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find Author "王晶晶" 7 results
  • Value of Color Doppler Ultrasonography in Diagnosing Superficial Soft Tissue Masses

    【摘要】 目的 探讨高频彩色多普勒超声对浅表软组织肿物的诊断价值。 方法 回顾性分析2008年1-11月70例经手术、活检病理证实的浅表软组织肿物的声像图特征,包括肿物的部位、形态大小、内部回声、边界及其与周边组织的关系、长径与厚度比值(L/T)及病变周边与内部血流分布情况。 结果 超声对浅表肿块病灶的显示率为100%,良性肿瘤有脂肪瘤、表皮囊肿、滑膜囊肿、神经鞘瘤,血管瘤、异物肉芽肿等,恶性肿物包括皮肤纤维肉瘤,转移性腺癌。 结论 彩色多普勒超声对浅表肿块的检出、定位及物理性质可做出准确的诊断,综合分析肿物的边界、形态、内部回声及血流分布等特点对肿物的良恶性诊断具有重要价值。【Abstract】 Objective To evaluate the value of high-frequency color Doppler ultrasonography in diagnosing the superficial soft tissue masses. Methods The clinical data of 70 patients with superficial soft tissue masses from January to November 2008 were retrospectively analyzed. Superficial soft tissue masses was diagnosed by the surgery and biopsy. The sonographic features, including the location, morphology, size, internal echo, boundary, relationship with peripheral tissues, longitude to transverse ratio (L/T), and the vascularity, were observed. Results The results of sonographic examination showed that 100% superficial masses could be found. Benign masses included lipoma, sebaceous cysts, synovial cysts, nerve sheath tumors, haemangioma, foreign body granulomas, etc. Malignant soft tissue tumors included fibrous sarcoma and metastatic neoplasms. Conclusion Color Doppler ultrasonography can precisely diagnose the presence, localization and the physical characters of superficial soft tissue masses. It is an excellent modality to diagnose the benign or malignant masses by analyzing the boundary, configuration, internal echo and vascularity of the masses.

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
  • 改良法对脑血管造影术后卸除压迫器胶带的效果分析

    目的 分析脑血管造影患者术后两种压迫器胶带卸除方法的利弊。 方法 将2011年10月-12月收治拟行脑血管造影术的60例患者随机分成常规组和改良组(每组各30例),分别采用传统法和改良法卸除压迫器胶带,并对比两组卸除时间、皮肤损害程度及疼痛。 结果 常规组和改良组卸除胶带时间为(8.8 ± 1.1)min和(7.1 ± 1.1)min;皮肤损害程度为60.0%和13.3%;疼痛评分为(2.00 ± 1.58)和(1.06 ± 0.98)分,差异有统计学意义(P<0.05),改良法优于传统法。 结论 改良法在卸除压迫器胶带过程中,缩短了操作时间、减轻局部皮肤损害、缓解患者的疼痛,改善患者的舒适度,同时又提高医护人员的工作效率,值得推广。

    Release date:2016-09-08 09:18 Export PDF Favorites Scan
  • 早期康复护理干预对脑梗死后肢体偏瘫患者运动功能恢复的影响

    目的研究脑梗死肢体偏瘫患者运用早期康复护理干预其运动功能恢复情况。 方法对2013年1月-2014年3月36例脑梗死患者按随机数表法分为观察组和对照组,每组18例。对照组运用常规康复护理,干预组运用早期康复护理干预。比较两组干预前后患者的肌力、欧洲卒中量表评分和日常生活能力等方面的差异。 结果两组护理前后患者肌力、欧洲卒中量表评分以及日常生活能力量表评分均有显著提高(P<0.05),且干预组提高程度明显高于对照组(P<0.05)。 结论脑梗死后肢体偏瘫患者在早期康复护理干预下,其运动功能恢复佳,日常生活质量得到保障。

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  • Research on Relevance Between Mitochondrial ATP Synthase and Malignant Tumor

    Mitochondrial adenosine triphosphate (ATP) synthase is the key enzyme of mitochondrial oxidative phosphorylation reaction.The down-regulation of the mitochondrial ATP synthase is a hallmark of most human carcinomas, which is the embodiment of the bioenergetic signature of cancer in the performance of the decreased oxidative phosphorylation and increased aerobic glycolysis. Combining with the bioenergetic signature of cancer, studies showed that mitochondrial ATP synthase and multidrug resistance and adverse prognosis of tumor were closely related. Its mechanisms are related to post-transcriptional regulation of the ATP synthase,the hypermethylation of the ATP synthase gene and the inhibitor peptide of the mitochondrial ATP synthase, called ATP synthase inhibitory factor 1(IF1). In this review, we stress the biological characteristics of mitochondrial ATP synthase and the relationship between ATP synthase and multidrug resistance and prognosis of Malignant tumor, in order to find a new way for tumor therapy.

