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find Author "王圣" 7 results
  • Diagnosis and Surgical Treatment of Primary Cardiac Malignant Tumors

    Objective To investigate the diagnosis and treatment methods of primary cardiac malignant tumors,so as to improve its’ level of diagnosis and treatment. Methods From April 2004 to June 2008, 19 patients with primary cardiac malignant tumors were diagnosed and treated in the department of cardiac surgery in this hospital. Male 11, Female 8.Age of the patients was 40.7±12.1 years(17-64 years). Preoperative diagnosis were occupying lesion in cardiac, malignant tumors were possible. Complete resections of malignant tumors were achieved by cardiopulmonary bypass (CPB) in 3 cases, and partially resected in 1 case, heart transplantation was performed in 1 case, only biopsies were performed in 5 cases. 9 cases (47.4%) lost the chances of operative treatments. Results There were no operative and hospitalstay deaths. Hospital stay was 10±7 d(9-15 d), all patients were safely discharged from hospital. Two cases suffered from postoperative pericardial effusions,and high temperature happened in 1 patient, these 3 cases recovered by puncture and symptomatic treatment. The pathological diagnosis: leiomyosarcoma in 1case, malignant mesothelioma in 1 case and hemangioendothelial sarcoma in 8 cases. 14 cases (73.7%) were followed up from 1 to 38 months, 14 cases died of tumor recurrence or metastasis, the mortality was 73.7%, 5 cases (26.3%) were failed to be followed up. Conclusion The prognosis of patient with primary cardiac malignant tumor is still poor. Earlier diagnosis and complete surgical removal of the tumor as soon as possible may improve the patients’qualities of lives. 

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • 胸骨下段小切口行非体外循环冠状动脉旁路移植术

    目的 探讨胸骨下段小切口在非体外循环冠状动脉旁路移植术中应用的效果。 方法 回顾性分析 2012 年 6 月至2014 年 12 月前降支单支病变的冠心病患者行胸骨下段小切口非体外循环冠状动脉旁路移植术 19 例的临床资料,其中男 11 例、女 8 例,年龄 59.6(44~68)岁。所有患者均游离左乳内动脉与前降支吻合,其中 1 例因术中探查见第一对角支近端明显粥样斑块且对角支粗大,遂向上延长切口,全胸骨打开,游离大隐静脉行对角支搭桥,近端吻合于升主动脉,术后 1、3、6、12 个月进行随访。 结果 其中 1 例术中转为常规胸骨正中切口手术,其余 18 例手术胸骨下段小切口完成,术中血流动力学稳定,无围术期急性心肌梗死及死亡病例,无乳内动脉损伤、无吻合口漏血及恶性心律失常发生,无大出血、二次开胸止血及切口感染等并发症出现,术后住院 4~6 d,监护室入住时间、呼吸机辅助通气时间及住院费用均较常规开胸手术明显降低,术后随访期间无心绞痛复发病例。 结论 胸骨下段小切口行非体外循环冠状动脉旁路移植术,创伤较小,安全可靠;而且是一种操作相对简单,容易掌握及可灵活应变的小切口微创手术,尤其适合于初学小切口冠状动脉旁路移植术术者。

    Release date:2018-06-01 07:11 Export PDF Favorites Scan
  • Transcatheter aortic valve replacement for the treatment of severe aortic valve stenosis

    Transcatheter aortic valve replacement (TAVR) is a minimally invasive approach to treat symptomatic severe aortic stenosis with surgical taboos or high risk. With the update of the guidelines, the indication of TAVR has been extended to the intermediate-risk aortic stenosis population, and even has a tendency to further expand to the low-risk population. This review highlights the research progress and new evidence of TAVR in respects of patient selection, valve and approach selection, ethnic differences, and surgical complications such as perivalvular leakage, cardiac conduction block, vascular complications, stroke, acute kidney injury, and coronary artery occlusion.

    Release date:2020-05-26 02:34 Export PDF Favorites Scan
  • Clinical Analysis of Surgical Treatment of Myocardial Bridge

    目的探讨冠状动脉心肌桥(myocardial bridge,MB)的诊断、手术适应证、手术方式及手术效果。 方法回顾性分析2010年6月至2014年12月我院13例冠状动脉心肌桥患者行外科手术治疗的临床资料,其中男9例、女4例,年龄42~68岁。单纯MB 8例,合并冠心病2例,合并瓣膜病2例,合并先天性房间隔缺损1例,单纯8例MB均在非体外循环下行心肌桥松解术,2例合并冠心病患者在非体外循环下行心肌桥松解+冠状动脉旁路移植术,其余3例均在体外循环心脏停跳下行心肌桥松解+心内畸形矫治术。 结果13例外科手术均获成功,无并发症发生,患者心绞痛症状缓解,心电图提示心肌缺血明显改善,超声心动图检查提示心功能较术前明显提高,术后随访3~48个月,1例单纯MB患者行松解术后仍有心绞痛,应用药物控制,其余术后无不适症状,冠状动脉CT显示无心肌桥。 结论对冠状动脉心肌桥行外科手术治疗,能取得较满意的近、中期效果。

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  • Clinical outcomes of right anterior mini-thoracotomy aortic valve surgery: A propensity score-matching study

