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find Keyword "血小板输注" 4 results
  • Vitrectomy and autologous platelet concentrate for the treatment of idiopathic macular holes

    Purpose To assess the efficacy of pars plana vitrectomy,autologous platelet concentrate and gas tamponade for the treatment of full-thickness idiopathic macular holes. Methods The procedures consisted of pars plana vitrectomy with removal of posterior cortical vitreous,air-fluid exchange, instillation of autologous platelet concentrate onto the posterior pole and 20%~30%SF6 tamponade,were performed in treating 6 eyes of 6 patients with idiopathic macular holes. The patients were instructed to lie in a supine position for l hour after surgery,then adviced to remain in a facedown position for 2 weeks. Results Flattening of the surrounding retina and closure of the hole were achieved postoperatively in all the 6 affected eyes.Visual acuity improved two lines or more in 5 eyes (83.3%).Four eyes(66.7%)reached a postoperative visual acuity of 0.3 or more. Retinal detachment ocurred in one eye owing to peripheral new hole formation. Conclusion Pars plana vitrectomy, autologous platelet concentrate and gas tamponade for the treatment of full-thickness idiopathic macular holes are able to close macular hole and improve the visual acuity. (Chin J Ocul Fundus Dis,1998,14:14-15)

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • Using Evidence-Based Guideline for Prophylactic Platelet Transfusion in Patient with Myelodysplastic Syndrome

    To identify the best evidence in the management of indicator, short and long term of prophylactic platelet transfusion in patient with myelodysplastic syndrome (MDS). We searched the latest evidence-based guidelines in PubMed,reviewed and appraised these guidelines. Clinical decision was made based on the guidelines and the actual patient with MDS. Perfect treatment effect was obtained through evidence-based clinical decision.

    Release date:2016-09-07 02:25 Export PDF Favorites Scan
  • 130 例肺癌患者机采血小板输注疗效的分析

    目的 分析肺癌患者机采血小板的输注情况,探讨其疗效的影响因素及预防措施。 方法 收集 2010 年 1 月—2016 年 6 月 130 例肺癌患者输注机采血小板 205 例次的临床资料,根据血小板纠正增加指数来评价输注的临床疗效。从疾病类型、性别、年龄、体质量、血小板输注次数以及红细胞悬液输注情况对患者血小板输注疗效进行分析。 结果 130 例肺癌患者 205 例次血小板输注中,158 例次有效,其有效率为 77.1%;小细胞肺癌和非小细胞肺癌有效率分别为 81.5% 和 75.5%,差异无统计学意义(P=0.369);而非小细胞肺癌中的鳞状细胞癌和腺癌有效率分别为 82.3% 和 70.8%,差异无统计学意义(P=0.107);不同性别、年龄和体质量有效率差异无统计学意义(P>0.05);按血小板输注次数为第 1 次、第 2~4 次和第 4 次以上分组比较,有效率差异有统计学意义(P=0.022)。 结论 肺癌患者血小板输注次数可能是影响血小板输注疗效的因素,随着血小板输注次数的增加,发生血小板输注无效的可能性越大。

    Release date:2017-12-25 06:02 Export PDF Favorites Scan
  • The influence of perioperative autologous platelet transfusion on postoperative complications and prognosis of adult cardiac surgery patients: A systematic review and meta-analysis

    ObjectiveTo explore the effects of perioperative autologous platelet transfusion on postoperative complications and prognosis of adult cardiac surgery patient.MethodsUsing the method of systematic review of Cochrane Collaboration, we searched PubMed, Web of Science, EMbase, The Cochrane Library, CNKI and Wangfang databases, retrieving the literature from January 1970 to June 2020 to collect clinical randomized controlled trials on the effects of autologous platelet transfusion on complications and prognosis of adult cardiac surgery patients. The extracted valid data was analyzed by RevMan5.3 software.ResultsTen studies were included, with a total of 1 083 patients. The results of meta-analysis showed that there were statistical differences in the perioperative blood loss (MD=−195.15, 95%CI −320.48-−69.83, P=0.002) and perioperative blood transfusion (MD=−0.88, 95%CI −1.23-−0.52, P<0.001). There was no statistical difference in the death rate 30 days after the operation (RR=0.90, 95%CI 0.48-1.70, P=0.75), reoperations (OR=0.48, 95%CI 0.23-1.02, P=0.06), postoperative myocardial infarction (OR=1.29, 95%CI 0.48-3.51, P=0.61), postoperative infection (OR=1.71, 95%CI 0.89-3.29, P=0.11) or postoperative ICU retention time (MD=−0.31, 95%CI −0.67-0.05, P=0.09).ConclusionPerioperative autologous platelet transfusion can reduce perioperative blood loss and blood transfusion in adult cardiac surgery patients, but has no significant impact onprognosis and postoperative complications, which indicates that perioperative autologous platelet transfusion is a safe and beneficial blood protection measure for patients undergoing cardiac surgery.

    Release date:2021-07-02 05:22 Export PDF Favorites Scan
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