ObjectiveTo investigate the effectiveness of the tubal reconstruction after laparoscopic tubal pregnancy operation by comparing with simple laparoscopic tubal pregnancy operation. MethodsBetween May 2007 and May 2010, 63 patients with tubal pregnancy underwent laparoscopic tubal pregnancy operation and tubal reconstruction in 30 cases (trial group) or simple laparoscopic tubal pregnancy operation in 33 cases (control group). There was no significant difference in age, pregnancy time, and position between 2 groups (P gt; 0.05). The tube patency test and hysterosalpingography (HSG) were carried out to evaluate the efficacy. ResultsThe operation was successfully completed in 29 cases of trial group; 1 case had too severe adhesion to receive re-anastomosis and was excluded. The tube patency test showed that the tube was patency in 26 cases of trial group and in 2 cases of control group during operation, showing significant difference (Z=5.86, P=0.00); it was patency in 25 cases of trial group and in 26 cases of control group at 1 month after operation, showing no significant difference (Z=0.48, P=0.63). HSG examination showed tube was patency in 25 cases of trial group and in 2 cases of control group at 2 months after operation, showing significant difference (Z=5.35, P=0.00). After 24 months, intrauterine pregnancy of trial group (n=25, 86.20%) was significantly higher than that of control group (n=19, 57.58%) (χ2=7.72, P=0.01). ConclusionThe reconstruction after laparoscopic tubal pregnancy operation can significantly increase the intrauterine pregnancy rate, and it is better than simple laparoscopic tubal pregnancy operation.
目的 探讨腹腔镜下输卵管妊娠开窗取胚术后缝合与否对输卵管再通、宫内妊娠率的近期影响。方法 回顾分析2008年4月-2010年4月112例有保留生育功能意愿且具备随访条件的输卵管妊娠患者行腹腔镜手术的临床资料。根据手术方法将患者分为两组:A组54例,行患侧输卵管开窗取胚术,术后缝合输卵管;B组58例,行患侧输卵管开窗取胚术,术后不予缝合输卵管。两组术毕均予甲氨喋呤20 mg注射于病变输卵管处系膜,并行通液了解患侧输卵管通畅情况(对侧输卵管均通畅)。3个月后比较两组患侧输卵管的再通情况,并随访其近期(12个月内)宫内妊娠率、重复性异位妊娠率情况。 结果 A组54例患者术中患侧输卵管通畅48例,通而不畅6例;术后3个月B型超声监测下通液43例通畅,10例通而不畅,1例不通,通畅率79.63%。B组58例患者术中患侧输卵管通畅54例,4例通而不畅;术后3个月B型超声监测下通液37例通畅,13例通而不畅,8例不通,通畅率63.79%。近期(12个月内)宫内妊娠率、重复性异位妊娠率情况:A组54例,实访42例,宫内妊娠29例,占69.05%;重复性异位妊娠6例,占14.29%。B组58例,实访44例,宫内妊娠18例,占40.91%,重复性异位妊娠12例,占27.27%。A组术后患侧输卵管通畅率、宫内妊娠率高于B组,而重复性异位妊娠率明显降低,两组差异有统计学意义(P<0.05)。 结论 腹腔镜下输卵管妊娠开窗取胚术后行输卵管缝合,可以减少对患侧输卵管损伤并恢复其正常的解剖结构,从而有效地保留患者生育功能。术后患侧输卵管通畅率、宫内妊娠率明显高于术后不缝合者,而重复性异位妊娠率明显降低。