摘要:目的：探讨急性重症胰腺炎（SAP）早期不同种类液体复苏对其预后的影响。方法：应用随机对照的方法,分别对2007年12月~2009年10月同期入院的48例SAP患者,随机分成两组,试验组和对照组。试验组第一周内液体复苏采用晶体液和人工胶体（羟乙基淀粉）,对照组采用晶体液,其他治疗方法不变。然后统计其第一周死亡率、ARDS、多器官功能障碍综合征（MODS）发生率,对比两组患者呼吸频率、血氧饱和度和红细胞压积（HCT）差异,以及两组患者肠功能恢复时间、住院时间以及并发症发生率。结果：试验组的液体复苏较对照组显著改善SAP的各项指标（P＜005）。血清乳酸水平（15±05）mmol/L,红细胞压积(HCT)为（324±69）%,ScvO2为（817±152）%,病死率83%,MODS发生率333%,〖HT5”H〗结论:〖HT5”SS〗 SAP早期联合应用晶胶体进行液体复苏可有效恢复循环血容量和防止体液潴留,显著提高其治愈率。Abstract: Objective: To investigate the optimal strategy of fluid resuscitation in the early stage ofsevere acute pancreatitis.〖WT5”HZ〗Methods:〖WT5”BZ〗Fourfyeighs SAP patients who received treatment in our hospital from 12,2007 to 10,2009 were randomly divided into 2 groups (n=24) according to the different amounts of crystal and colloid inthe daily resuscitation,including crystal group,combined group(the ratio of crystal to colloid was 2 to 1).The levels of hematocrit(HCT),saturation of central vein oxygen ( ScvO2 ),serum lactic acid as well as the advent of negative fluid balance the amount of fluid contained in the third space,mortality rate and the incidence of multiple organ dysfunction syndrome(MODS) in different groups were compared.〖WT5”HZ〗Results:〖WT5”BZ〗 Compared with crystal group,all the parameters were significantly improved in combined group(P＜005).HCT in the group of patients was(324±69)%,ScvO2 was (817±152)%,lactic acid was(15±05)mmol/L,mortality rate was 83% and MODS incidence was 333%. Conclusion:In the early stage of SAP,fluid resuscitation by a combination of crystal and colloid could effectively restore blood volume, reduce the amount of fluid contained in the third space and significantly improve the prognosis of SAP.
目的 探讨胆道再次手术的原因和对策。 方法 对1997年12月至2003年12月206例胆道再次手术的原因和术式进行回顾性分析。结果 172例（83.5%）因结石复发和（或）残留主要行胆总管切开取石术、肝叶切除术、胆总管空肠Roux-Y吻合术及胆道镜取石术； 9例（4.4%）胆道恶性肿瘤主要行根治性切除术、内外引流术； 5例（2.4%)胆管损伤及3例（1.5%）十二指肠损伤主要行胆总管断端吻合术、T管引流术、胆肠吻合术、十二指肠修补及造瘘术； 17例（8.3%）因其他原因再手术者主要行胆总管囊肿切除+胆肠吻合术、腹腔引流术、腹腔探查、止血术等。结论 ①胆道再手术主要原因是残留结石和（或）复发； ②为降低胆道再手术率，应强调术前诊断明确、选择正确术式和审慎操作。
的讨论先天性巨结肠的手术治疗。方法回顾106例先天性巨结肠的手术治疗方式及疗效。结果采用改良Duhamel术式治疗先天性巨结肠并发症少，远期排便功能良好。结论改良Duhamel术式适于任何年龄和所有类型的巨结肠，疗效满意。