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find Author "王桂林" 2 results
  • 急性胰腺炎并肝损害35例比较分析

    摘要:目的:探讨急性胰腺炎肝损害情况。方法:急性胰腺炎患者66例,对临床资料进行分析,了解肝损害的发生率、损害程度和对病程的影响。结果:伴有不同程度的肝损害35例,占53.0%,其中轻型胰腺炎(MAP)的肝损害发生率、损害程度与重型胰腺炎(SAP)相比均有显著性差异(Plt;0.05);有肝损害的胰腺炎患者,其腹痛缓解时间及住院天数均较无肝损害的胰腺炎患者明显延长。结论:急性胰腺炎肝损害发生率及损害程度与胰腺炎严重程度呈正相关,合并肝损害明显延长胰腺炎的病程。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • Analysis of condensate contamination in pipelines of severe pneumonia patients undergoing mechanical ventilation

    ObjectiveTo investigate the condensate pollution in the pipeline of severe pneumonia patients undergoing mechanical ventilation.MethodsFrom January 2017 to January 2019, 120 patients with severe pneumonia treated by mechanical ventilation in our hospital were collected continuously. The lower respiratory tract secretions were collected for bacteriological examination. At the same time, the condensed water in the ventilator exhaust pipe was collected for bacteriological examination at 4, 8, 12, 16, 20 and 24 hours after tracheal intubation and mechanical ventilation. The bacterial contamination in the condensed water at different time points was analyzed and separated from the lower respiratory tract. The consistency of bacteria in secretion and drug resistance analysis of bacterial contamination in condensate water were carried out.ResultsOf the 120 patients with severe pneumonia after mechanical ventilation, isolates were cultured in the lower respiratory tract secretions of 102 patients. One strain was cultured in 88 cases, two strains were cultured in 10 cases, and three strains were cultured in 4 cases. The isolates were mainly Gram-negative bacteria (57.5%) and Gram-positive bacteria (42.5%). The most common isolates were Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii. The contamination rate of condensate water was 5.0% at 4 hours, 37.5% at 8 hours, 60.0% at 12 hours, 76.7% at 16 hours, 95.0% at 20 hours, and 100.0% at 24 hours, respectively. The bacterial contamination rate in condensate water at different time points was statistically significant (P=0.000). The pollution rate at 4 hours was significantly lower than that at 8 hours (P=0.000). Gram-negative bacteria accounted for 57.5% and Gram-positive bacteria accounted for 42.5%. The most common isolates were Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii. The consistency of bacteria in lower respiratory tract and condensate water was 83.3% in severe pneumonia patients undergoing mechanical ventilation. The overall resistance of Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus was higher, but the resistance to imipenem/cilastatin was lower.ConclusionsThe bacterial contamination in the condensate of patients with severe pneumonia during mechanical ventilation is serious. The pollution rate is low within 4 hours. It is consistent with the bacterial contamination in lower respiratory tract and the bacterial resistance is high.

    Release date:2021-01-26 05:01 Export PDF Favorites Scan
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