目的 观察盐酸氨基葡萄糖胶囊在髌骨骨折内固定术后促进膝关节功能恢复及缓解患者疼痛等临床症状方面的疗效。 方法 选取2009年1月－2012年1月收治入院的髌骨横行骨折患者52例，采用随机数字表法将患者随机分为试验组以及对照组，其中试验组患者26例，对照组患者26例，两组患者的性别、年龄、病情等临床资料，差异无统计学意义（P＞0.05）,具有可比性。其中，对照组仅在术后进行康复锻炼，试验组术后给予盐酸氨基葡萄糖内服，连续服用3个月。根据术后2、6周，6、12个月随访记录中的膝关节功能评分（采用KSS评分）分析疗效。 结果 对照组和试验组在骨折愈合程度比较差异无统计学意义（P＞0.05），试验组的膝关节功能评分在早期与对照组差异无统计学意义（P＞0.05），但在第12个月的随访评分中，试验组患者膝关节功能评分较对照组差异具有统计学意义（P＜0.05）。 结论 盐酸氨基葡萄糖胶囊有利于髌骨骨折术后患者的功能恢复及疼痛症状的缓解。
ObjectiveTo observe the therapeutic effect of electro-acupuncture combined with oral glucosamine hydrochloride capsules in the treatment of knee osteoarthritis, and compare it with the curative effect of the two methods separately. MethodsA total of 168 patients with knee osteoarthritis treated from March 2006 to December 2012 were randomly divided into 3 groups. Electro-acupuncture combined with oral glucosamine hydrochloride capsules were given to the 58 patients in the treatment group, single acupuncture treatment was given to the 57 patients in control group A, and simple oral glucosamine hydrochloride capsules were given to the 53 patients in control group B. The treatment lasted for 6 weeks. Assessment of knee osteoarthritis by Lequesne international standard index number and the total efficiency was carried out before treatment and 3 weeks, 6 weeks and 6 months after treatment, respectively. ResultsThe total effective rate of the treatment group was 91.38%, of control group A was 68.42%, and of control group B was 79.25%. There was a significant difference between the treatment group and control group A, and between the treatment group and control group B (P<0.05). No blood, liver or kidney damage or gastrointestinal adverse reaction occurred among patients in all the three groups. ConclusionThe efficacy of electro-acupuncture plus oral glucosamine hydrochloride capsules is better than simple acupuncture and simple oral glucosamine hydrochloride capsules treatment.