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find Author "王连才" 2 results
  • 开放前热血加甘露醇灌注在危重心脏瓣膜疾病患者术中的应用

    目的 为了较好地进行心肌保护,研究主动脉开放前热血加甘露醇灌注在危重心脏瓣膜病患者体外循环术中的应用。 方法 选取我院1998年6月~1999年6月间80例心脏瓣膜病患者,随机分为实验组和对照组,每组各40例,常规行二尖瓣和/或主动脉瓣置换术。两组均采用中度低温含血心肌保护,实验组于主动脉开放前给予热血加甘露醇灌注。比较两组患者体外循环术后心功能恢复情况。 结果 在自动复跳率、主动脉开放后体外循环时间、24小时内心排血指数恢复速度、肌酸激酶下降幅度等指标实验组明显优于对照组(P<0.05),在术后呼吸机支持时间、ICU滞留时间、正性肌力药物使用率、手术死亡率等方面两组无明显差异(P>0.05)。 结论 主动脉开放前热血加甘露醇灌注能明显减轻再灌注损伤,加快术后早期心功能恢复。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • Surgical Treatment for Patients with Stanford Type A Aortic Dissection

    ObjectiveTo summarize our clinical experience of surgical treatment for 51 patients with Stanford type A aortic dissection (AD). MethodsClinical data of 51 patients with Stanford type A AD who received surgical treatment in Shanghai Yuanda Heart Hospital between February 2009 and January 2013 were retrospectively analyzed. There were 29 males and 22 females with their age of 35-63 (47.2±11.1)years. The diagnosis of all the patients was confirmed by enhanced CT scan and Doppler echocardiography. Surgical procedures included Bentall procedure and Sun's procedure in 29 patients, Bentall procedure, mitral valve replacement and Sun's procedure in 2 patients, ascending aorta replacement and Sun's procedure in 17 patients, valsalva sinus plasty, ascending aorta replacement and Sun's procedure in 2 patients, ascending aorta replacement (stage 1), Sun's procedure (stage 2)and endovascular exclusion of the thoracic aorta (stage 3)in 1 patient. ResultsMean operation time was 320.6±77.3 minutes, cardiopulmonary bypass time was 190.4±63.4 minutes, aortic cross-clamp time was 123.2±45.1 minutes, duration of circulatory arrest with hypothermia was 28.2±11.1 minutes, and mean length of hospital stay was 13.4±4.2 days. Two patients (3.9%)died perioperatively including 1 patient with intraoperative bleeding and another patient with delayed bleeding after operation. Postoperative complications included bleeding, paraplegia, perivalvular leak and sternal dehiscence in 1 patient respectively, and endoleak in 2 patients. Forty-nine patients were followed up for 3-48 (25.3±10.5)months and no late death occurred. ConclusionSurgical treatment is effective for patients with Stanford type A AD.

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