【摘要】目的 探讨纤维胆道镜对肝胆管狭窄的诊治价值。 方法 对45例肝胆管狭窄患者进行纤维胆道镜诊治，总结分析其方法的优越性。根据不同狭窄类型，治疗采取活检钳撕破狭窄膜或镜身扩张法、球囊扩张加支架支撑法。 结果 所有病例均成功治愈，无一例出现明显并发症。 结论 纤维胆道镜治疗胆管狭窄具有微创、安全、有效及方便等优点，是治疗肝胆管狭窄的有效手段。
近年来，胆石症的发病谱已发生了根本性的变迁，一些大城市的胆囊结石发病率逐步增加，过去常见的肝内胆管结石已明显减少； 但多数地区肝内胆管结石发病率仍较高，仍是我国的常见病之一，其治疗也仍是胆道外科中的困难问题。运用现代肝脏外科手术技术，处理肝门部和肝内胆管及血管，获得良好的显露，基本上可达到“解除梗阻，去除病灶，通畅引流”的肝胆管结石外科治疗原则。由于肝内胆管结石本身的复杂性，目前尚无一种手术方式可使所有患者获得满意效果，因此，应根据患者的实际情况采用“个体化治疗方案”。常用的手术方法有胆管探查取石、胆肠引流、肝叶切除术等。根据病情、患者的身体素质、技术条件和病变的性质等综合考虑来决定术式。
目的探讨肝内胆管结石合并肝胆管癌的临床诊断和治疗经验。 方法回顾性分析我院手术治疗28例肝内胆管结石合并肝胆管癌的病例资料。结果本组28例占同期肝内胆管结石病例的6.7%。术前各类影像学检查发现癌灶17例，5例获细胞学检查确诊。术中7例经快速组织活检证实。另4例系术后确诊。肿瘤多为腺癌，位于肝门胆管18例，肝内胆管9例，肝内、肝门部广泛浸润1例。根治性肿瘤切除8例，获随访6例，平均生存23个月； 姑息性肿瘤切除8例，获随访6例，平均生存11个月； 仅行外引流者7例，其中3例于术后2周内死亡，3例术后9个月内死亡，1例生存4个月后失访。结论长期肝内胆管结石刺激及继发感染是肝胆管癌发生的重要因素。联合应用影像学检查结合病理活检获得早期诊断和选择合理的根治性肝切除术是提高疗效的有效措施。
目的 减少肝内胆管结石术后的残留。方法 回顾性分析近5年我科收治的50例肝内胆管结石病例行病灶肝切除并结合术中、术后胆道镜应用的近期疗效及术后残石率。结果 术后近期并发症发生率为8%，无胆漏、肝衰及手术死亡发生，术后B超、逆行T管造影及术后胆道镜检查证实的即期残石率仅4%（2例）。结论 减少肝内胆管结石术后结石残留的关键是术中术后胆道镜的使用，肝内及肝门胆管狭窄的彻底处理； 依据狭窄胆管所引流区域行“根治性”的肝组织切除是取尽结石，清除病灶的合理方法。
From December 1981 to October 1997, we had performed 1559 cases of intrahepatobiliary tract stones by surgery alone/or with cholangioscopy, of which 332 cases were left intrahepatobiliary tract stones (accounted for 33.9%), 111 right intrahepatobiliary tract stones (accounted for 11.3%) and 545 cases in both sides (54.7%). 324 patients complicated with stricture of biliary tract (32.3%), of which 156 cases (48.2%) were stricture of left intrahepatobiliary tract, 107 cases (33.0%) stricture of right intrahepatobiliary tract, 61 cases (18.8%) stricture of hepatic hilus biliary tract. The operative procedure were: ①hapatic lobe or segment resection, ②high cholangiotomy and palstic repair, ③choledochojejunostomy and ④T-tube or U-tube drainage with removal of stones by cholangioscopy later. The operative procedure should be based on different types of intrahepatobiliary tract stones and patholigical features. The result indicates that cholangioscopy may play an important role in the treatment of intrahepatobiliary tract stones.
An retrospective analysis of 112 cases with localized left hepatolithiasis (LLH) treated in our center in recent two decades was made. The results showed: ①Coexisting involvements of both left external hepatic duct (LEHD) and left medial hepatic duct (LMHD) were the most common pathological pattern (83.08%), came next the only LEHD involvement (12.31%). There was no localized LMHD caculi in this group. ②The rate of concomitant LHD stricture was 59.82% and that of LMHD or LEHD were 84.85% and 84.00% respectively, in which severe degrees dominate. ③Lateral segmentectomy was the most common clinical practice for LLH (58.93%), and left lebectomy was much less frequently used (12.50%), although the latter led to a significantly smaller rate of residual (7.14% vs 21.21%) and had a satification follow-up rate of 85.71% being superior to lateral segmentectomy (46.97%), or cholangiojejunostomy (40.00%), bile duct exploration and drainage (0). ④The most common prognostic factors were residual or recurrent stones of LMHD (62.50%) and residual LHD stricture (37.50%). ⑤There was no significant difference between left lobectomy and lateral segmentectomy in length of operation, intraoperative bleeding, and postoperative complications. The results indicate that too much dependence on lateral segmentectomy in the management of LLH is one of the most important factors affecting the longterm results, for which left lobectomy is an applicable and safe therapy of choice.