腹部实质脏器损伤的经典治疗原则是剖腹探查,及时的手术探查救治了不少腹部实质脏器损伤患者的生命，但也有不少本不需手术的患者遭受了剖腹手术的痛苦。随着基础和临床研究的进展，非手术治疗腹部实质脏器损伤已广泛用于临床，甚至超过了手术治疗。
Rupture is one of main complications of liver abscess. Seventy-seven patients with rupture of liver abscess are reviewed. Liver abscess may freely rupture into adjacent structures or organs or serous cavities and cause vatious complications. The causative factors of rupture of liver abscess in this series were late medical consultation in the course of the disease, delayed treatment due to misdiagnosis, and improper treatment. Measures that prevent rupture of liver abscess include raising clinical awareness of early diagnosis and timely effective drainage. The authors consider that transperitoneal surgical drainage is the best approach. Most patients with rupture of liver abscess should be treated by surgical drainage togather with transomental or transumbilital veno-catheterization for antibiotic infusion. Patients with rupture of liver abscess usually present a poor prognosis and a high mortality rate. The mortality in this group was 35.1%(27/77), which is closely related to the complications of the rupture of liver abscess.
Fifty-five patients with disorders of intestinal rotation (DIR) are reviewed. Dir can occur at any age. Twenty-nine adults and twenty-six children were treated in this group. The clinical manifestation is mainly that of intestinal obstruction, with an incidence of 85%. In this group, 11 patients were complicated with other congenital malformation, and the incidence was 20%. It is difficult to diagnose DIR from the clinical manifestation, but the definite diagnosis can be made by roentgenography in most patients. Surgery can treat the intestinal obstruction and associated malformation synchronously. The results of treatment were satisfactory.
目的:探讨Mirizzi综合症的诊断治疗特点，以提高其诊断和治疗水平。方法：对35例经手术证实为Mirizzi综合症的临床资料进行回顾性分析。结果:35例Mirizzi综合症患者中仅4例（11.4%）术前确诊。Ⅰ型7例，Ⅱ型17例，Ⅲ型9例，Ⅳ型2例。5例行胆囊切除术，2例行胆囊大部分切除术；胆囊切除、胆囊瓣瘘口修补6例，12例行胆囊切除、胆总管探查、瘘口修补、T管引流术；胆囊切除、胆肠吻合术10例。术后恢复好，随访结果，无严重并发症.结论：Mirizzi综合症术前确诊困难，B超结合MRCP/ERCP检查可以提高Mirizzi综合症的术前确诊率，手术容易损伤胆管，手术方式应据病理损伤程度决定。
ObjectiveTo observe the effect of 5Fluorouracil(5FU) on the exocrine pancreas. MethodsThe effects of 5FU were investigated in 8 patients who had undergone pancreatoduodenectomy. The pancreatic juice was temporarily diverted to the exterior via a pancreatic duct catheter.Ten days after operation,the patients were injected intravenously with 5FU 500 mg/d for three days. The samples of pancreatic juice were taken for measurement of amylase,pH, HCO3-, Na+, K+, Cl-, Ca2+ and Mg2+.ResultsThe amylase, pH, HCO3-, Na+, K+, Cl-, Ca2+ and Mg2+ did not alteredsignificantly before and after 5FU injection.Conclusion5FU has no shortterm effect on exocrine pancreas. Therefore, improvement of acute pancreatitis cannot be achieved through inhibiting pancreatic enzymes synthesis.
【Abstract】ObjectiveTo investigate the effect of high intensity focused ultrasound (HIFU) on the immunity of patients with advanced primary liver cancer (PLC). MethodsForty cases of PLC admitted to our institution from Mar. 2003 to Dec. 2003 were included in this study. Patients were divided into 2 groups and received either HIFU or radiofrequency ablation (RFA) treatment randomly. CD3, CD4, CD8, CD4/CD8, NK, IL-2, TNF were chosen to assess the immune status before and after treatment. The results were compared statistically. ResultsThe survival rate after HIFU was 80.0%, 61.1%, 42.9%, 33.3% at 3 months, 6 months, 9 months and 1 year respectively, which was similar to that after RFA treatment. The changes of immunity parameters of CD3, CD4, CD8, CD4/CD8, NK, IL-2 and TNF were not significant after HIFU treatment. In addition, the differences of those parameters between HIFU group and RFA group were insignificant. ConclusionThere are no detrimental effects on immunity in the early period after HIFU treatment.
目的 探讨脾脏原发性肿瘤的诊断与治疗方法。方法 对我院1996～2003年收治的22例脾脏原发性肿瘤患者的临床资料进行回顾性分析。结果 22例患者临床症状无特异性，术前均行B超检查，发现脾大21例，提示脾脏占位病变19例，该19例行CT检查，均发现脾大并提示有占位病变。手术病检证实良性肿瘤12例，恶性肿瘤10例。22例患者均行脾切除，其中有5例行淋巴结清扫，2例行侵犯脏器联合切除。结论 脾脏原发性肿瘤术前诊断主要靠B超、CT，其治疗首选外科手术。