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find Keyword "消化道出血" 36 results
  • Effectiveness and Safety of China-Made Omeprazole in Treating Acute Non-Variceal Upper Gastrointestinal Bleeding: A Meta-Analysis

    Objective To systematically evaluate the effectiveness and safety of China-made omeprazole in treating acute non-variceal upper gastrointestinal bleeding. Methods Such databases as PubMed, MEDLINE, Springer, The Cochrane Library, CNKI, VIP, CBM and WanFang data were searched to collect the randomized controlled trials (RCTs) about China-made omeprazole in treating acute non-variceal upper gastrointestinal bleeding, and the references of included studies were also retrieved. The retrieval time was from inception to December 2012. Two reviewers independently screened the literature according to the inclusion and exclusion criteria, extracted the data, and assessed the quality, and then the meta-analysis was conducted by using RevMan 5.1 software. Results A total of 11 RCTs were included. Among all 1 075 patients, 544 were in the treatment group, while the other 531 were in the control group. The results of meta-analysis showed that, there were no significant differences in the total effective rate (OR=0.68, 95%CI 0.35 to 1.33, P=0.26) and safety (RR=1.33, 95%CI 0.45 to 3.91, P=0.96) between the China-made omeprazole and imported omeprazole. Conclusion China-made omeprazole is effective and safe in treating acute non-variceal upper gastrointestinal bleeding in comparison with the imported omeprazole.

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  • Evidence-Based Treatment for a Patient with Obscure Gastrointestinal Bleeding

    Objective  To discuss the common clinical problems and make the individualized treatment for a patient with obscure gastrointestinal bleeding by means of evidence-based medicine, so as to ultimately control the symptoms and reduce the mortality. Methods  After the clinical problems were put forward, the systematic reviews and randomized controlled trials (RCTs) were collected in The Cochrane Library (online), MEDLINE, EMBase, SCIE and CNKI databases, from the date of their establishment to 2010. The treatment protocol was made by combining the assessment of evidence with the willingness of both patient and relatives. Results  A total of 30 RCTs and 5 systematic reviews were identified. A rational diagnostic and therapeutic plan was made upon a serious evaluation of the data and willingness of patients. The Mickel’s diverticulum was found through capsule endoscopy, which was then locally excised under laparoscopy. After a 6-month follow-up, the plan proved to be optimal. Conclusion  The treatment efficacy in diagnosed obscure gastrointestinal bleeding has been improved by adopting an individualized treatment plan according to evidence-based methods.

    Release date:2016-08-25 02:39 Export PDF Favorites Scan
  • Efficiency Analysis of Somatostatin for the Treatment of Peptic Ulcer Complicated by Upper Gastrointestinal Bleeding

    目的:比较国产生长抑素与进口生长抑素治疗消化性溃疡出血的经济效果。方法:将120例消化性溃疡伴出血的患者随机分成国产生长抑素及进口生长抑素组,分别给予国产生长抑素、进口生长抑素治疗3天,观察疗效,并进行药物经济学评价。 结果: 国产生长抑素、进口生长抑素治疗上消化道出血成本分别为558元和4116元,有统计学差异(P<005);有效率分别为925%和968%,无统计学差异 (Pgt;005),成本—效果比分别为60324和425207,有统计学差异(P<005)。结论: 从药物经济学角度分析,国产生长抑素治疗消化性溃疡出血较进口生长抑素更为经济。

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
  • Clinical Application on Transjugular Intrahepatic Portosystemic Shunt for Treatment of Repeated Bleeding after Splenectomy with Portal Hypertension

    目的 总结经颈静脉肝内门体静脉分流术(TIPS)治疗未合并肝癌的门静脉高压症患者行脾切除术后反复上消化道出血的疗效。方法 对未合并肝癌或胆管癌的门静脉高压症合并上消化道大出血患者行脾切除术后复发出血患者行TIPS术治疗,并随访1~5年(平均3.2年)的资料进行总结与分析。结果 36例脾切除术后再出血者行TIPS术, 手术均获成功,围手术期死亡率为2.78%(1/36),死亡原因是肝性脑病。随访期间患者术后再次复发出血率为5.71%(2/35)。结论 TIPS对脾切除治疗门静脉高压症后反复出血病例的效果良好。

