目的 分析死胎死亡原因及可能的相关因素，为降低死胎发生的措施提供依据。 方法 对2007年1月－2011年12月住院分娩的609例死胎（≥28周） 的病例资料进行回顾性分析,包括对产检次数差异、死胎性别、死胎孕周分布、母亲年龄差别、母亲文化程度等进行统计分析。 结果 ① 死胎的原因依次为：胎儿因素（41.2%），母体因素（24.1%），胎盘因素（21.7%）及不明原因（13.0%）；其中胎儿畸形、重度子痫前期及胎盘早剥为主要原因；② 母亲的文化程度低、未建卡或未正规产检者死胎发生的几率高于正规产检者，差异有统计学意义（P＜0.05）。 结论 加强围产保健，早期筛查胎儿畸形、防治妊娠期并发症及合并症等都有助于降低死胎的发生率。
Objective To analyze the effectiveness of conservative medical treatments for ectopic pregnancy (EP): methotrexate (MTX) + mifepristone + Ectopic Pregnancy II decoction (EP-II) vs. methotrexate + mifepristone. Methods A total of 95 patients with EP in Shenzhen Shajing Affiliated Hospital of Guangzhou Medical University from January 2009 to January 2011 were randomly divided into two groups: 45 patients in the experimental group were treated with MTX, mifepristone and EP II decoction, while the other 50 patients in the control group were treated with MTX and mifepristone. The effectiveness of the two groups was analyzed with SPSS 13.0 software. Results There were significant differences in the time of serum β-HCG return to normal (16.13±8.13 ds vs. 22.05±7.15 ds, Plt;0.05), time of EP mass absorption (30.46±7.56 ds vs. 39.99±18.26 ds, Plt;0.05) and tubal patency rate (80% vs. 75%, Plt;0.05) between the two groups. But there were no significant differences in effective rate (95.56%, 43/45 vs. 94%, 47/50, χ2=0.0809, Pgt;0.05) and side effects. Conclusion The combination of methotrexate, mifepristone and EP II decoction for ectopic pregnancy is more effective than mifepristone and methotrexate in coordinately killing the embryo, shortening the time of serum β-HCG return to normal and the time of EP mass absorption, and improving the function of oviducts.