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find Author "苏肇伉" 36 results
  • 先天性心脏病微创手术的发展趋势

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • 开展术后随访的困境和策略

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • 亟待提高我国复杂先天性心脏病外科治疗的质量

    Release date:2016-08-30 06:27 Export PDF Favorites Scan
  • Current Clinical Application of Ross Procedure

    Abstract:The use of pulmonary autograft was first reported in 1967 by Ross for the treatment of aortic valve disease in adults. Since that time, Ross procedure has been applied to a variety of forms of aortic stenosis and left ventricular outflow tract obstruction and mitral valve disease, Ross procedure has undergone several modifications, such as the root replacement method, inclusion cylinder technique, annular reduction, Konno root enlargement procedures and replacement of the mitral valve with a pulmonary autograft (Ross-Kabbani procedure or Ross Ⅱ procedure). Advantages of Ross procedure in women of childbearing age, children and young adults include freedom from anticoagulation, appropriate sizing, cellular viability with growth potential proportional to somatic growth, acceptable long-term durability, excellent hemodynamic performance and decreased susceptibility to endocarditis. Surgical technical aspects, indications, selection criteria for the Ross procedure and its modifications, their applicability in the surgical management of aortic stenosis, left ventricular outflow tract obstruction and mitral valve disease and clinical outcome of Ross procedure are reviewed in this article.

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • 双向上腔静脉肺动脉吻合术后并发肺动静脉异常的发病机制

    综述肺动静脉异常发生的病理机制.双向上腔静脉肺动脉吻合术后并发肺动静脉异常是患者术后紫绀进行性加重的主要原因之一,其发病机制一般认为与肺循环血流动力学、肝因子或肝静脉缺乏和低氧等因素有关.双向上腔静脉肺动脉吻合术后低于正常值的动脉血氧饱和度可刺激一些血管生成因子,如血管内皮生长因子和成纤维细胞生长因子的表达增加;肝静脉血被排除在肺循环以外,其内在的抑血管形成因子缺乏使血管重塑,最终导致肺动静脉异常的形成.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Bidirectional superior cavopulmonary anastomosis

    Bidirectional superior cavopulmonary anastomosis(BCPA)is a palliative method used in the single ventricular repair. It mainly includes bidirectional Glenn shunt and hemi-Fontan operation. The indications of BCPA are those as an intermediate option of total cavopulmonary anastomosis, partial biventricular or 1 1/2 ventricle repair and a practical approach to complex congenital heart surgery. The choise of age,influence on pulmonary artery maturation,remain of additional pulmonary flow,formation of collaters and time to Fontan are demand of study.

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • Advances of operative technique for several complex congenital heart disease

    At present, the operative results of complex congenital heart disease are suboptimal which is closely correlated to the understanding of the anatomy and function of complex congenital heart disease, and operative techniques. With the further understanding to pathology and physiology of congenital heart disease, strategies and techniques in well-known operations and complex procedures have developed in recent years. Currently, designing and applying individual operative method in terms of patient’s characteristics of anatomy and physiology is very important trend. This article reviewed the advances of knowledgement and techniques in some representive complex congenital heart disease including complete atrioventricular septal defect, unifocalization for major aortopulmonary collateral arteries, transopsition of the great artery and Fontan type operation.

    Release date:2016-08-30 06:27 Export PDF Favorites Scan
  • Cryopreserved Homograft Pericardium Patch in Staged Repair of Tetralogy of Fallot

