Objective To systematically review the effectiveness and safety of single-incision laparoscopic cholecystectomy (SILC) versus conventional multiport laparoscopic cholecystectomy (CMLC). Methods We electronically searched PubMed, EMbase, The Cochrane Library (Issue 1, 2013), CBM, CNKI, VIP and WanFang Data for randomized controlled trials (RCTs) on SILC versus CMLC from inception to January 1st, 2013. According to the Cochrane methods, the reviewers screened literature, extracted data, and assessed the methodological quality. Then, meta-analysis was performed using RevMan 5.2 software. Results Finally, 17 RCTs involving 1 233 patients were included. The results of meta-analysis showed that, compared with CMLC, SILC was lower in 24 h postoperative pain score (visual analogue scale, VAS) (SMD= –0.40, 95%CI –0.76 to –0.04, P=0.03), higher in cosmetic results score (SMD=1.56, 95%CI 0.70 to 2.43, P=0.000 4), and longer in operative time (MD=13.11, 95%CI 7.06 to 19.16, Plt;0.000 1). However, no significant difference was found in 6 h postoperative pain scores (VAS), postoperative complications, port-site hernia and hospital stay between the two groups. Conclusion SILC is a safe and effective technique for the treatment of uncomplicated benign gallbladder diseases, and it has certain advantages compared with CMLC, which is recommended in clinical application.
目的 探讨经腹部彩色多普勒超声（腹部超声）联合高频超声诊断良性胆囊息肉样病变的价值。 方法 回顾性分析2008年1月－2011年11月121例腹部超声联合高频超声检查提示为良性胆囊息肉样病变、且有手术病理检查结果的患者资料进行对照，以此评价经腹部超声联合高频超声对良性胆囊息肉样病变的诊断准确性。 结果 121例术前经腹部超声联合高频超声诊断为良性胆囊息肉样病变的患者，手术后病理检查结果示胆固醇息肉62例（51.24%），炎性息肉27例（22.31%），腺瘤6例（4.96%），腺癌3例（2.48%），胆囊结石14例（11.57%），腺肌症3例（2.48%），囊壁腺体结构紊乱3例（2.48%），黏膜下层软结节3例（2.48%）。经腹部超声联合高频超声与手术后病理对比检查，其诊断符合率为78.51%（95/121），误诊率为21.49%（26/121）。 结论 经腹部超声联合高频超声检查对良性胆囊息肉样病变诊断准确性较高，可为临床预防胆囊癌前病变提供依据。Objective To investigate the value of abdominal color Doppler ultrasonography (CDU) combined with high-frequency ultrasonography (HFU) diagnosing benign polypoid lesion of gallbladder (B-PLG). Methods A total of 121 patients with B-PLG diagnosed by CDU combined with HFU between January 2008 and November 2011 were randomly selected. All of the patients underwent the surgery and had the record of surgical pathological examination results, which were compared with the results of the ultrasonography in order to evaluate the diagnostic accuracy of CDU combined with HFU for B-PLG. Results In 121 patients with B-PLG diagnosed by CDU combined with HFU before the surgery, cholesterol polyp was found in 62 (51.24%), infective polyp was found in 27 (22.31%), adenoma was found in 6 (4.96%), adenocarcinoma was found in 3 (2.48%), gallstones was found in 14 (11.57%), adenomyosis was found in 3 (2.48%), the wall structure gland disorder was found in 3 (2.48%), and submucosal soft nodules was found in 3 (2.48%) after the surgical pathological examination. Coincidence rate between CDU combined with HFU diagnosis and surgical pathological diagnosiswas 78.51% (95/121), and the misdiagnosis rate of CDU combined with HFU was 21.49% (26/121). Conclusion The accuracy of CDU combined with HFU diagnosing B-PLG is high, which can help to prevent precancerous lesion of gallbladder cancer.
