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find Keyword "过滤器" 5 results
  • Effects of DELP System in Treating Patients with Acute Cerebral Infarction

    目的:初步探讨体外血浆脂蛋白过滤器(DELP)对急性脑梗死患者的临床疗效及安全性。方法:采用随机、基础治疗平行对照试验设计,将符合入选标准的患者随机分为两组:试验组3例,发病48 h内和间隔一天上午接受DELP治疗,对照组2例,仅给予基础治疗。用NIHSS量表,Barthel指数和改良Rankin评分评价神经功能恢复状况。结果:治疗后14 d治疗组NIHSS降低趋势明显优于对照组,治疗后90 d治疗组mRS良好预后的患者比例显著高于对照组。两组均未发现明显不良反应,治疗前后两组的实验室指标无显著变化。结论:DELP治疗急性脑梗死所致的神经功能缺损效果及安全性良好,为临床急性脑梗死的治疗提供了一条新的途径。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • 肝素涂层与非肝素涂层动脉过滤器的临床对比观察

    目的 对肝素涂层和非肝素涂层动脉过滤器在体外循环术中的应用结果进行对比观察。方法 80例体外循环心脏直视手术患者随机分为两组,每组40例。A组:用肝素涂层动脉过滤器,B组:用非肝素涂层动脉过滤器;并于不同的时间点观察血小板计数、血红蛋白、红细胞压积、激活凝血时间和过滤器内网在电子显微镜下的改变。结果 转流60分钟和结束时血小板计数,A组高于B组(P〈0.05)。电子显微镜示A组网眼清晰,边缘清楚,偶见有块状过滤物,B组滤网有絮状物,散在分布于网眼边缘,模糊不清,堵塞网眼,表明有纤维蛋白聚集,血小板粘附,脱落形成血小板碎片。结论 肝素涂层动脉过滤器能改善其生物相容性。

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • 负压吸引终端过滤器的制作与应用

    目的寻找一种简便高效的负压终端过滤网清洗方法,以降低其堵塞对临床工作造成的影响。 方法依据负压吸引的使用习惯于2012年8月设计制作出外接型负压过滤器,并分别对原安装模式的过滤网和现外接型过滤网的清洗效率进行测试对比。 结果拆洗负压吸引终端内的过滤网平均耗时20 min 19 s,折洗外接型过滤器的过滤网则仅需1 min 3 s。 结论外接型过滤器使用方便,可明显提高维护清洗维护效率,值得推广应用。

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  • VisConnectome: an independent and graph-theory based software for visualizing the human brain connectome

    As a complex system, the topology of human’s brain network has an important effect on further study of brain’s structural and functional mechanism. Graph theory, a kind of sophisticated analytic strategies, is widely used for analyzing complex brain networks effectively and comparing difference of topological structure alteration in normal development and pathological condition. For the purpose of using this analysis methodology efficiently, it is necessary to develop graph-based visualization software. Thus, we developed VisConnectome, which displays analysis results of the brain network friendly and intuitively. It provides an original graphical user interface (GUI) including the tool window, tool bar and innovative double slider filter, brain region bar, runs in any Windows operating system and doesn’t rely on any platform such as Matlab. When importing the user-defined script file that initializes the brain network, VisConnectome abstracts the brain network to the ball-and-stick model and render it. VisConnectome allows a series of visual operations, such as identifying nodes and connection, modifying properties of nodes and connection such as color and size with the color palette and size double slider, imaging the brain regions, filtering the brain network according to its size property in a specific domain as simplification and blending with the brain surface as a context of the brain network. Through experiment and analysis, we conclude that VisConnectome is an effective visualization software with high speed and quality, which helps researchers to visualize and compare the structural and functional brain networks flexibly.

    Release date:2019-12-17 10:44 Export PDF Favorites Scan
  • Application of topical citrate acid anticoagulation in patients with severe acute pancreatitis after continuous renal replacement therapy

    Objective To investigate the difference of anticoagulant efficacy of heparin and citric acid during continuous renal replacement therapy (CRRT) in patients with severe acute pancreatitis, and analyze their effects of on filter life span, length of hospital stay and mortality. Methods Patients with severe acute pancreatitis in Intensive Care Unit of the First Affiliated Hospital of Hebei North University between January 2018 and July 2022 were retrospectively enrolled, and they were divided into heparin group (control group) and citric acid group (research group) according to anticoagulation methods. The differences of anticoagulant catheter blockage during CRRT, filter life span, length of hospital stay, and 90-day mortality between the two groups were analyzed. Results A total of 108 patients were enrolled, including 56 in the research group and 52 in the control group. In pre-CRRT treatment, the balance value of fluid intake and outflow in the research group was significantly lower than that in the control group (P<0.05). The 108 patients received 217 times of CRRT treatment totally, with a median length of treatment of 63 h (range 44-87 h). The severity of catheter blockage in the research group was lower than that in the control group (P=0.003). The filter life span was longer in the research group than that in the control group [42.5 vs. 29.0 h; hazard ratio=1.83, 95% confidence interval (1.23, 2.73), P<0.001]; in the comparison of 90-day mortality, there was no significant difference between the two groups (P>0.05). The mean use of filters in the research group was less than that in the control group (1.93±0.09 vs. 2.17±0.14, P<0.001). The downtime of CRRT due to filter life in the research group was obviously shorter than that in the control group [120 (0, 720) vs. 300 (0, 890) min, P=0.029], while the duration of CRRT in the research group was remarkably better than that in the control group [10.6 (4.9, 27.7) vs. 8.1 (3.6, 25.0) d, P=0.024], and the risk of filter replacement due to special conditons in the research group was lower than that in the control group (46.4% vs. 65.4%, P=0.048). There was no statistically significant difference in the length of intensive care unit hospitalization or total hospitalization between the two groups (P>0.05). Conclusion Both heparin and citric acid could assist the treatment of CRRT, while citric acid might be apt to improve local coagulation and systemic inflammatory response.

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