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find Keyword "波谱成像" 8 results
  • Quantification of Liver Fat Content by 1H-MR Spectroscopy Imaging at 3.0 T for Therapeutic Evaluation of Fatty LiverPreliminary Study

    ObjectiveTo investigate the feasibility of proton magnetic resonance spectroscopy (1H-MRS) imaging, by which to quantitatively analyze liver fat content for therapeutic evaluation of fatty liver at 3.0 T MRI. MethodsTwenty-six patients who diagnosed with fatty liver were examined with proton MRS at Siemens Trio Tim 3.0 T MRI before treatment and 3, 6 months after treatment, respectively. The water peak, fat peak, water peak area, and fat peak area were detected, and the relative lipid content 1 (RLC1) and relative lipid content 2 (RLC2)were calculated. Fatty liver index (FLI) was referred to the standard which was calculated from triglycerides (TG), gammaglutamyl-transferase (GGT), waist circumference, and body mass index. ResultsThere were significantly different differences of RLC1 and RLC2 among before treatment and 3, 6 months after treatment (Plt;0.05). Compared with before treatment, the RLC1 and RLC2 values significantly decreased on month 3 or 6 after treatment (Plt;0.05). There were positive correlation between RLC1 or RLC2 and FLI (r=0.476, Plt;0.00; r=0.475, Plt;0.001). The intraclass correlation coefficient was more than 0.75 before treatment, the repeatability was better. ConclusionsProton MRS can quantitatively measure liver fat content. It can be reliably used for dynamic monitoring the therapeutic effects for fatty liver. Proton MRS is accurate, and has a good clinical application in dynamically monitoring the progression of fatty liver and evaluating the therapeutic effects of various treatments.

    Release date:2016-09-08 10:45 Export PDF Favorites Scan
  • Differentiation of Chronic Mass-Forming Type Pancreatitis from Pancreatic Carcinoma by Functional Magnetic Resonance Imaging

    Objective To summarize the principle and application of functional MR imaging of pancreatic carcinoma and chronic mass-forming type pancreatitis. Methods Articles about diffusion-weighted imaging (DWI), magnetic resonance spectrum imaging (MRSI) and dynamic contrast-enhanced MR imaging of pancreatic carcinoma and chronic pancreatitis were reviewed and analyzed. Results Functional MR imaging could reflected the differences in molecules diffusion, metabolism and tissue perfusion between pancreatic carcinoma and chronic pancreatitis. Conclusion  As a non-invasive protocol, functional MR imaging can provide useful information in differential diagnosis between chronic mass-forming type pancreatitis and pancreatic carcinoma.

    Release date:2016-08-28 04:08 Export PDF Favorites Scan
  • Clinical Applications of Hepatic 31P-MR Spectrocscopy

    【Abstract】Objective To summarize the principle and clinical applications of 31phosphorus MR spectroscopy(31pMRS). Methods Literatures about 31PMRS in liver were reviewed and analyzed. Results Abnormalities of 31PMRS were found in patients of hepatitis, liver cirrhosis, liver tumor,obstructive jaundice and patients after liver transplantation. Evaluation of 31PMRS is important in diagnosis and treatment of many hepatic diseases. Conclusion As a noninvasive protocol for analyzing the energetic metabolism and biomedical changes in cellular level of living liver, 31PMRS has a wide clinical application.

    Release date:2016-08-28 04:28 Export PDF Favorites Scan
  • Recent Advances on Magnetic Resonance Spectrum Imaging in Diagnosis and Differential Diagnosis of Pancreatic Cancer

    Objective To summary the principle of magnetic resonance spectroscopy imaging and its application progress in diagnosis and differential diagnosis of pancreatic cancer. Methods The newest related literatures of home and abroad were collected and reviewed. Results Magnetic resonance spectroscopy imaging was a technology using the magnetic resonance phenomena and chemical shift phenomena to measure molecular organization. The spectroscopy most commonly used in clinical and scientific research includes 1H, 31P, and 23Na. Conclusion Magnetic resonance spectroscopy as the only approach to noninvasive quantitative provding biochemical information in vivo, has an important significance to the diagnosis and differential diagnosis of pancreatic cancer.

    Release date:2016-09-08 10:24 Export PDF Favorites Scan
  • 磁共振氢波谱技术在肿瘤临床诊疗研究中的进展

    磁共振波谱(MRS)成像技术作为一种无创的功能影像学方法,广泛应用于临床多领域的研究,包括当今研究热点临床肿瘤诊断和疗效评价。现以MRS技术中最常用的氢质子波谱(1H-MRS)为对象,由成像原理、检测意义入手,就1H-MRS技术在肿瘤诊疗研究中的新进展作一综述,以客观评估该技术在临床肿瘤诊断和疗效评价中的应用。

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  • 特发性震颤的磁共振功能成像进展

    特发性震颤(essential tremor,ET)是临床最为常见的神经系统疾病之一,以姿势性或动作性震颤为主要临床表现。磁共振功能成像(functional magnetic resonance imaging,fMRI)是 20 世纪 90 年代以来在传统的 MRI 技术的基础上迅速发展起来的一种新的成像技术。该文就 fMRI 在 ET 中的应用原理、病理生理机制、鉴别诊断以及发展前景等方面进行了综述。

    Release date:2017-05-18 01:09 Export PDF Favorites Scan
  • Application of the dynamic contrast enhanced MRI combined with magnetic resonance spectroscopy in diagnosis of prostate cancer

    Objective To investigate the application of the dynamic contrast enhanced MRI (DCE-MRI ) combined with magnetic resonance spectroscopy (MRS) in the diagnosis of prostate cancer. Method A total of 60 patients with prostate cancer and 60 patients with benign prostatic hyperplasia diagnoses in Sichuan Cancer Hospital from January 2011 to January 2014 were included as prostate cancer group and proliferative group respectively. Sixty healthy individuals during the same period were included as the control group. We used Siemens Avanto 1.5 T high field superconducting MRI for DCE-MRI scan and MRS scan. After the MRS scan was finished, we used the workstation spectroscopy tab spectral analysis. Eventually we got the crest lines of prostate metabolites choline (Cho), creatine (Cr) and citrate (Cit). Then we calculated Cho/Cit, (Cho+Cr)/Cit and their average. Results Comparing the signal value in 21 seconds, 1 minute, 2 minutes of DCE-MRI, the differences among the three groups were statistically significant (P<0.05). Comparing the results of spectral analysis, the differences among the three groups were statistically significant (P<0.05). The sensitivity was 89.67%, the specificity was 95.45% and the accuracy was 94.34% when using DCE-MRI combined with MRS. Conclusion DCE-MRI combined with MRS greatly improves the sensitivity, specificity and accuracy of the diagnosis of prostate cancer; it has a great application value in the diagnosis of prostate cancer.

    Release date:2017-07-21 03:43 Export PDF Favorites Scan
  • 多模态磁共振成像在儿童癫痫中的研究应用

    癫痫是常见的神经系统疾病,病理生理机制复杂,一部分患者难以找到病因。核磁共振成像(MRI)是癫痫诊断,尤其在癫痫灶定位方面的一项重要的影像学技术。随着功能磁共振技术(fMRI)的不断进步,在癫痫的诊治中日益突出,可以从生化微结构水平及脑网络方面探讨其发病机制,对明确病因具有重要意义,从而有助于实施个体化精准治疗,文章综述了近年来多模态 MRI 技术在癫痫领域的应用。

    Release date:2018-09-18 10:17 Export PDF Favorites Scan
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