目的 总结肺隔离症的临床特点、诊断方法及治疗的经验，降低误诊率，提高治疗水平。 方法 回顾性分析福州总医院2002年7月－2012年6月收治的27例肺隔离症患者的临床诊治手段。 结果 27例肺隔离症患者中，术前确诊仅有18例，误诊为肺部良性肿瘤3例，肺脓肿3例，支气管扩张2例，纵隔肿瘤1例。行外科切除的患者有19例，其中13例经胸腔镜手术，6例开胸手术，均无复发；行支气管动脉数字减影血管造影栓塞术8例，其中再发咯血1例来院行手术治疗。 结论 外科治疗是目前肺隔离症治疗的主要方法。围手术期积极控制感染对治疗的成功有显著意义。
ObjectiveTo explore the safety and feasibility of uni-portal video-assisted thoracic surgery (VATS) for the treatment of bronchopulmonary sequestration (BPS). MethodsThe clinical data of BPS patients with surgical resection in Shanghai Pulmonary Hospital from February 2010 to June 2021 were reviewed. The patients were divided into a VATS group and a thoracotomy group according to the operation method. The operation time, intraoperative blood loss, hospital stay and postoperative complication rate were compared between the two groups. The VATS group was subdivided into a uni-portal VATS group and a multi-portal VATS group for subgroup analysis. ResultsFinally 131 patients were enrolled, including 62 males and 69 females with an average age of 39.3±13.2 years. There were 103 patients in the VATS group and 28 patients in the thoracotomy group. A total of 104 patients were diagnosed with left lower BPS, 26 with right lower BPS and 1 with bilateral lower BPS. The main symptom was cough (88 patients, 67.2%). There were 119 patients diagnosed by thoracic enhanced CT before operation. Compared with the thoracotomy group, the operation time was not statistically different (P=0.717), but the blood loss was less, the rate of postoperative complication was lower and hospital stay was shorter in the VATS group (P＜0.05). The rate of conversion to open surgery in the uni-portal VATS group and multi-portal VATS group was 11.8% and 13.5%, respectively. Meanwhile, patients in the uni-portal VATS group had shorter operation time and postoperative hospital stay, less blood loss and lower postoperative complication rate than those in the multi-portal VATS group (P＜0.05). Conclusion In order to improve the rate of diagnosis, the lung enhanced CT scan should be selected as an optimal noninvasive method in adult suspected patients (especially those with solid cystic and solid lesions in the lower lobe). Uni-portal VATS is a safe and feasible method for BPS which can be widely promoted.
【摘要】 目的 分析总结肺隔离症（PS）的临床诊断及治疗方法。 方法 回顾分析2000年2月-2009年10月确诊的27例PS患者临床特征、诊断方法及治疗手段。 结果 27例PS患者均经影像学和手术确诊，其中叶内型22例，叶外型5例，行左下肺切除17例，右下肺切除10例；全部手术切除。术后并发胸腔积液1例，肺不张2例，分别给予穿刺抽液、纤维支气管镜吸痰等积极治疗后痊愈，其余患者恢复较好，随访6~60个月无复发。 结论 PS手术前误诊率高，诊断方法主要为X线平片、CT及CT增强血管照影（CTA）检查。CTA可显示异常供血动脉，是诊断PS的首选检查方法。一经明确诊断应尽早给予治疗，治疗方案主要包括手术和螺圈栓塞。【Abstract】 Objective To summary the diagnosis and therapy of pulmonary sequestration. Methods Clinical symptoms, methods of diagnosis and treatments of 27 patients diagnosed with pulmonary sequestration from February 2002 to October 2009 were analyzed retrospectively. Results Twenty-seven patients were all confirmed by imaging and surgery, and had undergone surgical excision. Twenty-two patients were with intralober pulmonary sequestrateon (IPS) and five were with extralober pulmonary sepuestration (EPS); 17 patients were treated by left lower lobectomy, and 10 patients required right lower lobectomy. After the surgery, there were one patient with pleural effusion and two patients with atelectasis who suffered from complications postoperatively, and they were healed by symptomatic treatment. The rest recovered well. There were no recurrence from six to 60 months follow-up. Conclusion Pulmonary sequestration may be misdiagnosed easily. The main methods for the examination include X-ray,CT and CTA. CTA can detect anomalous systemic artery,which should be the first choice in diagnosing of pulmonary sequestration. Surgery and coil embolization are the main treatments. Once being confirmed,pulmonary sequestration should be treated as soon as possible.