目的总结分段齿形结扎加皮桥整形术治疗环状混合痔的优、缺点。方法将我院2007年1月至2009年12月期间收治的80例环状混合痔患者按入院顺序简单随机分成2组,治疗组采用分段齿形结扎加皮桥整形术治疗,对照组采用传统的外剥内扎术,比较2组的疗效。结果治疗组治愈率为95%(38/40),对照组为90%(36/40),2组比较差异无统计学意义(Pgt;0.05); 治疗组较对照组的治愈时间明显缩短(Plt;0.05),术后疼痛、水肿、皮赘残留及肛管狭窄并发症方面更轻(Plt;0.05)。结论分段齿形结扎加皮桥整形术治疗环状混合痔比传统的外剥内扎术有更好的临床实用价值。
Objective To compare the difference of traumatic related index in serum and its significance between minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and open TLIF. Methods Sixty patients were enrolled by the entry criteria between May and November 2012, and were divided into MIS-TLIF group (n=30) and open TLIF group (n=30). There was no significant difference in gender, age, type of lesions, disease segment, and disease duration between 2 groups (P gt; 0.05). The operation time, intraoperative blood loss, and postoperative hospitalization time were recorded, and the pain severity of incision was evaluated by visual analog scale (VAS). The serum levels of C-reactive protein (CRP) and creatine kinase (CK) were measured at preoperation and at 24 hours postoperatively. The levels of interleukin 6 (IL-6), IL-10, and tumor necrosis factor α (TNF-α) in serum were measured at preoperation and at 2, 4, 8, and 24 hours after operation. Results The operation time, intraoperative blood loss, and postoperative hospitalization time of MIS-TLIF group were significantly smaller than those of open TLIF group (P lt; 0.05), and the VAS score for incision pain in MIS-TLIF group was significantly lower than that of open TLIF group at 1, 2, and 3 days after operation (P lt; 0.05). The levels of CRP, CK, IL-6, and IL-10 in MIS-TLIF group were significantly lower than those in open TLIF group at 24 hours after operation (P lt; 0.05), but there was no significant difference between 2 groups before operation (P gt; 0.05). No significant difference was found in TNF-α level between 2 groups at pre- and post-operation (P gt; 0.05). Conclusion Compared with the open-TLIF, MIS-TLIF may significantly reduce tissue injury and systemic inflammatory reactions during the early postoperative period.
目的探讨胸中上段食管癌淋巴结清扫的合理范围。 方法回顾性分析2010年1月至2013年10月我院134例胸中上段食管癌淋巴结清扫患者的临床资料。将患者分为两组:三野组,56例,男50例、女6例,年龄(55.4±9.6)岁,行三野淋巴结清扫根治术;二野组,78例,男69例、女9例,年龄(56.3±7.3)岁,行完全二野淋巴结清扫根治术。比较两组临床效果。 结果三野组患者淋巴结转移率明显高于二野组(60.7%vs.42.3%,P < 0.05),主要差别在于三野组有较高的颈部淋巴结转移率(21.4%)。三野组与二野组患者上纵隔淋巴结转移率分别为33.9%和30.8%,差异无统计学意义(P>0.05)。三野组及二野组患者术后并发症发生率差异无统计学意义(P>0.05)。三野组及二野组患者术后1年生存率分别为96.3%和85.5%,差异有统计学意义(P < 0.05);三野组及二野组患者术后1年内颈部淋巴结复发率分别为1.9%和11.8%,差异有统计学意义(P < 0.05)。 结论三野淋巴结清扫根治术有助于提高胸中上段食管癌手术根治性,能减少术后局部复发和转移,提高患者术后生存率,相对于完全二野淋巴结清扫术并不显著增加手术并发症。