods Clinical observation on 120 patients with circular mixed hemorrhoids between May 2007 and May 2008 treated by divided excision and plastic combined with PPH was carried out. Results The mean hospital stay after operation was 7.6 d. The wound healing average time was 11.9 d. The incidence rate of postoperative urinary retention was 5.8% (7/120). Average scores of pain in 3 d after operation: 5.3 points (1-8 points) on day 1, 3.6 points (2-9 points) on day 2, 2.2 points (1-8 points) on day 3. All patients were followed up for 12 months, there were 3 cases of hematochezia, 1 case of prolapse, and 1 case of remained abnormal outgrowth skin; the anus function was normal in all cases without anal stricture or tightening feeling. Conclusions Divided excision and plastic combined with PPH can better treat circular mixed hemorrhoids. This operation can not only completely clear the lesions, but also repair and reconstruct the anus and anal canal, protect its size and function. It is an ideal operation for treatment for circular mixed hemorrhoids.

    Release date:2016-09-08 10:49 Export PDF Favorites Scan
  • Clinical Study of Curing Rectocele by Divided Plastic Tightening and Constricting Operation

    【摘要】目的 探讨分段整形提缩注射术治疗脱肛痔的临床疗效。方法 175例重度环状痔, 沿肛缘弧形切除结缔组织外痔以整形肛门, 再于结扎痔核基底及其上端黏膜下层注射消痔灵注射液,并进行疗效观察。结果 术后肛周水肿(72 h)、疼痛(24及72 h)明显减少; 术后4周临床治愈145例,好转23例,总有效率为96.0%; 所有患者均随访3~6个月,未见复发。结论 选择分段整形提缩注射术既比较彻底地去除了痔核使之不易复发,又整形了肛门,保护其大小和功能, 该术式可成为治疗脱肛痔的较理想术式。

    Release date:2016-09-08 11:54 Export PDF Favorites Scan
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