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find Keyword "病毒性脑炎" 6 results
  • Efficacy and Safety of Naloxone for Viral Encephalitis: A Systematic Review

    目的 系统评价纳洛酮治疗病毒性脑炎的疗效与安全性。 方法 计算机检索Medline、Cochrane图书馆、EMbase、CBM、CNKI、万方从建库至2012年2月收录的相关中英文文献,收集所有关于在抗病毒、肾上腺皮质激素以及脱水、止惊、降温等综合治疗的基础上,辅助应用纳洛酮治疗病毒性脑炎对照试验。根据纳入与排除标准筛选文献、评价质量、提取资料,采用RevMan 5.1软件进行Meta分析。 结果 共纳入5个对照试验,包括279例病毒性脑炎患者。Meta分析结果显示:纳洛酮的应用对13岁以上病毒性脑炎患者的总有效率[RR=1.15,95%(0.94,1.42),P=0.18]及死亡率[RR=0.45,95%(0.17,1.16),P=0.10]并无影响,但可以缩短退热时间[WMD=−0.85,95%(−1.74,0.03),P=0.06]、头痛消失时间[WMD=−0.40,95%(−0.55,0.25),P<0.000 01]、抽搐停止时间[WMD=−0.87,95%(−1.09,−0.66),P<0.000 01]、意识恢复时间[WMD=−1.10,95%(−2.05,−0.15),P=0.02]、脑膜刺激征消失时间[WMD=−0.15,95%(−0.73,0.29),P<0.000 01]、呼衰纠正时间[WMD=−1.22,95%(−2.11,−0.33),P=0.007]及病程[WMD=−1.38,95%(−2.65,−0.11),P=0.03]。 结论 现有证据表明,纳洛酮不能提高病毒性脑炎的疗效,但对改善症状有一定帮助。受本系统评价纳入研究数量和质量的限制,上述结论尚需更多高质量的随机对照试验验证。

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  • 重症病毒性脑炎伴低颅压综合征护理一例

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • 以精神症状为首发的病毒性脑炎合并甲状腺功能亢进患者的护理体会

    目的探讨以精神症状为首发的病毒性脑炎合并甲状腺功能亢进(甲亢)患者的护理要点。 方法通过对2012 年8 月收治的1 例合并精神症状的病毒性脑炎合并甲亢患者的治疗、护理等临床资料的分析,总结病毒性脑炎与甲亢共存状况下如何进行针对性的护理。 结果患者病情得到及时控制,症状改善明显,治疗痊愈后出院。 结论以精神症状为首发的病毒性脑炎合并甲亢患者护理难度较大,需要医护人员提高对基础疾病及其症状的认识,给予及时、准确的判断和临床专科护理,减少并发症的产生,缩短住院时间,提高患者生活质量。

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  • 病毒性脑炎合并急性视网膜坏死一例

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  • Efficacy of immunoglobulin for treatment of clinically diagnosed viral encephalitis in China: a meta-analysis

    ObjectiveTo systematically review the efficacy of immunoglobulin for treatment of clinical diagnosed viral encephalitis in China.MethodsCNKI, VIP, WanFang Data, PubMed, ScienceDirect, The Cochrane Library and EMbase databases were electronically searched to collect randomized controlled trials (RCTs) of immunoglobulin for treatment of clinical diagnosed viral encephalitis in China from inception to January 2021. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Meta-analysis was then performed by using RevMan 5.4 software.ResultsA total of 57 RCTs involving 4 431 patients were included. The results of meta-analysis showed that in both children and adults of clinically diagnosed viral encephalitis, the combination of immunoglobulin could reduce the mean recovery time of fever, unconsciousness, convulsion, emesis, average hospitalization time, and non-effective rate. Moreover, there was no difference in the incidence of adverse effects between the two groups.ConclusionsCurrent evidence shows that immunoglobulin is superior to conventional therapies both in adults and children patients of clinically diagnosed viral encephalitis. Due to the limited quality and quantity of the included studies, more high-quality studies are needed to verify the above conclusions.

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  • 免疫功能正常青少年人类疱疹病毒-7 型相关脑炎一例

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