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find Author "王凤楼" 2 results
  • 肌阵挛与肌阵挛癫痫

    肌阵挛是中枢神经系统所致突然、短暂、电击状(shock like)不随意运动。肌阵挛癫痫定义尚有争议,目前认为可能是涵盖癫痫的电临床意义,累及下行的神经元,此神经元的扩展或颞叶扩充能扳击为明显的痫性活动。肌阵挛可能是多种癫痫综合征的一部分(如青少年肌阵挛、全面强直-阵挛或进行性肌阵挛癫痫),也可能是单独发作表现(如良性肌阵挛癫痫),或是多种癫痫类型之一(如肌阵挛性-不稳定性癫痫)。肌阵挛癫痫分为皮层性肌阵挛、丘脑-皮层性肌阵挛、皮层反射性肌阵挛、阴性肌阵挛、良性家族性皮质性肌阵挛震颤癫痫、进行性肌阵挛癫痫、青少年肌阵挛癫痫。一般传统抗癫痫药物,除丙戊酸、氯硝基安定、苯巴比妥外,其他抗癫痫药物均无效。新型抗癫痫药物已证实左乙拉西坦、托吡酯、唑尼沙胺、吡拉西坦及吡仑帕奈有效,但对不同类型肌阵挛癫痫治疗效果有差异。

    Release date:2021-06-24 01:26 Export PDF Favorites Scan
  • Wavelet entropy analysis for ictal electroencephalogram signals of child absence epilepsy

    The integral and individual-scale wavelet entropy of electroencephalogram (EEG) were employed to investigate the information complexity in EEG and to explore the dynamic mechanism of child absence epilepsy (CAE). The digital EEG signals were collected from patients with CAE and normal controls. Time-frequency features were extracted by continuous wavelet transformation. Individual scale power spectrum characteristics were represented by wavelet-transform. The integral and individual-scale wavelet entropy of EEG were computed on the basis of individual scale power spectrum. The evolutions of wavelet entropy across ictal EEG of CAE were investigated and compared with normal controls. The integral wavelet entropy of ictal EEG is lower than inter-ictal EEG for CAE, and it also lower than normal controls. The individual-scale wavelet entropies of 12th scale (centered at 3 Hz) of ictal EEG in CAE was significantly higher than normal controls. The individual-scale wavelet entropies for α band (centered at 10 Hz) of ictal EEG in CAE were much lower than normal controls. The integral wavelet entropy of EEG can be considered as a quantitative parameter of complexity for EEG signals. The complexity of ictal EEG for CAE is obviously declined in CAE. The wavelet entropies declined could become quantitative electrophysiological parameters for epileptic seizures, and it also could provide a theoretical basis for the study of neuromodulation techniques in epileptic seizures.

    Release date:2018-08-23 05:06 Export PDF Favorites Scan
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