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find Keyword "脑炎后癫痫" 2 results
  • A clinical study based on SEEG: epileptogenic mapping and surgery in pharmaco-resistant post-encephalitic temporal lobe epilepsy

    ObjectivesPost-encephalitic epilepsy could be of great chance of pharmaco-resistant, even surgery may not achieve seizure free. The aim of this study is to mapping epileptogenic area of pharmaco-resistant post-encephalitic temporal lobe epilepsy, to find whether "temporal plus" epilepsy is the main type and its surgery outcome, based on stereo-EEG(SEEG) study.MethodWe retrospectively studied 15 patients with pharmaco-resistant temporal lobe epilepsy. Scalp EEG, seizure semiology, MRI, FDG-PET, and SEEG were reviewed for all patients. According to epileptogenic area which was analysed by SEEG, 15 patients were divided into 2 groups, temporal lobe epilepsy(TLE) group and temporal plus epilepsy(TPE) group. Clinical characteristics were compared with each group, by t-test or Fisher exact test when data needed.ResultsThere were 8 patients in TLE group, with 6 mesial TLE, 1 lateral TLE, 1 mesial-lateral TLE. And 7 patients in TPE group. Age of seizure onset (P=0.548), duration of epilepsy (P=0.099), age of remote encephalitis (P=0.385), type of semiology (P=0.315) and lateralization of MR lesions (P=1.000), interictal FDG-PET hypometabalism (P=1.000) or intracranial implantation (P=0.619) were of no statistically difference between TLE group and TPE group. Surgery was performed in all patients. Better outcome was obtained in TLE group(5/8 class Ⅰ), and poor was in TPE group(3/7class Ⅰ).ConclusionMesial-TLE and temporal plus epilepsy were common types of pharmaco-resistant post-encephalitic TLE. There was no way to differentiate clinically, except by SEEG. Mesial-TLE had a better outcome after surgery, but temporal plus epilepsy did not.

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  • 脑炎后癫痫诊断与治疗进展

    脑炎后癫痫(Postencephalitic epilepsy,PEE)是指脑炎急性期后出现癫痫发作,是急性脑炎常见的后遗症,部分可发展为难治性癫痫。病毒感染引起的 PEE 是最常见类型。文章总结了 PEE 的病因、流行病学、发病机制,PEE 发生相关的危险因素以及用药指征,以期为该疾病的诊断、治疗及预后评估提供临床参考。

    Release date:2020-09-04 03:02 Export PDF Favorites Scan
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