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  • Effects of short-time hyperoxia ventilation on lung tissue and pulmonary surfactant proteins C and D in rats

    ObjectiveTo investigate the effects of short-time hyperoxia ventilation on lung tissue and pulmonary surfactant proteins C and D (SP-C and SP-D) in rats.MethodsSixteen male Sprague-Dawley rats were randomly divided into two groups (n=8): hyperoxia group (FiO2=0.90), air group (FiO2=0.21). Tracheal intubations were administrated after anesthesia, and rats in two groups were exposed hyperoxia or air ventilation for 4 h. At the same time, carotid artery blood gas was analyzed after 2 h and 4 h of ventilation, then oxygenation index (OI) was calculated. Four hours later, the anterior lobe of right lung was taken to observe the pathological change and the injury level was scored. The middle lobe of right lung was prepared for making tissue homogenate, and the remaining part of the lung was used to measure the wet/dry weight (W/D) ratio. The bronchoalveolar lavage fluid (BALF) was prepared in left lung. The content of SP-C and SP-D were detected in lung tissue homogenate and BALF by ELISA.ResultsComparing with hyperoxia group, the arterial partial pressure of oxygen, lung histopathology score and lung W/D ratio in air group were significantly increased (P<0.05), but OI, the content of SP-C and SP-D in lung tissue homogenate and BALF were significantly decreased (P<0.05).ConclusionHyperoxia ventilation for 4 h in rats can cause lung injury histologically, and reduce the concentration of SP-C and SP-D apparently in the lungs.

    Release date:2021-02-08 08:11 Export PDF Favorites Scan
  • 跌倒情景教学法在神经内科本科护理学生实习带教中的应用

    目的探讨适合神经内科本科实习护理学生(护生)掌握跌倒相关知识及跌倒患者急救处理技能的带教方法。 方法以2012年4月-2013年4月实习的32名护生为研究对象,随机分为8个小组,每组4名护生在神经内科实习共6周。按照实习先后顺序,奇数纳入试验组(共4个小组),偶数纳入对照组(共4个小组)。试验组通过模拟患者跌倒急救情景进行急救训练,并结合跌倒患者预防及处理专科知识讲解;对照组则通过传统的跌倒患者预防及处理专科知识讲解进行教学。于实习结束出科前进行跌倒患者预防、急救处理理论知识及跌倒患者(模拟)处理操作进行考核,比较两组教学效果。 结果试验组出科前跌倒相关理论知识成绩及跌倒患者处理操作考核成绩均高于对照组,差异有统计学意义(P<0.05)。 结论跌倒患者情景教学法能使护生更牢固地掌握跌倒相关知识及急救技能,可激发护生的兴趣及参与热情,提升其综合能力,同时提高护理质量和患者满意度,值得推广。

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  • Efficacy and safety of escitalopram in preventing post-stroke depression: a meta-analysis

    ObjectivesTo systematically review the efficacy and safety of escitalopram in the prevention of post-stroke depression (PSD).MethodsPubMed, The Cochrane Library, CBM, WanFang Data, VIP and CNKI databases were electronically searched to collect randomized controlled trials (RCTs) on escitalopram in preventing PSD from inception to March 2019. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, meta-analysis was performed by using RevMan 5.3 software.ResultsA total of 6 RCTs involving 891 patients were included. The results of meta-analysis showed that: compared with the control group, the escitalopram group could reduce the incidence of PSD (RR=0.55, 95%CI 0.31 to 0.98, P=0.04). In addition, there was no statistical difference between escitalopram group and control group in rate of adverse events (P≥0.05).ConclusionsCurrent evidence shows that escitalopram can reduce the incidence of PSD without increasing the incidence of adverse reactions. Due to limited quality and quantity of the included studies, more high quality studies are required to verify above conclusions.

    Release date:2019-11-19 10:03 Export PDF Favorites Scan
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