    Objective To compare the difference of effect while using homograft pericardium patch and Gore- tex patch in staged repair of tetralogy of Fallot(TOF) to enlarge the right ventricular outflow tract (RVOT). Methods Twenty-eight patients with TOF who underwent the staged complete repair were divided into 2 groups according to the date of surgery. Gore-rex group, 13 cases, their RVOT were enlarged with Gore-tex patches. Cryopreserved homograft pericardium patch group, 15 cases, their RVOT were enlarged with cryopreserved homograft pericardium patches. Clinical results and follow-up results were compared. Results There were 1 operative death in Gore-tex patch group (7. 7%), and 1 early postoperative death in cryopreserved homograft pericardium patch group (6. 7%). Hemostasia time, the pericardial cavity drainage volume in cryopreserved homograft pericardium patch group were less than those in Gore-tex patch group (P〈0. 01). All patients were followed-up for 0.8-4.5years. The residual obstruction rate at RVOT level in Gore-tex patch group was higher than that in cryopreserved homograft pericardium patch group by echocardiography (P〈0.01). No calcification shadow was found on the chest X-ray. Conclusion Homograft pericardium is the tissue with high density and intensity, its elasticity and compliance are good. Using homograft pericardium patch may be helpful to decrease the residual obstruction of RVOT after operation. It can be adapted as a repairing material in heart surgery.

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • 一期手术纠治主肺动脉窗及伴发畸形

    目的 总结一期手术纠治主-肺动脉窗及伴发畸形的临床经验,以提高手术疗效。 方法 我科共收治26例主-肺动脉窗患者,男14例,女12例;年龄1.4±1.6岁;体重7.8±3.8kg。其中单纯主-肺动脉窗8例,合并主动脉弓中断、右肺动脉异常起源于主动脉、法洛四联症、房间隔缺损、室间隔缺损、二尖瓣反流和气管狭窄等18例。25例患者一期手术经主动脉切口补片关闭瘘口纠治主-肺动脉窗,同时纠治伴发的畸形;1例放弃治疗。 结果 全组无手术死亡。2例伴主动脉弓中断、动脉导管未闭和右肺动脉起源于升主动脉的新生儿术后3d延迟关胸;1例术后出血,3h后再次开胸止血。术后随访22例,随访时间1个月~4年。所有患者无明显的主动脉瓣上狭窄和肺动脉分支狭窄,2例残留轻度二尖瓣反流,1例残留轻至中度二尖瓣反流。 结论 主-肺动脉窗患者早期易发生肺动脉高压,一经诊断应立即手术。手术方式首选修补主肺动脉窗及一期纠治伴发畸形。尽管主-肺动脉窗可合并各种心内外畸形,但早期手术纠治可获得较好的中长期疗效。

    Release date:2016-08-30 06:09 Export PDF Favorites Scan
  • L-精氨酸对乳猪深低温停循环脑代谢与结构的影响

    目的 通过深低温停循环(DHCA)转流模型,研究左旋精氨酸(L-arg)在低温缺血时对脑代谢和结构的影响. 方法 采用上海种白猪,3~4周龄,随机均分成4组: L-arg组,左旋硝基精氨酸甲酯(L-NAME)组, L-arg+L-NAME组和对照组,每组10只.按临床方法行心肺转流术,于转流前、降温末、复温末和转流结束等分别测定颈内静脉一氧化氮(NO)、脑皮质三磷酸腺苷(ATP)和颈内静脉乳酸含量.并行脑组织学和超微结构观察. 结果 降温末L-NAME组和对照组NO含量较其它两组明显下降(Plt;0.01).复温末,除L-NAME组外,其余3组均恢复至转流前水平(Plt;0.01),L-arg组NO水平在复温末较转流前高(Plt;0.01). 转流开始后大脑皮质ATP即有明显下降,L-arg组下降幅度最小,且在复温末已接近转流前水平;L-NAME组下降幅度最大(Plt;0.01). 转流开始后颈内静脉乳酸含量即升高,L-arg组和L-arg+L-NAME组上升幅度较小;降温末和转流结束乳酸含量较其它两组低(Plt;0.01). 大脑皮质组织学和超微结构检查显示,大脑皮质细胞结构变化L-arg组和L-arg+L-NAME组较对照组和L-NAME组轻. 结论 深低温停循环手术时,应用L-arg具有较好的脑保护作用,而L-NAME有脑损害作用.L-arg可部分逆转DHCA时L-NAME对脑组织的损害作用.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
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