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氯喹中毒性视网膜病变一例

二尖瓣置换同期行双极射频消融术治疗风湿性二尖瓣病变合并心房颤动的疗效分析

目的分析二尖瓣置换同期行双极射频消融术治疗风湿性二尖瓣病变合并心房颤动的临床效果。 方法2009年6月至2012年6月成都军区总医院共收治风湿性二尖瓣病变合并心房颤动患者200例，其中男80例、女120例，年龄37～63（48.3±11.0）岁。根据是否同期行双极射频消融术将患者分为两组，试验组（n=100）患者瓣膜置换术同期行双极射频消融术，对照组（n=100）单纯行瓣膜置换术。 结果试验组体外循环时间和主动脉阻断时间较对照组均显著延长［（64.6±12.7）min vs.（60.8±10.8）min，P=0.024；（55.3±12.1）min vs.（49.8±10.5）min，P=0.001］，住院费用显著增加［（11.2±3.5）万元vs.（9.8±2.2）万元，P=0.001］，死亡率差异无统计学意义（2% vs.1%，P=0.561）。试验组在术毕、术后１年时的心房颤动转复率均显著高于对照组（82.0% vs.27.0%，72.9% vs.9.6%，P<0.05）。 结论二尖瓣置换同期行双极射频消融术治疗风湿性二尖瓣病变合并心房颤动患者是安全、有效的。

Fundus Analysis of Familial Exudative Vitreoretinopathy

ObjectiveTo observe and explore the fundus characteristics and fundus fluorescein angiography of familial exudative vitreoretinopathy (FEVR) in different stages. MethodsA total of 15 patients (23 eyes) diagnosed as FEVR in the West China Hospital of Sichuan University from January 2007 to November 2013 were included. Clinical data and reports of fundus exams and fundus fluorescein angiography (FFA) were retrospectively analyzed. ResultsOne eye (4.35%) was classified as stage Ⅰ, 10 eyes (43.48%) were classified as stage Ⅱ, 8 eyes (34.78%) were classified as stage Ⅲ, and 1 eye (4.35%) and 3 eyes (13.04%) were classified as stage Ⅳ and V, respectively. The outcomes of fundus exams showed that the number of peripheral retinal blood vessels increased, and vessels straightened as well as narrowed, especially in the temporal area. FFA showed blood vessels suddenly shut in the equatorial retina and peripheral non-perfusion areas were observed. ConclusionTypical fundus characteristics and fundus fluorescein angiography changes of FEVR can be observed in different stages. Comprehensive fundus exams and family history are helpful to confirm relevant diagnosis.