Objective To systematically review the effectiveness and safety of flexible ureteroscope lithtripsy (fURL) and percutaneous nephrolithotomy (PCNL) in treating renal calculus. Methods Such databases as MEDLINE, EMbase, The Cochrane Library, CNKI, CBM, VIP, and WanFang Data from January, 1990 to August, 2012 were searched to comprehensively collect the clinical trials that compared fURL and PCNL in treating renal calculus. Two reviewers independently screened studies according to exclusion and inclusion criteria, extracted data, and assessed the methodological quality. Then, meta-analysis was performed using RevMan 5.1 software. Results Eight non-randomized controlled trials involving 536 patients were included. The results of meta-analysis showed that, PCNL was better than fURL in stone clearance (OR=0.26, 95%CI 0.15 to 0.46), but fURL was better than PCNL in postoperative pyrexia (OR=0.1, 95%CI 0.42 to 3.35), the incidence of blood transfusion (OR=0.17, 95%CI 0.03 to 1.00), and the duration of hospitalization (P=0.45, I2=0%). Conclusion Current evidence has proved that PCNL is better than fURL in decreasing stone clearance, fURL is better than PCNL in complication, the duration of hospitalization, and medical costs.
Objective To discuss the prevalence of melamine-induced urolithiasis in infants and its development and to formulate more effective diagnosis and treatment. Methods A total of 402 cases of melamine-induced infantile urolithiasis were retrospectively analyzed with basic information, blood, urine, urinary B-mode ultrasonic diagnosis, treatment options and prognosis for infant urolithiasis. Results A total of 402 cases of infants had an excessive melamine milk feeding history, in which there were 9 self-discharged cases. The largest calculus diameter was 4 mm × 5 mm × 6 mm. The smallest calculus diameter was 0.5 mm × 0.5 mm × 1 mm. The average calculus diameter was 1 mm × 2 mm × 2 mm. There were 30 cases of abnormal serum creatinine, 27 of abnormal urea, 2 of abnormal uric acid, and urine occult blood positive for 167 cases. There were 395 cases which were administrated medical treatment; 7 cases were administrated surgical treatment; 6 cases had obstructive renal failure. Conclusion Infants whose age is more than six months but less than 12 months with a history of exposure to melamine have the larger risk of urolithiasis. B-mode ultrasonic diagnosis is practically significant on early screening urolithiasis. It is effective to perform surgical treatment for obstructive renal failure caused by calculus.
Objective To investigate the incidence of urolithiasis in infants aged 0-3 years old fed by milk powder tainted with melamine in the middle area of the Anhui province, as well as its relationship to gender, age, milk powder consumption and drinking water. Methods Questionnaires were distributed to 1079 infants who were screened for urolithiasis by ultrasound examination from September 25, 2008 to October 17, 2008. Data was collected by Epidata and analyzed by SPSS 13.0 software. Results A total of 646 (59.87%) male infants and 433 (40.13%) female infants underwent ultrasound examination in Anhui Provincial Hospital. Of these, 86 infants were diagnosed with urolithiasis with an incidence of 7.97%, including 62 males (72.09%) and 24 females (27.91%). The mean age of those infants with urolithiasis was 1.85±0.77, and all of calculus was located in kidney. The relationship between the incidence of urolithiasis and gender, age, drinking water, feeding bottle sanitation, birth status, as well as the amount of milk powder intake was assessed by using the Pearson Chi-square test. Results showed that significant differences were noted in the incidence of urolithiasis among infants of different genders or with different drinking water sources (Plt;0.05). The result of multiple logistic regression analyses indicated that gender was related to the incidence of urolithiasis (Plt;0.05). The incidence of urolithiasis in female infants was only 58.7% of that in male infants (OR 0.587, 95%CI 0.359 to 0.959). Conclusion The incidence of urolithiasis in infants aged 0-3 years of old in the middle area of Anhui province is relatively high and has anatomical specificity. Further data during the follow-up of these cases should be collected.
