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find Author "江婷" 3 results
  • 肝门部胆管癌扩大根治术患者围手术期护理

    目的:探讨肝门部胆管癌术后的观察和护理技巧。方法:对我科 2006~2008年经手术治疗临床肝门部胆管癌 68 例患者的临床护理做回顾分析。结果:术后3 例因肝功能衰竭死亡;1 例术后10 天并发肺炎死亡; 2 例术后发生大出血死亡,其余在我们的精心护理和指导下分别生存 5 个月~36 个月。结论:密切观察患者生命体征及病情变化,做好引流管护理,加强并发症的观察及护理;是促进患者早日康复、提高生存质量的关键。

    Release date:2016-09-08 09:56 Export PDF Favorites Scan
  • 计划-实施-检查-处理循环法在提高医疗废物正确处理率中的应用及效果

    目的探讨应用计划-实施-检查-处理(PDCA)循环法提高医疗废物正确处理率的可行性。 方法对2013年4月-6月在工作和轮转的医护人员、实习生、保洁人员和在此期间住院的患者及家属医疗废物及生活垃圾的丢弃情况进行定期检查和随机抽查,并运用PDCA进行持续改进,完善和提高医疗废物、生活垃圾的正确处理方式。 结果实施PDCA循环管理法后,医生和护士医疗废物的正确处理率较实施前均有明显改善,两者比较差异有统计学意义(χ2=84.03,P<0.01;χ2=43.10,P<0.01),患者及家属生活垃圾的正确处理率也明显提高,差异有统计学意义(χ2=56.71,P<0.01)。 结论PDCA循环法可在短期内有效地提高医疗废物的正确处理率。

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  • Experimental Study of Epidermal Growth Factor Receptor Antagonist in Treating Chronic Proliferative Cholangitis

    ObjectiveTo investigate the effectiveness of epidermal growth factor receptor antagonist (AG-1478) on chronic proliferative cholangitis (CPC), so as to investigate new treatment approach for hepatolithiasis associated with CPC. MethodsForty-six SD rats were divided into 5 groups: CPC model group (n=10), only made models. AG-1478 treatment group (divided into 3 mg/kg, 6 mg/kg, and 12 mg/kg groups, n=10 per group), the common bile ducts in CPC animal model received an intralumenal administration of AG-1478 at the meantime of modeling, followed by intraperitoneal AG-1478 injection of 1.5 mg/(kg·d) for 7 days. Sham operation group (SO group, n=6). Subsequently, histopathological observation, immunohistochemistry, real time PCR, and Western blot were used to evaluate the mRNA expression and influence of AG-1478 on the hyperplasia (EGFR, ki-67, BrdU, collagen Ⅰ protein) and lithogenic potential (Mucin 5AC) of CPC. ResultsCompared with CPC model group, the expressions of EGFR, ki-67, and BrdU were obviously decreased in the AG-1478 treatment group. Also, the inhibition of hyperplasia of biliary epithelium and collagen fibers were confirmed by histopathological observation. Additionally, the expressions of Mucin 5AC mRNA and collagen Ⅰ protein remarkable decreased in the AG-1478 treatment group (Plt;0.05). Conclusions EGFR inhibitor (AG-1478) could shows inhibitory effectivenss on the CPC-mediated hyperplasia and lithogenic potential, and therefore holds promise as the new treatment approach for CPC.

    Release date:2016-09-08 10:45 Export PDF Favorites Scan
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