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find Keyword "眼疾病" 51 results
  • Research progress of microglia in hereditary retinal degeneration

    The human hereditary retinal degeneration is one of the main cause of irreversible blindness in the world. the mechanisms leading to retinal photoreceptor degeneration are not entirely clear. However, microglia acting as innate immune monitors are found to be activated early in retinal degeneration in many retinitis pigmentosa animal models. These activated microglia are involved in phagocyte rod cell fragments of degenerated retina, and also produce high levels of cytotoxic substances such as pro-inflammatory cytokines and chemokines, which aggravate the death of adjacent healthy photoreceptor cells. It suggests that microglia activation plays an important role in photoreceptor degeneration. At the same time, a series of studies have confirmed that some drugs can prevent or reduce neuronal death and slow the occurrence and progression of retinal degeneration by interfering with abnormal activation of microglia. It is expected to be a new choice for the treatment of hereditary retinal degeneration.

    Release date:2022-09-14 01:19 Export PDF Favorites Scan
  • 核因子-κB与眼底病研究进展

    核因子-kappa;B(nuclear factor-kappa B, NF-kappa;B)是一个多功能核转录因子,具有广泛的生物学活性,直接参与机体对炎症和免疫反应的调控,在细胞凋亡中起到一种稳定作用,并参与新生血管的形成。NF-kappa;B在炎症性视网膜疾病、视网膜光损伤、视网膜新生血管形成等的病理过程中起关键作用。对NF-kappa;B的基础研究极大地推动了对炎症、细胞凋亡及新生血管形成等相关疾病的认识,为相关疾病的发病机制和治疗研究开辟了新的途径。 (中华眼底病杂志, 2002, 18: 320-322)

    Release date:2016-09-02 06:01 Export PDF Favorites Scan
  • 一氧化氮与眼底病相关研究的新进展

    许多研究表明一氧化氮(NO)同眼底循环血管性眼病、皮质盲、葡萄膜炎、青光眼等的发病有密切联系,并对这些眼病的发病机制提出了新的认识,也为它们的治疗提供了新的思路。 (中华眼底病杂志,1996,12:59-61)

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • Features of computer-assistant three-dimensional ultrasound diagnosis in ocular fundus diseases

    Objective To detect the value of three-dimensional (3D) ultrasound diagnosis in common ocular fundus diseases. Methods Two-dimensional (2D) images of 38 patients with common ocular fundus diseases were three-dimensionally reconstructed via 3D ultrasound workstation. The 3D images reflecting the ocular diseases were analyzed. Result In 38 patients with common ocular fundus diseases, there was vitreous hemorrhage in 16 patients, retinal detachment in 12, choroidal detachment in 5, and intraocular space occupying lesion in 5. Compared with the 2D images, 3D reconstructed images reflect the lesions more intuitionistically, displayed the relationship between the lesions and the peripheral tissues more clearly, and revealed the blood flow more specifically. During a scanning examination, 3D reconstructed technology provided the diagnostic information of section of X, Y and Z axises simultaneously which shortened the time of examination; the condition of any point of lesions and the relation between the lesion and the peripheral tissues could be gotten by the tools like cut and chop provided by 3D imaging software itself, which avoided detecting the same lesion with different angles and lays and proved the diagnostic efficacy. Conclusions 3D ultrasound diagnosis is better than 2D in diagnosis of vitreous, retina, choroid, and intraocular space occupying lesion. 3D ultrasound diagnosis is a complementarity for the 2D one, and the Z axis changes the former observational angles which may provide the new way of precise diagnosis. (Chin J Ocul Fundus Dis, 2005, 21: 381-383)

    Release date:2016-09-02 05:52 Export PDF Favorites Scan
  • 永存性原始玻璃体增殖症一例

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • 《中华眼底病杂志》1996~2000年所载文献的计量分析

    Release date:2016-09-02 05:58 Export PDF Favorites Scan
  • 登革热相关眼病

    登革热是由登革病毒引起、经伊蚊叮咬传播的一种急性传染病。登革病毒引起的补体系统激活、血小板及凝血功能障碍, 可导致血管通透性增高、出血为特征的登革热相关眼病。其中, 以结膜下出血、葡萄膜炎、黄斑水肿较常见; 其他还包括视神经病变、玻璃体炎、视网膜静脉阻塞、视网膜小动脉分支阻塞等。症状主要为视物模糊、视野区中心暗点、眼部疼痛。在患者流行病学史、临床表现及实验室检查确诊登革热基础上, 结合其临床表现和眼部检查, 可诊断为登革热相关眼病。治疗主要在于治疗其原发病; 相关眼病多为自限性疾病不需采取特殊治疗措施。对持续存在并且造成视力严重危害的相关眼病, 糖皮质激素治疗是常用治疗手段。其具体给药方式取决于相关眼病的严重程度。

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  • 无脉络膜症一例

    Release date:2016-09-02 05:52 Export PDF Favorites Scan
  • 彩色多普勒能量图在眼部疾病的诊断应用

    Release date:2016-09-02 06:08 Export PDF Favorites Scan
  • 脉络膜缺损伴缺损区巨大囊肿一例

    Release date:2016-09-02 06:05 Export PDF Favorites Scan
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