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find Author "毛文君" 3 results
  • Actuality Evaluation and Strategy Research of Mental Health Service in Chengdu City

    Objective To raise policy suggestions for public health bureaus by analyzing the mental health service in Chengdu City in 2004. Methods We applied descriptive methods to analyze the mental health service. Results The mental health resources in Chengdu City were insufficient and the utilization rate of health resources was low. Conclusions Strategies to improve this may include setting up mental health management sections; increasing the funds for health service; strengthening professionals training; exploiting the service field of relevant specialties and developing community mental health.

    Release date:2016-09-07 02:14 Export PDF Favorites Scan
  • 基因多态性对抗抑郁药物疗效的影响

    【摘要】 抑郁症是临床常见精神疾病之一,疾病负担重,而有相当部分患者对抗抑郁药物治疗无效或效果较差。目前研究发现,抑郁症患者对药物治疗表现出遗传异质性,一些基因位点,如五羟色胺转运蛋白基因、五羟色胺2A受体、色氨酸羟化酶基因等,可能与抗抑郁药物疗效相关。本文总结了抗抑郁药物疗效相关基因多态性的研究现状及进展,对这些基因的深入阐释有助于在将来研发更为有效的药物,为抑郁症患者提供遗传背景个体化的治疗。

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • A Control Study to the Free Treatment of Schizophrenics from Community

    摘要:目的: 观察免费治疗社区精神分裂症患者的疗效。 方法 :纳入贫困家庭精神分裂症患者140例,随机分为免费服药组和对照组,每组70例。随访1年,采用精神分裂症阳性与阴性症状量表(PANSS)\社会功能缺陷量表(SDSS)等评估。 结果 :对实验组与对照组的基线、6个月后及1年后随访的PANSS总分、各因子分、SDSS总分分别进行比较,结果显示基线、6月后均无统计学差异;1年后SDSS总分、PANSS总分、阳性因子分、一般病理因子、思维障碍、偏执因子分差异有显著性;免费治疗组1年后各指标与入组前相比分值降低(P<001)。 结论 :精神分裂症患者免费服药后精神症状缓解明显,同时其社会功能缺陷也得到改善。Abstract: Objective: To observe the effect of the free treatment on schizophrenics from community. Methods : Totally 140 subjects from poor family were divided into the free treated group and the control group at random. They were followed up for 1 year. The treatment effects were evaluated by PANSS and SDSS. Results : There were no significant difference in all examinations at baseline and after 6 months; at the following end point, significant difference existed in the score of SDSS, the total scores of the PANSS, the positive factor, the general pathology factor, the thinking factor and the paranoid ideation factor between two groups. There was decrease in the scores for all examinations in the free treated group. Conclusion : The symptoms of schizophrenics by free treatment relieve significantly, and the social function improves.

    Release date:2016-09-08 10:12 Export PDF Favorites Scan
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