目的:探讨输卵管性不孕妇女生存质量及其影响因素,并为输卵管性不孕症治疗决策的选择提供相应的依据。方法:采用生存质量测评量表SF-36对80名输卵管性不孕妇女及80名已生育或妊娠的健康妇女进行了同期的横断面调查与比较。结果:输卵管性不孕妇女的生存质量较正常健康妇女人群低,除了生理功能及躯体疼痛外,输卵管性不孕妇女有关社会功能、生理问题对功能的限制、心理问题对功能的限制、心理健康、活力、健康的总体评价、健康变化程度等七个方面的主观满意度均较对照组低,差异有显著意义(Plt;0.05)。患者的年龄、文化程度及居住环境对其生存质量有影响。结论:在治疗不孕症时,不应仅针对其病因治疗,而且要重视心理和社会因素的作用,加强心理治疗,重视健康教育,针对性地改善患者在精神、社会、心理等方面的主观体验,以促进不孕症妇女生存质量的提高。
目的:观察A型肉毒毒素(BTXA)对面肌痉挛(HFS)患者痉挛程度的改善和生存质量的影响。方法: 对68例HFS患者进行局部注射BTXA,治疗前及治疗后1个月分别对患者的痉挛程度进行判定和使用世界卫生组织生存质量评定量表简表(WHOQOL-BREF)评价生存质量。 结果: 97.04%的HFS患者在BXTA治疗后1个月痉挛明显改善缓解,而且患者在WHOQOL-BREF的生理领域、心理领域、社会关系领域、总的健康状况和总的生存质量的评分均明显高于治疗前,差异有统计学意义(Plt;0.01)。 结论: 局部注射BTXA可迅速缓解或消除HFS患者肌肉痉挛,提高患者的生存质量。
摘要:目的:观察复方苦参注射液配合化疗治疗晚期胃癌的临床疗效。方法:将60例晚期胃癌患者分为两组,两组均采用FOLFOX方案化疗,21天为1个周期;2个周期评价效疗。治疗组30例加用复方苦参注射液治疗,14天为1疗程,2个疗程评价疗效。观察近期疗效及临床证候变化、生存质量及毒副反应变化。结果:两组近期疗效比较,治疗组与对照组总缓解率分别为433%和400%(P>005);两组临床证候变化比较,治疗组与对照组总改善率分别为800%和600%(P<005);两组生存质量变化比较,治疗组与对照组提高稳定率分别为867%和567%(P<005);中位生存期分别为8个月和5个月;两组毒副反应比较,治疗组毒副反应明显低于对照组(P<005)。结论:复方苦参注射液配合化疗治疗晚期胃癌具有一定抗肿瘤作用,能缓解疼痛症状及临床症状,减轻化疗毒副反应,提高生活质量,延长生存期。Abstract: Objective: To study the effect of combination FuFang Ku Shen Zhusheye and chemotherapy for treatment of advanced gastric cancer. Methods: Sixty patientswith advanced gastric cancer were divided into two groups, all used with FOLFOXregimen, 21 days a cycle; twocycle assessment of treatment effect. The treatment group were treated with the FuFang Ku Shen Zhusheye plus treatment, a course of treatment for 14 days, the effect were evaluated after two courses. The clinical symptoms and living quality, toxicity were dynamically observed. Results: Both shortterm effect of comparison, the overall response rates of the treatment group and the control group were 433% and 400% (P>005); The rates of clinical symptoms of the treatment group and the controlgroup were 800% and 600% respectively (P<005); the rates of increasing of living quality were respectively 867% and 567% (P<005); the median survival time was 8 months and 5 months; the toxicity of the treatment group was significantly lower than that of the control group (P <005).Conclusion: Treating advanced gastric cancer by use of FuFang Ku Shen Zhusheye combination with chemotherapy is helpful to reducing the pain symptoms, promoting the clinical symptoms, reducing the chemotherapy side effects, improving quality of life and prolonging the survival time.