    Objective To compare perioperative outcomes of minimally invasive aortic valve surgery by a right anterior minithoracotomy (RAMT) and conventional sternotomy. Methods A retrospective analysis of patients who underwent isolated aortic valve surgeries in our hospital between May 2021 and August 2023 with a minimal incision via the right anterior minithoracotomy approach (a RAMT group) or conventional incision via the full sternotomy approach (a conventional group). A propensity score-matching analysis was performed to balance preoperative data and compare perioperative data of the two groups. ResultsThere were 58 patients in the RAMT group, including 46 males and 12 females with an average age of 52.0±14.1 years; 128 patients were enrolled in the conventional group, including 87 males and 41 females with an average age of 60.0±12.4 years. After propensity-score matching, there were 51 patients in each group. The RAMT patients had a longer mean operation time, cross-clamping time and cardiopulmonary bypass time compared to the conventional group (all P<0.05). However, ICU length of stay, ventilator-assisted time and postoperative hospital stay were significantly shorter in the RAMT group (all P<0.05). Patients in the RAMT group had lower 24 hour chest drain output (P<0.05). RAMT was associated with a trend towards a lower blood transfusion rate in comparison to the sternotomy group, although this was not statistically significant (P>0.05). The occurrence of all-cause death, stroke and perioperative complications was also similar in both groups (P>0.05). Conclusion Right anterior mini-thoracotomy is associated with less trauma, faster recovery, less postoperative drainage, and shorter hospital stay than conventional approach. Right anterior mini-thoracotomy in patients undergoing isolated aortic valve surgery is a safe approach and can be performed by a wide range of surgeons.

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  • Clinical efficacy of minimally invasive coronary artery bypass grafting for multivessel coronary artery disease

    ObjectiveTo investigate the early clinical efficacy of minimally invasive coronary artery bypass grafting (MICS CABG) for multivessel coronary artery disease. MethodsThe patients who received off-pump coronary artery bypass grafting in the Central China Fuwai Hospital of Zhengzhou University from June 2021 to June 2023 were enrolled. Patients were divided into two groups according to the operative technique used, including a traditional midline sternotomy group where the full median sternotomy was performed, and a left chest small incision group where left anterior mini-thoracotomy was performed. The clinical data of the two groups were compared. ResultsA total of 143 patients were enrolled, including 70 patients in the traditional midline sternotomy group and 73 patients in the left chest small incision group. The age of the patients in the left chest small incision group and the traditional midline sternotomy group was 63.8±8.0 years and 63.0±7.8 years, respectively; the proportions of males were 69.9% and 74.3%, respectively. The differences were not statistically significant (all P>0.05). All patients in the two groups successfully completed the operation, and no patients in the left chest small incision group were converted to thoracotomy. The patients in the left chest small incision group showed less postoperative drainage within postoperative 24 hours (239.4±177.7 mL vs. 338.0±151.9 mL, P<0.001), lower perioperative blood transfusion rate [32.9% (24/73) vs. 51.4% (36/70), P=0.028], higher postoperative myoglobin level within postoperative 24 hours [366.1 (247.9, 513.0) ng/mL vs. 220.8 (147.2, 314.9) ng/mL, P<0.001], shorter intensive care unit stay [45.5 (31.5, 67.5) h vs. 68.0 (46.0, 78.5) h, P=0.001] and postoperative hospital stay (10.8±4.0 d vs. 13.1±5.3 d, P=0.028] compared to the traditional midline sternotomy group. There was no significant difference in the incidence of major adverse cardiac and cerebrovascular event between the two groups [2.7% (2/73) vs. 2.9% (2/70), P=1.000]. ConclusionCompared to the full median sternotomy, MICS CABG leads to a good clinical result with smaller trauma, faster overall recovery, and less perioperative blood transfusion.

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  • Early outcomes of domestic left ventricular assist device implantation with or without concomitant mitral valvuloplasty

    Objective To compare the early outcomes of domestic third-generation magnetically levitated left ventricular assist device (LVAD) with or without concomitant mitral valvuloplasty (MVP). Methods The clinical data of 17 end-stage heart failure patients who underwent LVAD implantation combined with preoperative moderate to severe mitral regurgitation in Fuwai Central China Cardiovascular Hospital from May 2018 to March 2023 were retrospectively analyzed. The patients were divided into a LVAD group and a LVAD+MVP group based on whether MVP was performed simultaneously, and early outcomes were compared between the two groups. Results There were 4 patients in the LVAD group, all males, aged (43.5±5.9) years, and 13 patients in the LVAD+MVP group, including 10 males and 3 females, aged (46.8±16.7) years. All the patients were successful in concomitant MVP without mitral reguragitation occurrence. Compared with the LVAD group, the LVAD+MVP group had a lower pulmonary artery systolic pressure and pulmonary artery mean pressure 72 h after operation, but the difference was not statistically different (P>0.05). Pulmonary artery systolic pressure was significantly lower 1 week after operation, as well as pulmonary artery systolic blood pressure and pulmonary artery mean pressure at 1 month after operation (P<0.01). There was no statistically significant difference in blood loss, operation time, cardiopulmonary bypass time, aortic cross-clamping time, mechanical ventilation time, or ICU stay time between the two groups (P>0.05). The differences in 1-month postoperative mortality, acute kidney injury, reoperation, gastrointestinal bleeding, and thrombosis and other complications between the two groups were not statistically significant (P>0.05). Conclusion Concomitant MVP with implantation of domestic third-generation magnetically levitated LVAD is safe and feasible, and concomitant MVP may improve postoperative hemodynamics without significantly increasing perioperative mortality and complication rates.

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