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find Author "肖锋" 4 results
  • Comparison of Accuracy of Different Renal Function Measurements for Predicting Adverse Events after Off-pump Coronary Artery Bypass Grafting

    Objective To compare the accuracy of different renal function measurements for predicting postoperativeadverse events after off-pump coronary artery bypass grafting (OPCAB) for Chinese patients. Methods Clinical data of 283 Chinese patients undergoing isolated OPCAB from January 2010 to December 2011 in the First Hospital of Peking University were retrospectively analyzed. There were 194 male and 89 female patients with their age of 65.0±9.7 years. Estimated glomerular filtration rate (eGFR) was calculated using Cockcroft-Gault equation,Modification of Diet in Renal Disease (MDRD) study equation and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation respectively.Logistic multivariate regression analysis was performed to compare the accuracy of these 3 different renal function measure-ments for predicting postoperative adverse events. Results Logistic multivariate regression analysis showed that preoper-ative renal dysfunction was an independent risk factor for higher postoperative morbidity,more blood transfusion,prolongedhospitalization,mechanical ventilation time and length of ICU stay. Among the different postoperative complications,preop-erative renal dysfunction was an independent risk factor for postoperative acute renal injury,gastrointestinal bleeding,new onset atrial fibrillation and low cardiac output syndrome. Among Cockcroft-Gault equation,MDRD study equationand CKD-EPI equation to calculate eGFR,CKD-EPI equation was most accurate to predict postoperative morbidity (OR=1.227),acute renal injury (OR=1.534),new onset atrial fibrillation (OR=1.184),prolonged hospitalization(OR=1.160),mechanical ventilation time (OR=1.165) and ICU stay (OR=1.151). Conclusion Preoperative renal dysfunction is an independent risk factor for postoperative adverse events after OPCAB. CKD-EPI equation is more suitable for predicting postoperative adverse events after OPCAB for Chinese patients.

    Release date:2016-08-30 05:47 Export PDF Favorites Scan
  • The Era of Drug-Eluting Stents--the Change of Coronary Artery Bypass Grafting Conduit

    Drug-eluting stents have great impact to the coronary artery bypass grafting(CABG) in cardiac surgery. Someone even believes that it could replace the surgery procedure. However, the drug-eluting stents are not so ideally in the clinic practice. There are no significant difference between drug-eluting stents and bare metal stents in the mortality and the angina recurrence in middle-long term follow-up. The same results are in the compare with the CABG. As the challenge of the drug-eluting stents, the cardiac surgery has many aspects practice and progress in the harvest of the bypass graft. In the article, the change of the CABG conduit in the era of drug-eluting stents are reviewed.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • 术中自体血液回收对体外循环术后全身性炎性反应的影响

    目的 探讨在体外循环手术中使用洗涤式自体血液回收机(ATS)对术后全身性炎性反应的影响.方法 将择期体外循环冠状动脉旁路移植术(CABG)的12例患者随机分为两组(每组6例),实验组:将手术野渗血和停机后机血混合经ATS处理后回输;对照组:将停机后机血直接回输.于围手术期测定两组补体终末复合物(sC5b-9)、白细胞介素-6(IL-6)等炎性因子指标.实验组分别测定ATS处理前后炎性因子指标. 结果 实验组回收血经ATS处理后红细胞压积(HCT)明显升高(Plt;0.01),sC5b-9、肿瘤坏死因子-α(TNF-α)和IL-6水平显著降低(Plt;0.05).停机6小时、24小时和48小时,实验组sC5b-9变化率均低于对照组(Plt;0.05),停机48小时,实验组IL-6变化率低于对照组(Plt;0.05),术后两组TNF-α水平以及变化率差别无显著性意义;停机48小时,实验组中性粒细胞(PMN)显著低于对照组(Plt;0.01). 结论 在体外循环手术中使用ATS回收术野渗血和停机后机血可以去除绝大部分炎性介质,回输后可以降低术后部分炎性介质的水平,减轻体外循环术后的炎性反应.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Coronary Artery Bypass Grafting Using Arterial Conduits

    Objective\ To search for suitable and multiple arterial grafts for myocardial revascularization, in order to avoid the long term problems of vein graft atherosclerosis. Methods\ Between October 1994 and April 2000, 456 consecutive patients underwent myocardial revascularization using radial artery and internal mammary artery. In coronary artery bypass grafting, minimally traumatic harvesting radial artery techniques and new pharmacologic antispasmodic agents was used. Results\ 448 internal mammary artery ...

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
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