目的 探讨缺血性脑血管病患者高同型半胱氨酸(Hcy)血症与颅内外动脉狭窄的关系。 方法 2007年6月-2009年12月收治缺血性脑血管病患者90例，根据全脑血管造影检查结果分为颅内外动脉狭窄组和颅内外动脉无狭窄组；颅内外动脉狭窄组依狭窄部位分为单纯颅内动脉狭窄组、单纯颅外动脉狭窄组及颅内外动脉均有狭窄组；分析各组同型半胱氨酸的水平。 结果 颅内外动脉狭窄组血浆Hcy水平显著高于颅内外动脉无狭窄组(Plt;0.05)；单纯颅内动脉狭窄组、单纯颅外动脉狭窄组及颅内外动脉均有狭窄组血浆Hcy水平均显著高于颅内外动脉无狭窄组(Plt;0.05)。 结论 高同型半胱氨酸血症是颅内外动脉狭窄的危险因素，是单纯颅内动脉狭窄及单纯颅外动脉狭窄的共同危险因素。
ObjectiveTo analysis the risk factors for carotid stenosis in patients with ischemic cerebrovascular disease based on digital subtraction angiography. MethodsA total of 312 patients diagnosed with ischemic cerebrovascular disease who underwent digital subtraction angiography from June 2011 to September 2013 were selected.The risk factors of carotid stenosis were analysised by multivariate logistic regression analysis. ResultsIn 312 patients,271 were with cerebral infarction and 41 were transient ischemic attack patients.There were 149 patients in carotid stenosis group (stenosis degree ≥50%) and 163 patients in control group (stenosis degree<50%).The age (OR=1.037,P=0.000) and coronary heart disease (OR=4.121,P=0.001) were independent risk factors of carotid stenosis with ischemic cerebrovascular disease. ConclusionCarotid stenosis is common in ischemic cerebrovascular disease.Age and coronary heart disease were the independent risk factors.The recognition and control of these risk factors are in favor of secondary prevention of ischemic cerebrovascular disease.