west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "维生素" 73 results
  • Effects of Vitamin D Supplement on Blood Pressure: A Systematic Review

    Objective To systematically review the impact of vitamin D supplement on blood pressure, so as to provide a basis for clinical treatment. Methods Such databases as The Cochrane Library (Issue 8, 2011), MEDLINE (1996 to August 2011), EMbase (1974 to August 2011), CBM (1989 to 2011), CNKI (1997 to August 2011) and VIP (1989 to 2011) were searched to collect the randomized controlled trials (RCTs) about the impact of vitamin D supplement on blood pressure. Two reviewers independently screened the literature according to the inclusion criteria, extracted the data and assessed the quality. Then the meta-analysis was performed using RevMan 5.0 software. Results A total of 8 studies involving 907 participants were included. The methodological quality based on the improved Jadad scales displayed that, 7 studies scored 4 to 7 and only 1 study scored less than 4. The results of meta-analysis showed that compared with the placebo groups, vitamin D supplement had no significant difference in both systolic and diastolic blood pressure. Conclusion Based on current research evidences, compared with placebo, vitamin D supplement has no marked impact on either systolic or diastolic blood pressure. Due to the lack of studies, this conclusion still needs to be proved by conducting more well designed, large sample, and multicenter RCTs.

    Release date: Export PDF Favorites Scan
  • Effect of B Vitamins Supplementation on Cardiovascular and Cerebrovascular Disease by Lowering Plasma Homocysteine Concentration: A Meta-analysis

    Objective To assess the effect of B vitamins supplementation on cardiovascular and cerebrovascular diseases, and also to evaluate the relationship between homocysteine and risk of cardiovascular and cerebrovascular diseases. Methods Using the words ‘homocysteine’, ‘cardiovascular disease’, ‘cerebrovascular disease’, ‘B vitamins’, and ‘randomized controlled trial’, we searched PubMed, Ovid, and Springer. We also hand searched relevant journals and conference proceedings. Randomized controlled trials published between 1998 and July 2008 which evaluated the effect of B vitamins supplementation on vascular diseases were collected. Two reviewers independently screened trials, extracted data, and evaluated the quality of included trials. The Cochrane Collaboration’s RevMan 4.2 software was used for statistical analysis. Results Sixteen trials involving 27,043 patients with vascular disease were included. Results of meta-analyses showed that no significant differences were identified between the B vitamins group and the control group for each of the four endpoints, including the risk of cardiovascular events (RR 0.98, 95%CI 0.94 to 1.03), the risk of coronary heart disease (RR 0.99, 95%CI 0.92 to 1.07), the risk of stroke (RR 0.90, 95%CI 0.80 to 1.02), and the total mortality (RR 0.98, 95%CI 0.92 to 1.05). Sensitivity analyses conducted by a random effect model or with the exclusion of low-quality trials did not change the overall results. Conclusion  The trials currently available cannot confirm the causal relationship between homocysteine and risk of cardiovascular and cerebrovascular diseases. More evidence from large-scale randomized controlled trials is needed to confirm this. There is not sufficient evidence to show that B vitamins supplementation can lower the risk of cardiovascular and cerebrovascular diseases. B vitamins supplementation should not be recommended for the secondary prevention of such diseases.

    Release date:2016-08-25 03:36 Export PDF Favorites Scan
  • 黄芪治疗病毒性心肌炎40例疗效观察

    摘要:目的:观察黄芪注射液治疗病毒性心肌炎(VMC)的临床疗效。方法:选择心肌炎患者40例,随机为两组:对照组(20例)常规给予能量合剂、维生素C、聚肌胞及抗心律失常药物等对症治疗。治疗组(20例)在常规治疗的基础上加用黄芪注射液各40 ml,加入10葡萄糖液250ml滴注15 d治疗。 结果:治疗组与对照组相比.总有效率分别为95%和75%,两组相差显著(Plt;0.01),且未见不良反应。 结论:常规治疗基础上加用黄芪治疗病毒性心肌炎可缩短VMC病程,促进痊愈。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • Clinical Analysis of Superior Mesenteric Artery Syndrome Complicated with Wernicke Encephalopathy

    ObjectiveTo explore the pathogenesis, diagnosis and treatment of superior mesenteric artery syndrome (SMAS) complicated with Wernicke encephalopathy (WE). MethodsThe clinical data of 11 cases of SMAS patients complicated with WE were retrospectively analyzed. ResultsOf 9 SMAS patients complicated with WE, 8 patients were gradually awake and the time of consciousness recovery was from 7 d to 9 weeks (mean 5.2 weeks). Another 1 patient died of multiple organ failure attributed to severe condition. The symptoms of ophthalmopegia and ataxia in the rest 2 patients improved. All of symptoms such as ataxia, nystagmus, tinnitus, nausea, and sweating gradually disappeared. The nystagmus disappeared from 3 h to 4 d (mean 2.3 d) in five patients and the ataxia disappeared from 3 d to 12 weeks (mean 7.0 weeks) in 4 patients. The tinnitus, nausea, and sweating in 6 patients disappeared within 1 week. ConclusionImproving the understanding of SMAS complicated with WE is important during clinical practice and early diagnosis and intervention is the key point for a good prognosis.