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  • Analysis on Effect of Liver Transplantation in Treatment of Upper Gastrointestinal Hemorrhage in Patients with Portal Hypertension

    Objective To explore the feasibility and safety of liver transplantation (LT) in treatment of upper gastrointestinal hemorrhage in patients with portal hypertension, and to compare the therapeutic effects with conventional operation (CO). Methods The clinical data of 303 patients with bleeding portal hypertension from Feb. 2009 to Feb. 2012 in the department of hepatobiliary and pancreatic surgery of First Affiliated Hospital of Zhejiang University were retrospectively analyzed. One hundred and one patients received LT procedure (LT group), whereas the other 202 patients received CO procedure (CO group). Postoperative follow-up period was 8-44 months (average 26 months). Results Liver function before operation in CO group was significantly better than that in LT group(P<0.01). The mortality of CO group and LT group were 7.4%(14/189) and 3.0%(3/101, P=1.00), respectively. The rebleeding rate of patients underwent LT was 2.0%(2/101), significantly lower than that of CO group 〔9.5%(18/189), P<0.05〕. The vanish rate of esophagogastric varice in patients underwent LT was 86.1%(87/101), significantly lower than that of CO group 〔54.5%(86/189), P<0.01〕. Conclusions LT treatment for bleeding portal hypertension is feasible and safe. Patients with good liver function despite hemorrhage history may be managed satisfactorily with conventional surgery. LT is the only curative treatment for patients with portal hypertension in end-stage liver disease.

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  • Current Status and Perspectives in The Management of Portal Hypertension

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  • Treatment for Upper Gastrointestinal Bleeding Related to Stress Ulcer

    目的总结外科手术后应激性溃疡大出血的临床特点和治疗经验。方法回顾分析1997~2003年期间我院治疗的32例应激性溃疡大出血患者的临床资料。结果28例患者采用非手术治疗,其中12例患者接受急诊胃镜检查; 手术治疗4例。本组患者总的治愈率为87.50%,死亡率为15.62%。结论急诊胃镜检查有助于明确诊断及止血治疗,应激性溃疡大出血首选非手术治疗,无效者可选择手术治疗。

    Release date:2016-08-28 04:20 Export PDF Favorites Scan
  • 肠粘膜下血管发育不良致下消化道大出血的诊治(附3例报告)

    Release date:2016-08-29 03:19 Export PDF Favorites Scan
  • 食管癌术后下消化道出血的诊治分析

    Release date:2016-08-30 05:46 Export PDF Favorites Scan
  • 术中胃镜辅助治疗食管癌术后上消化道出血

    目的 总结术中胃镜辅助治疗食管癌术后上消化道出血的临床经验。 方法 回顾性分析2001年3月至2009年3月成都军区总医院6例食管癌手术后上消化道出血患者经胃镜辅助手术治疗的临床资料,其中男5例,女1例;年龄55~78岁,平均年龄64岁。6例食管癌手术后患者均于术后24 h内发生上消化道出血,需再次手术止血,在胃镜辅助下查找出血点,通过直接缝扎、局部药物注射、微波凝固和金属夹进行止血处理,再次手术后观察止血效果。 结果 再次手术后6例患者上消化道出血立即停止,血压回升,均未发生吻合口瘘和胸胃穿孔等并发症,痊愈出院。随访6例,随访时间3个月~1年,随访期间1例死于放、化疗并发症,其余患者均未发生上消化道出血。 结论 胃镜辅助手术治疗食管癌手术后上消化道出血,能准确查找出血部位,通过缝扎、局部药物注射,微波凝固治疗、金属夹止血的应用,控制出血迅速可靠,方法简单、安全。

    Release date:2016-08-30 05:57 Export PDF Favorites Scan
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