【摘要】 目的 探讨后腹腔镜输尿管切开取石的临床疗效和体会。 方法 对2005年1月-2009年12月收治的45例输尿管结石患者经后腹腔镜切开取石的临床资料进行回顾性分析。其中男27例，女18例；左侧20例，右侧25例；结石直径6～14 mm。 结果 45例输尿管结石患者经后腹腔镜切开取石顺利，手术时间55～170 min，平均（95.3±19.1） min，出血量20～60 mL，平均45.3 mL，住院时间4～8 d，平均5.7 d。术后无感染，随访12个月，未见复发。 结论 经后腹腔镜输尿管切开取石安全，有效，创伤小，术后恢复快。【Abstract】 Objective To investigate the therapeutic effect of retroperitoneal laparoscopic ureterolithotomy. Methods From January 2005 to December 2009, the clinical data of 45 patients with ureteral stone undergoing retroperitoneal laparoscopic ureterolithotomy were retrospectively analyzed. Of the 45 patients, 27 were males and 18 were females, who age ranged from 31 to 59 years with a mean of (41.8±4.6) years. Twenty patients had left ureteral stone and 25 had right ureteral stone. The diameter of stone ranged from 6 to 14 mm. Results All the operations were successfully performed. The operative duration was 55-170 minutes with a mean of (95.3±19.1) minutes. The operative blood loss was 20-60 mL with a mean of (45.3±12.4) mL. The postoperative hospitalization was 4-8 days with a mean of 5.7 days. No postoperative infection was found. Conclusion Retroperitoneal laparoscopic ureterolithotomy is safe, effective, micro-invasive and easy to recovery for ureteral stone.
【摘要】 目的 总结腹腔镜胆囊切除术（laparoscopic cholecystectomy，LC）治疗结石嵌顿性急性胆囊炎的疗效。 方法 2001年8月-2009年11月，采用LC治疗187例结石嵌顿性急性胆囊炎。 结果 179例顺利完成 L C手术；8例术中改为开腹手术。其中3例术后发生胆瘘，均经乳胶管引流胆汁，7～14 d后拔管；其余患者均痊愈出院。 结论 LC治疗结石嵌顿性急性胆囊炎安全可行，但应遵循个体化原则，熟练镜下操作技巧及正确处理方法是获得满意疗效关键。
目的:探讨肝胆管结石合并胆管癌的临床表现特征和诊治经验。方法:分析了自2001年1月到2009年8月我院收治的30例肝胆管结石合并胆管癌患者的临床资料。结果:肝胆管结石合并胆管癌术前确诊10例,术中病理检查确诊14例,术后病理检查发现6例。左肝胆管癌16例,占533%,右肝胆管癌7例占233%,肝门部胆管癌5例占167%,其余2例为左右肝都有。肿瘤根治性切除术17例(567%),姑息性手术9例(30%),单纯活检4例(133%)。在30例随访资料中,根治性切除术者平均存活时间26个月。存活1年以上10例,2年以上5例,3年以上2例;姑息治疗者术后平均生存9个月;其余的≤4个月。结论:胆石症状易反复发作,胆道病史较长大于10年且术前CA199gt;2500 ng/mL的患者应高度怀疑合并有胆管癌。
目的:探讨腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)治疗急性结石嵌顿性胆囊炎的可行性。方法:总结分析2007年10月至2009年6月36例急性结石嵌顿性胆囊炎行腹腔镜胆囊切除术的经验体会,包括手术适应证及手术技巧等。结果:35例(972％)成功完成腹腔镜胆囊切除术,1例(28％)中转开腹,无胆管、肠管损伤,无术后出血及围手术期(术后30天)死亡等并发症,均获治愈。术后随访4月～23月无手术并发症。结论:在术者熟练的操作技巧,合理选择中转开腹时机的前提下,急性结石嵌顿性胆囊炎行腹腔镜胆囊切除术安全、可行。