    Release date:2016-09-08 10:46 Export PDF Favorites Scan
  • THE PROTECTING EFFECT OF VITAMIN E ON LIVER FUNCTION FOLLOWING ACUTE CHOLANGITIS

    To study the lipid peroxidation injury and the protecting effect of vitamin E emulsion on liver function following acute cholangitis. During the operation and 24 hours after operation, vitamin E emulsion or placebo emulsion was infused via mesenteric vein in rats suffering acute cholangitis. The contents of malondialdehyde (MDA), superoxide dismutase (SOD) and adenosine triphosphate (ATP) in the liver tissue and serum were measured at 48hrs after operation. Results: As compared with the placebo emulsion group, MDA and mGOT contents in the liver tissue and serum decreased significantly, but SOD activity increased dramatically in the VE emulsion group. ATP content in the infected lobe was much higher than those in the placebo emulsion group. Conclusion: Intravenous infusion of large dose of vitamin E emulsion may reduce the lipid peroxidation reaction in acute cholangitis, and have protecting effect.

    Release date:2016-08-29 09:18 Export PDF Favorites Scan
  • THE STUDY ON THE FAT SOLUBLE VITAMINS ABSORPTIONS AFTER OPERATIVE TREATMENT OF THE CONGENITAL BILIARY DILATATION

    In order to observe the absorption of the fat solube vitamine afer operative treatment of the congenital biliary dilation(CBD),the plasma fat soluble vitamin A,D and E were determined in 57 cases of CBD at the postoperative stage and 51 cases of normal children as control.The normal values of vitamin A,D and E was 576.25±170.93ng/ml,13.21±2.20ng/ml and 7.34±1.96ng/ml respectively in control group versus 501.59±120.64ng/ml, 11.66±1.81ng/ml and 6.16±1.18ng/ml respectively in the postoperative group of CBD.The differences were significant for a long period of about 10 years,and gradually disappear after that to approach or near the normal level.Therefor,the radical operation of CBD may affect the absorption of the fat soluble vitamins.

    Release date: Export PDF Favorites Scan
  • Effects of vitamin C on the DNA of type II alveolar epithelial cells of the rats fed with low selenium and high cadmium fodder

    Objective To elucidate the etiology of DNA impairment of type Ⅱ alveolar epithelial cells(AT-II) of the rats fed with low selenium and high cadmium fodder,and the effect of Vitamin C.Methods With single cell gel electrophoresis technique,we observed the joint action of selenium,cadmium and vitamin C on DNA damage in AT-II cells of the eight groups of rats fed separately with:normal (2 groups),high Cd,high Cd+high VC,low Se+high Cd,low Se+high Cd+high VC,high Se+high Cd and high Se+high Cd+high VC fodder for 14 weeks.Results Compared with the control,there was no DNA changes have been observed in the high Se+high Cd+high VC group.However,in the high Se+high Cd group and high Cd+high VC group,DNA damage of AT-II cells can be detected clearly;in the low Se+high Cd+high VC group and high Cd group,the degree of the DNA damage is more serious than the above two groups;in the low Se+high Cd group,the extent of the DNA damage was the most serious on all of the groups be studied.Conclusion It is suggested that Se deficiency and simultaneously Cd overabundance may damaged DNA of AT-II cells of the rats significantly,however,Vitamin C may protect AT-II against the injury effectively.

    Release date:2016-09-14 11:53 Export PDF Favorites Scan
  • 慢性呼吸衰竭COPD 患者血清维生素E 及血管性血友病因子水平测定及意义

    目的 探讨慢性呼吸衰竭COPD 患者血清维生素E( VE) 和血管性血友病因子( vWF)水平和临床意义。方法 荧光分光光度计测定50 例慢性呼吸衰竭COPD 患者的血清VE 水平, 免疫比浊法测定其血清vWF水平, 与20 例正常志愿者比较。结果 与正常对照组比较, 慢性呼吸衰竭的COPD 患者血清VE 水平显著降低[ ( 31. 79 ±11. 17) μmol /L 比( 68. 36 ±21. 03) μmol /L, P lt;0. 05] ,而血清vWF 水平明显增高[ ( 81. 79 ±21. 06) U/L比( 41. 98 ±11. 64) U/L, P lt;0. 05] 。结论 慢性呼吸衰竭COPD 患者血氧分压降低, 机体缺氧导致氧自由基清除能力降低, 对血管内皮细胞造成潜在损伤。

