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find Author "遇涛" 4 results
  • 双侧颞叶癫痫的外科治疗策略

    单侧颞叶癫痫(Unilateral temporal lobe epilepsy,UTLE)是最适合外科手术的对象之一,手术疗效已得到肯定。但是仍有部分颞叶癫痫患者术后发作控制不理想,可能与致痫灶为双侧颞叶起源或颞叶附加癫痫综合征等因素相关。其中双侧颞叶癫痫(Bilateral temporal lobe epilepsy,BTLE)是临床治疗的难题,常常药物疗效差,而又不被建议外科治疗。然而,目前BTLE的诊断标准、发病率、以及外科治疗策略等方面仍不明确。文章对BTLE的临床概念、发生率、形成机制、临床特点、诊断依据、神经心理学检查及外科手术策略进行分析、探讨。结果显示,基于头皮发作间期、发作期脑电图(EEG)判定BTLE并不可靠,经过颅内电极发作期EEG记录后,部分患者可以诊断为UTLE,接受手术切除后,效果满意;部分患者的颅内EEG记录显示癫痫发作具有明显的偏侧倾向,也可以考虑切除性手术。高频(EEG)监测、神经影像学检查及神经心理学检查对BTLE的诊断和治疗策略也有重要意义。

    Release date:2017-09-26 05:09 Export PDF Favorites Scan
  • 高频刺激人类丘脑前核去同步化癫痫网络的研究

    Release date:2018-09-18 10:17 Export PDF Favorites Scan
  • Portable Epileptic Seizure Monitoring Intelligent System Based on Android System

    The clinical electroencephalogram (EEG) monitoring systems based on personal computer system can not meet the requirements of portability and home usage. The epilepsy patients have to be monitored in hospital for an extended period of time, which imposes a heavy burden on hospitals. In the present study, we designed a portable 16-lead networked monitoring system based on the Android smart phone. The system uses some technologies including the active electrode, the WiFi wireless transmission, the multi-scale permutation entropy (MPE) algorithm, the back-propagation (BP) neural network algorithm, etc. Moreover, the software of Android mobile application can realize the processing and analysis of EEG data, the display of EEG waveform and the alarm of epileptic seizure. The system has been tested on the mobile phones with Android 2.3 operating system or higher version and the results showed that this software ran accurately and steadily in the detection of epileptic seizure. In conclusion, this paper provides a portable and reliable solution for epileptic seizure monitoring in clinical and home applications.

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  • A clinical study on the presurgical localization of the epileptogenic zones for patients with insular/peri-insular cortex epilepsy

    ObjectiveTo evaluate the role of several examinations in the presurgical localization of insular/peri-insular cortex epilepsy (IPICE). MethodsThe data of patients with IPICE who were identified by resective surgery from 2011.1 to 2015.4 were retrospectively analyzed. The role of semiology, scalp EEG, MRI and magnetoencephalography (MEG)in the localization of epileptogenic zones for patients with IPICE were evaluated. Results18 patients were selected according to the criteria. The localization of IPICE was supported by semiology in 16 patients, supported by MRI in 6 patients, supported by MEG in 17 patients. In 12 patients with negative MRI, the dipoles were showed in insular/peri-insular area in 11 patients. The localization role of MEG for patients with IPICE is more obvious than that of MRI (P < 0.05). The MEG result played conclusive role in 9 patients. According to result of MEG, the plans of intracranial recording were canceled in 3 patients, and the plans of intracranial electrodes implanting were modified in 5 patients. The resective surgery involving the insular/peri-insular cortex was performed in all the 18 patients. During the follow-up of 12~48 months, seizure-free was reported in 11 patients, although 2 patients were missed. ConclusionThe combination of the results of semiology, scalp EEG, MRI and MEG was helpful in the localization of epileptogenic zones for patients with IPICE, and MEG played a valuable role in this localization.

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