【摘要】 目的 评估罗哌卡因切口预注射联合曲马多对腹腔镜下胆囊切除术（laparoscopic cholecystectomy，LC）术后疼痛的影响。 方法 选取2010年6月-2011年4月行择期LC患者120例，年龄18~65岁，美国麻醉师协会Ⅰ~Ⅱ级，采用完全随机的设计分组：0.75%罗哌卡因10 mL切口注射+术毕静脉注射曲马多（2 mg/kg）组（A组，n=30）；生理盐水10 mL切口注射+术毕静脉注射曲马多（2 mg/kg）组（B组，n=30）；0.75%罗哌卡因10 mL切口注射+术毕静脉注射生理盐水10 mL组（C组，n=30）；生理盐水组（D组，n=30）。术后2、4、6、12、24 h分别评估右上腹部、右肩背部和腹壁切口疼痛进行视觉模拟评分（visual analog scale，VAS）。 结果 右上腹部及右肩背部疼痛VAS比较：与D组相比，A、B组VAS评分明显减少（Plt;0.05），而C组无明显统计学差异（Pgt;0.05）；B组与A组相比，2~24 h VAS评分明显增加（Plt;0.05）；C组与A组相比，2~24 h VAS评分增高（Plt;0.01）。腹壁切口疼痛VAS比较:与D组相比，A、B、C组VAS评分明显减少（Plt;0.05）；B组与A组相比，2~24 h VAS评分明显增加（Plt;0.05）；C组与A组相比，2~24 h VAS评分显著增高（Plt;0.01）。 结论 腹腔镜胆囊切除术术前切口罗哌卡因预注射-术毕曲马多静脉注射对减轻术后疼痛有良好效果。【Abstract】 Objective To evaluate the effects of preincisional ropivacaine plus tramadol intravenous injection on postoperative pain relief after laparoscopic cholecystectomy (LC). Methods One hundred and twenty patients aged between 18 and 65 years old with an ASA score from Ⅰ to Ⅱ who underwent elective laparoscopic cholecystectomy from June 2010 to April 2011 comprised this study. The patients were randomly divided into four groups with 30 in each group. Patients in group A had an infusion of 0.75% ropivacaine (10 mL) at the beginning of LC plus tramadol (2 mg/kg) intravenous injection at the end. Group B patients had an infusion of normal saline 0.9% (10 mL) at the beginning of LC plus tramadol (2 mg/kg) intravenous injection at the end. Patients in group C had an infusion of 0.75% ropivacaine (10 mL) at the beginning of LC plus normal saline 0.9% (10 mL) intravenous injection at the end. Group D (control group) patients had neither ropivacaine nor tramadol infusion. Pain in the right upper abdomen, right shoulder tip and abdominal incision were assessed at hour 2, 4, 6, 12, and 24 postoperatively using a visual analog score (VAS). Results Right upper abdomen and right shoulder tip pain VAS comparison: significantly lower pain scores were observed in group A and B (Plt;0.05) than in group D (Pgt;0.05). Group A had significantly lower pain scores than group B (Plt;0.05) and C (Plt;0.01) at postoperative hours 2, 4, 6, 12, and 24. Abdominal incision pain VAS comparison: VAS scores were significantly lower in group A, B and C than in group D (Plt;0.05). Group A had significantly lower pain scores than group B (Plt;0.05) and C (Plt;0.01) at postoperative hours 2, 4, 6, 12, and 24. Conclusion Preincisional ropivacaine at the beginning of LC combined with tramadol intravenous injection at the end can effectively alleviate postoperative pain after laparoscopic cholecystectomy.
【摘要】 目的 总结腹腔镜胆囊切除术（laparoscopic cholecystectomy，LC）治疗结石嵌顿性急性胆囊炎的疗效。 方法 2001年8月-2009年11月，采用LC治疗187例结石嵌顿性急性胆囊炎。 结果 179例顺利完成 L C手术；8例术中改为开腹手术。其中3例术后发生胆瘘，均经乳胶管引流胆汁，7～14 d后拔管；其余患者均痊愈出院。 结论 LC治疗结石嵌顿性急性胆囊炎安全可行，但应遵循个体化原则，熟练镜下操作技巧及正确处理方法是获得满意疗效关键。
【摘要】 目的 探讨经脐单孔腹腔镜胆囊切除术的临床可行性及其优缺点。 方法 回顾分析2010年7-9月行经脐单孔腹腔镜胆囊切除术34例患者临床资料。 结果 患者均顺利完成单孔腹腔镜胆囊切除术，手术平均时间为65 min，术后平均住院时间为3 d，术后未发生出血、感染、胆瘘等并发症。 结论 单孔腹腔镜胆囊切除术是安全可行的，术后腹部无明显瘢痕，美容效果明显。【Abstract】 Objective To evaluate the feasibility and value of the trans-umbilical single-port laparoscopic cholecystectomy. Methods The clinical data of 34 patients who underwent trans-umbilical single-port laparoscopic cholecystectomy from July to September 2010 were retrospectively analyzed. Results The operations of 34 patients were successfully performed. The mean operative duration was 65 minutes, and the mean duration in hospital after the operation was 3 days. No infection, postoperative bleeding, and biliary leakage occurred postoperatively. Conclusion Trans-umbilical single-port laparoscopic cholecystectomy is safe and feasible with good cosmetic effect.
目的:探讨腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)治疗急性结石嵌顿性胆囊炎的可行性。方法:总结分析2007年10月至2009年6月36例急性结石嵌顿性胆囊炎行腹腔镜胆囊切除术的经验体会,包括手术适应证及手术技巧等。结果:35例(972％)成功完成腹腔镜胆囊切除术,1例(28％)中转开腹,无胆管、肠管损伤,无术后出血及围手术期(术后30天)死亡等并发症,均获治愈。术后随访4月～23月无手术并发症。结论:在术者熟练的操作技巧,合理选择中转开腹时机的前提下,急性结石嵌顿性胆囊炎行腹腔镜胆囊切除术安全、可行。
目的：探讨胆囊癌肝侵犯的CT诊断及临床价值。方法：回顾性分析经手术、病理证实的17例胆囊癌肝侵犯CT资料。结果：肿块型11例，腔内型2例，厚壁型4例。侵犯肝左内叶5例，肝右叶前段3例，同时侵犯肝左内叶及右叶前段9例。5例侵犯深度＜2 cm，12例侵犯深度＞2 cm。CT表现为胆囊窝脂肪间隙消失，邻近胆囊窝的肝脏组织内出现不规则形低密度影，边界模糊，胆囊癌肿与肝脏组织分界不清，增强后肝内病灶不规则强化。结论：CT对胆囊癌肝侵犯的诊断及临床分期、治疗方案的选择具有重要价值。