    Release date:2016-08-30 11:53 Export PDF Favorites Scan
  • 孕妇补充维生素A 对子女肺功能的影响(Maternal vitamin A supplementation and lung function in offspring)

    孕妇补充维生素A 对子女肺功能的影响(Maternal vitamin A supplementation and lung function in offspring) 【摘要翻译】 背景: 维生素A 在肺早期发育和肺泡形成中发挥重要的调节作用。孕妇维生素A 的水平可能是影响胚胎肺泡形成的一个重要因素, 孕妇维生素A 缺乏对其子女肺健康具有不利影响。为验证这一假设, 我们在一个长期维生素A 缺乏的人群中的妇女中研究了孕前、孕中及孕后补充维生素A 或β胡萝卜素对子女肺功能的远期影响。方法: 我们检查了尼泊尔农村9 ~13 岁的儿童, 这些儿童的母亲在1994 年至1997 年参加了一个补充维生素A 或β胡萝卜素、安慰剂对照、双盲组群随机抽样试验。结果: 在原试验结束时有1894 例儿童存活, 其中1685 例( 88% ) 符合纳入标准参加本研究进行随访。其中1371 例儿童( 纳入试验儿童的83% ) 在2006 年10 月至2008 年3 月期间进行了肺功能测定。在校正身高、性别、年龄、体重指数、历月、种族及肺功能仪等因素后, 母亲服用维生素A 的儿童FEV1 和FVC 均显著高于母亲服用安慰剂的儿童( FEV1 : 维生素组高46 mL,95% CI 6 ~86; FVC: 维生素组高46 mL, 95% CI 8 ~84) 。而服用β胡萝卜素的研究对象肺功能与安慰剂组相似( FEV1 :β胡萝卜素组高14 mL, 95% CI 24 ~54; FVC: β胡萝卜素组高17 mL, 95% CI 21 ~55) 。结论: 在长期营养不良的人群中, 孕前、孕中及孕后在孕妇食物中补充适当的维生素A 能改善其子女肺功能。这种改善带来的公共卫生的益处在儿童青春期前是明显的。 【述评】 维生素A 通过调节细胞的增殖和分化影响身体发育生长。动物实验证实维生素A 缺乏会可导致肺发育不良。本研究通过严格的临床科研设计证实在维生素A 缺乏的母亲中补充维生素A 可增加其子女FEV1 和FVC, 进一步表明维生素A 在肺发育中的重要作用。但是, 这种维生素A 补充对肺功能的远期影响, 包括成人后肺功能情况及老年后肺功能的减退的影响值得进一步研究。其次, 这种肺功能改善对儿童及成人呼吸系统疾病, 包括哮喘、COPD、支气管扩张症等的发生是否具有影响也值得探讨。最后, 应进一步研究这种维生素A 补充与肺功能改善是否存在量效关系, 以提供最佳的补充剂量。

    Release date:2016-08-30 11:54 Export PDF Favorites Scan
  • 食管癌手术对游离脂肪酸和维生素A、E代谢的影响

    目的 探讨食管癌手术对脂肪和脂溶性维生素代谢产生的影响。方法 将52例食管癌患者和36例胸部良性疾病患者分成两部分,游离脂肪酸谱分析部分实验组:29例食管癌患者;对照组:19例胸部良性疾病患者。血清维生素A、维生素E(VitA 、VitE)测定部分实验组:23例食管癌患者;对照组:17例胸部良性疾病患者。所有病例均分别在术前1天,术后7天和30天进行5种游离脂肪酸(FFA)分析和VitA、VitE测定。结果 术前1天实验组和对照组亚油酸、油酸、硬脂酸、VitA、VitE差别均无显著性意义(P>0.05);实验组软脂酸、花生四烯酸明显升高(P<0.05)。术后7天实验组患者禁食输入脂肪乳剂后,花生四烯酸和Vit A、Vit E明显低于对照组(P<0.05),其余4种FFA差别无显著性意义(P>0.05)。术后30天,两组间5种FFA差别无显著性意义(P>0.05),而实验组患者仍停留在术后7天的低水平,显著低于对照组(P<0.05)。结论 食管癌患者术前已存在脂肪动员,术后7天在禁食期间输入脂肪乳剂是必要的,但仍不能满足患者对花生四烯酸和VitA、VitE的需求。手术30天后能正常进食的食管癌患者仍存在VitA、VitE的严重不足,有从静脉补充的指征;而5种FFA可达到正常水平。低脂肪、高糖和高蛋白质才是合理的膳食结构。

    Release date:2016-08-30 06:34 Export PDF Favorites Scan
8 pages Previous 1 2 3 ... 8 Next

Format

Content