ObjectiveTo carry out an investigation on the life quality of amputees in the “5·12” Wenchuan earthquake before and after rehabilitation of one year (short term), three year (intermediate term) and five year (long term) and find out the best program of recovery. MethodsIn September 2008, 52 patients who were treated in the higher-level hospital and came back to the Second People’s Hospital of Mianzhu City for rehabilitation were divided into two groups: group A and B with 26 patients in each. Phased rehabilitation program was adopted for group A while traditional program was chosen for patients in group B. “The Personal Information Table of Amputees of Deyang City” and The Life Quality Measurement Table of World Health Organization were chosen as the research tools before the program and one year, three years and five years after the program. ResultScores of the life quality of both groups showed a general rising tendency, while group A was higher than group B in each single phase, especially in the longterm one. For positive feeling, group A got a score of 193.0±12.3 and group B got 126.0±11.2; for ability to work, group A had a score of 62.0±5.2 and group B had 41.0±2.3; for life satisfaction, group A achieved 150.0±2.1 and group B achieved 101.0±6.2; for ability of action, the score of group A was 17.0±2.6 and group B was 11.0±5.2. The differences were statistically significant (P ＜ 0.05) . ConclusionCompared with conventional rehabilitation program, phased rehabilitation program can better enhance and consolidate the amputees’ quality of life and promote their returning to family and society, which can make up for the deficiency of the existing rehabilitation programs and is worth popularization and application.
目的选择能够早期反映同种异体原位肝移植术后他克莫司(FK506)对患者肾功能损伤的灵敏指标。方法回顾性分析我院自2000年2月至2005年5月的15例肾功能正常的肝移植患者的临床资料，重点分析其尿α1微球蛋白（α1MG）和微量白蛋白（mAlb）以及血肌肝（Cr）和尿素氮(BUN)与FK506血药浓度之间的关系。结果15例肝脏移植患者，尿α1MG及mAlb含量与FK506血药浓度呈正相关（r=0.939,P＜0.005; r=0.893, P＜0.05）， 血Cr及BUN与FK506血药浓度无相关性(r=0.490,Pgt;0.05； r=0.382,Pgt;0.05)。结论尿α1MG和mAlb可作为反映肾功能损伤的早期的灵敏指标，有利于监测肝移植术后FK506的理想全血浓度，能够为临床早期诊断和治疗肾功能损伤提供参考指标。